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Z Naturforsch C J Biosci ; 64(1-2): 37-42, 2009.
Article in English | MEDLINE | ID: mdl-19323264

ABSTRACT

Two new mexicanolide-type limonoids, named xylomexicanin A (1) and xylomexicanin B (2), were isolated from seeds of the Chinese mangrove Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic methods. Compound 1 exhibited antiproliferative activity against human breast carcinoma cells (KT), while 2 did not show inhibitory effects on eleven human tumour cell lines tested.


Subject(s)
Antineoplastic Agents/chemistry , Antineoplastic Agents/pharmacology , Breast Neoplasms/drug therapy , Limonins/chemistry , Limonins/pharmacology , Meliaceae/chemistry , Neoplasms/drug therapy , Seeds/chemistry , Antineoplastic Agents/isolation & purification , Asia, Southeastern , Cell Line, Tumor/drug effects , Female , Humans , Limonins/isolation & purification , Magnetic Resonance Spectroscopy , Medicine, Traditional
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