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Intrathecal methotrexate-induced acute chorea.
Necioglu Orken, Dilek; Yldrmak, Yldz; Kenangil, Gülay; Kandraloglu, Nursu; Forta, Hulki; Celik, Münevver.
J Pediatr Hematol Oncol ; 31(1): 57-8, 2009 Jan.
Article in English | MEDLINE | ID: mdl-19125090

ABSTRACT

Intrathecal methotrexate is the mainstay of central nervous system prophylaxis in acute lymphoblastic leukemia. We describe a patient who developed acute chorea after last dose of intrathecal methotrexate therapy and recovered completely.


Subject(s)
Antimetabolites, Antineoplastic/adverse effects , Chorea/chemically induced , Methotrexate/adverse effects , Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy , Acute Disease , Antimetabolites, Antineoplastic/administration & dosage , Child , Chorea/drug therapy , Female , Humans , Injections, Spinal , Methotrexate/administration & dosage , Treatment Outcome
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