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1.
Eur Rev Med Pharmacol Sci ; 28(3): 1089-1094, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38375714

ABSTRACT

OBJECTIVE: Recently, aesthetic rhinoplasty surgeries performed to change the external appearance have become increasingly common, especially among young people. This study examined the frequency of social appearance anxiety, self-esteem, and social media use in people with rhinoplasty surgeries for aesthetic concerns. SUBJECTS AND METHODS: A total of 76 people, including 27 healthy controls and 49 aesthetic rhinoplasty planned cases, were included in the study. All participants were administered the sociodemographic data form, Social Appearance Anxiety Scale (SAAS), Rosenberg Self-Esteem Scale (RSE), and Bergen Social Media Addiction Scale (BMSAS). RESULTS: The RSE score of the case group was significantly lower than the control group (p<0.001), and the SAAS (p=0.004) and BSMAS (p=0.005) scores were significantly higher. A significant negative correlation was observed between the RSE scale score, SAAS, and BMSAS. There was a significant positive relationship between SAAS and BSMAS. Cut-off values were determined using the ROC analysis. When the value of 1.41 was taken as the cut-off for RSE, 81.6% sensitivity and 74.1% specificity were found and were good predictors. When the value of 21 was taken as the cut-off for SAAS, 83.7% sensitivity and 51.9% specificity were found, and it was found to be a good predictor. When the value of 19 was taken as the cut-off for BSMAS, 42.9% sensitivity, and 88.9% specificity were found, and it was found to be a good predictor. CONCLUSIONS: People who undergo aesthetic rhinoplasty have high social appearance anxiety and self-esteem and frequent use of social media. More extensive sample studies are needed to examine the effects of this situation on rhinoplasty.


Subject(s)
Rhinoplasty , Social Media , Humans , Adolescent , Self Concept , Esthetics , Anxiety
2.
J Laryngol Otol ; 138(2): 184-187, 2024 Feb.
Article in English | MEDLINE | ID: mdl-37615109

ABSTRACT

OBJECTIVE: This study investigated the psychological status of patients with unilateral or bilateral complete nasal obstruction. METHOD: The study included 49 consecutive cases of unilateral or bilateral complete nasal obstruction. In order to assess participants' personality traits, both groups completed the Personality Belief Questionnaire, State-Trait Anxiety Inventory form, Beck Depression Inventory and Beck Anxiety Inventory. RESULTS: The groups were similar in terms of demographic characteristics. Patients with unilateral or bilateral complete nasal obstruction had higher scores on all the psychological assessments compared with the healthy controls, except for the Beck Anxiety Inventory. Although all personality assessment scores were higher in patients, the only differences that were statistically significant were in the dependent, antisocial and avoidant personality trait scores. CONCLUSION: The psychological conditions of patients with structural deformities that cause nasal obstruction may be affected, and appropriate treatment should be provided to improve their symptoms and quality of life.


Subject(s)
Nasal Obstruction , Adult , Humans , Nasal Obstruction/diagnosis , Quality of Life , Anxiety/etiology , Anxiety/psychology , Depression/etiology , Depression/psychology
3.
J Laryngol Otol ; 133(7): 600-603, 2019 Jul.
Article in English | MEDLINE | ID: mdl-31232258

ABSTRACT

OBJECTIVE: The aim of this study was to examine whether melatonin is involved in the pathogenesis of nasal polyposis. METHOD: This study included 29 patients with nasal polyposis and undergoing functional endoscopic sinus surgery. As a control group, 26 patients who had been operated on for a deviated nasal septum and concha bullosa were enrolled. Samples were taken from the nasal polyp tissue and from the resected middle concha bullosa mucosa of the control group. Serum samples were taken from all patients. RESULTS: It was found that the tissue and serum melatonin levels in the nasal polyp group were significantly lower compared with the tissue and serum melatonin levels in the control group. CONCLUSION: In nasal polyposis, the melatonin level in the serum and tissue is lower than in individuals without polyposis. This deficiency may play a role in the pathogenesis of nasal polyposis.


Subject(s)
Melatonin/deficiency , Nasal Polyps/etiology , Nose Deformities, Acquired/surgery , Paranasal Sinuses/surgery , Adult , Endoscopy , Female , Humans , Male , Melatonin/blood , Nasal Polyps/metabolism , Nasal Polyps/surgery , Nose Deformities, Acquired/metabolism , Paranasal Sinuses/metabolism
4.
J Laryngol Otol ; 126(1): 38-42, 2012 Jan.
Article in English | MEDLINE | ID: mdl-21888752

ABSTRACT

AIM: During nasal septum surgery, elevation of mucoperichondrium from the anterior nasal septum may be more difficult than from the medial and posterior septum. This study aimed to evaluate any histological structural differences between the anterior and posterior nasal septum cartilage, mucoperichondrium and intervening tissue. MATERIAL AND METHOD: Unilateral mucoperichondrial flap elevation without infiltration was performed, after nasal tip and dorsum decortication, in four patients undergoing open septorhinoplasty. Full-thickness samples, including cartilage and mucoperichondrium, were removed from the anterior and posterior nasal septum and examined under light and electron microscopy. RESULTS: Light microscopy showed no difference between anterior and posterior septum specimens regarding perichondrial thickness and subperichondrial cell density. Demarcation between cartilage and perichondrium and between perichondrium and lamina propria was more regular in the posterior versus the anterior septum. Electron microscopy showed no difference in chondroblast activity at the two sites. CONCLUSION: The observed tissue demarcation irregularities may explain the greater reported difficulty in elevating anterior versus posterior nasal septum mucoperichondrium. Immunohistochemical examination would further elucidate these interstructural connections.


Subject(s)
Connective Tissue/ultrastructure , Nasal Cartilages/ultrastructure , Nasal Mucosa/ultrastructure , Adult , Chondrocytes/physiology , Extracellular Matrix/metabolism , Female , Humans , Male , Nasal Cartilages/surgery , Nasal Mucosa/surgery , Nasal Septum/surgery , Rhinoplasty/methods , Surgical Flaps
5.
Rhinology ; 49(1): 112-6, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21468385

ABSTRACT

OBJECTIVES: The olfactory bulb (OB) is a remarkably plastic structure with highly active afferent neurons, which is partly reflected by its volume. Although deterioration of olfaction after total laryngectomy is reported by many patients, this problem has not received widespread attention. There has been no study that had addresses this loss olfactory ability as a function of OB volume. The aim of this study was to determine OB volume changes after laryngectomy. STUDY DESIGN: Twenty one patients post-total laryngectomy and 17 subjects with normal olfactory function underwent magnetic resonance imaging (MRI) for volumetric measurement of the OB. The history of all participants was taken in detail to exclude other possible causes of smell dysfunction. Volumetric measurement of the OB was performed by manual segmentation of the OB into coronal slices. Olfactory function was assessed with the orthonasal olfaction test. RESULTS: There was no statistically significant difference in volume between the right and left sides of the OB in the study and control groups. However, the study group had smaller OB volumes than the control group. In our assessment of orthonasal olfaction, patients who were post-total laryngectomy had worse orthonasal olfactory function than the control group. There were significant correlations between OB volumes and orthonasal test scores. CONCLUSIONS: Our MRI study showed that post-total laryngectomy patients had higher rates of olfactory bulb atrophy than the control subjects. Laryngectomy is associated with measurable decreases in olfactory function and this study hopes to further clarify this association by demonstrating that patients with total laryngectomy have reduced OB volumes when compared to the normal population.


Subject(s)
Olfaction Disorders/physiopathology , Olfactory Bulb/pathology , Adult , Aged , Cross-Sectional Studies , Female , Humans , Laryngectomy , Magnetic Resonance Imaging , Male , Middle Aged , Neuronal Plasticity , Olfactory Bulb/physiopathology , Smell/physiology
6.
J Laryngol Otol ; 125(2): 181-7, 2011 Feb.
Article in English | MEDLINE | ID: mdl-21059279

ABSTRACT

BACKGROUND: Patients with squamous cell carcinoma of the head and neck constitute a high risk group for synchronous and metachronous tumours. OBJECTIVE: This study aimed to investigate the usefulness of white light and autofluorescence bronchoscopy in the evaluation of pre-malignant and early neoplastic lesions in patients with laryngeal cancer, who are at high risk of concomitant lung cancer. METHODS: This prospective, cross-sectional study included 30 patients who had undergone total laryngectomy for squamous cell carcinoma of the larynx. The tracheobronchial system was investigated for the presence of pre-malignant and malignant lesions, using a combination of white light and autofluorescence bronchoscopy. Biopsies were obtained from areas with a pathological appearance, and histopathological studies were performed. RESULTS: All patients had a permanent tracheostomy. Light and autofluorescence bronchoscopy indicated that the tracheobronchial system was normal in 11 patients. A total of 27 biopsies was taken from the remaining 19 patients, and revealed invasive squamous cell carcinoma in one patient and pre-malignant changes in six. CONCLUSION: Bronchoscopy is a valuable and practical tool for screening patients at high risk of lung cancer, and requires minimal intervention especially in patients with a permanent tracheostomy. Of the various bronchoscopic techniques becoming available, autofluorescence bronchoscopy shows promise for the detection of pre-invasive malignant changes of the tracheobronchial system in patients previously operated upon for laryngeal cancer.


Subject(s)
Bronchoscopy/methods , Carcinoma, Squamous Cell/pathology , Early Detection of Cancer/methods , Lung Neoplasms/pathology , Neoplasms, Second Primary/pathology , Precancerous Conditions/pathology , Adult , Aged , Biopsy , Carcinoma in Situ/diagnosis , Carcinoma in Situ/pathology , Carcinoma, Squamous Cell/diagnosis , Carcinoma, Squamous Cell/surgery , Cross-Sectional Studies , Fluorescence , Humans , Laryngeal Neoplasms/surgery , Laryngectomy , Lung Neoplasms/diagnosis , Male , Middle Aged , Neoplasms, Second Primary/diagnosis , Precancerous Conditions/diagnosis , Prospective Studies , Smoking/adverse effects , Tracheostomy
7.
B-ENT ; 6(2): 105-9, 2010.
Article in English | MEDLINE | ID: mdl-20681362

ABSTRACT

OBJECTIVES: The aim of this study was to determine whether levels of advanced oxidation protein products (AOPP) can be used a marker of oxidative stress in the etiology of nasal polyposis. MATERIALS AND METHODS: Twenty-four patients diagnosed with nasal polyposis in Haseki Education and Research Hospital ENT Department between March and June 2008 were included in the study. The AOPP serum levels in NP patients and 24 healthy controls were measured with spectrophotometry and the results were compared statistically. RESULTS: AOPP levels were significantly higher in the study group compared with the control group. CONCLUSION: Our findings suggest that AOPP levels can be used as a marker of oxidative stress in patients with nasal polyposis. Future studies are neccessary to evaluate the efficacy of antioxidant therapy.


Subject(s)
Blood Proteins/analysis , Nasal Polyps/metabolism , Oxidative Stress/physiology , Adult , Biomarkers/blood , Female , Humans , Male , Middle Aged , Reactive Oxygen Species/metabolism
8.
J Laryngol Otol ; 124(7): 753-8, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20193100

ABSTRACT

OBJECTIVES: This study was designed to investigate the effects of the tissue adhesive N-butyl cyanoacrylate on nasal septal tissues after septal surgery in a rabbit model. METHODS: Forty-two adult New Zealand rabbits were randomly divided into three groups (14 in each group): septoplasty alone, septoplasty plus N-butyl cyanoacrylate, and controls. The open approach was used to explore the nasal septum. After raising mucoperichondrial and mucoperiosteal flaps on both sides of the septum, the septum was detached from the nasal floor in the septoplasty alone and septoplasty plus N-butyl cyanoacrylate groups. In the septoplasty plus N-butyl cyanoacrylate group, the mucoperichondrial and mucoperiosteal flaps were fixed to the septum and the septum was fixed lateral to the nasal spine using N-butyl cyanoacrylate; in the septoplasty alone group, the septum was packed with Merocel. In the control group, no further septal surgery was performed after flap elevation. Animals were observed for bleeding and haematoma formation over the first 24 hours. Seven animals in each group were used to evaluate early histopathological effects on the septal tissues, at four weeks post-operatively; the other seven in each group were used to evaluate late effects, at 12 weeks. RESULTS: Haematoma formation was observed in 10 animals in the septoplasty alone group, in four animals in the control group, and in only one animal in the septoplasty plus N-butyl cyanoacrylate group. The difference in haematoma incidence between the septoplasty alone and the septoplasty plus N-butyl cyanoacrylate groups was significant (p = 0.000). Histopathological evaluation revealed no significant difference between the groups as regards granulation tissue formation at week four versus week 12; however, there was a significant difference between the septoplasty plus N-butyl cyanoacrylate group and the control groups as regards inflammation at week 12 (p = 0.038). There was a significant difference between the septoplasty plus N-butyl cyanoacrylate group and the septoplasty alone group as regards the composition of the bone-cartilage junction zone at week four (p = 0.001). There was also a significant difference between the septoplasty plus N-butyl cyanoacrylate group and the control group as regards the cellular structure of new cartilage formation at week 12 (p = 0.004). CONCLUSIONS: In this rabbit septoplasty model, N-butyl cyanoacrylate appeared to be an effective nasal tissue adhesive, with a low complication rate.


Subject(s)
Enbucrilate/therapeutic use , Nasal Septum/surgery , Tissue Adhesives/therapeutic use , Wound Healing/drug effects , Animals , Case-Control Studies , Female , Male , Models, Animal , Nasal Septum/drug effects , Rabbits , Random Allocation , Rhinoplasty/methods
9.
J Laryngol Otol ; 124(2): 180-4, 2010 Feb.
Article in English | MEDLINE | ID: mdl-19943988

ABSTRACT

OBJECTIVES: To compare the efficacy and safety of radiofrequency and monopolar electrocautery tonsillectomy, regarding operation duration and tonsillectomy morbidity, including post-operative pain and haemorrhage and tonsillar fossa healing, in patients with recurrent chronic tonsillitis. STUDY DESIGN: A prospective, randomised, double-blind, controlled clinical study. METHODS: Fifty patients aged over 10 years who required tonsillectomy were randomly assigned to have one tonsil removed by radiofrequency and the other by monopolar electrocautery. Operation duration, post-operative haemorrhage, post-operative pain and tonsillar fossa wound healing were compared. RESULTS: The mean +/- standard deviation of the operation duration required for the radiofrequency method was significantly longer than that for monopolar electrocautery: 8.1 +/- 1.6 minutes vs 7.3 +/- 1.5 minutes, respectively (p = 0.034). Post-operative haemorrhage was observed in only three patients (13.6 per cent). Inter-group analysis showed no significant differences in post-operative pain scores for the radiofrequency vs monopolar electrocautery methods (3.7 +/- 1.6 vs 3.3 +/- 1.4, respectively; p < 0.126). Inter-group analysis showed that tonsillar fossa wound healing scores evaluated on the fifth, 10th and 14th post-operative days were significantly higher in the radiofrequency group compared with the monopolar electrocautery group (p < 0.001). CONCLUSION: The present study results indicated that monopolar electrocautery tonsillectomy was superior to radiofrequency tonsillectomy in terms of post-operative tonsillar fossa wound healing; however, both techniques were comparable in terms of post-operative pain.


Subject(s)
Catheter Ablation/methods , Electrocoagulation/methods , Tonsillectomy/methods , Tonsillitis/surgery , Adolescent , Adult , Double-Blind Method , Female , Humans , Male , Pain Measurement , Pain, Postoperative/diagnosis , Postoperative Complications/prevention & control , Postoperative Hemorrhage/prevention & control , Prospective Studies , Tonsillectomy/adverse effects , Wound Healing , Young Adult
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