ABSTRACT
There were examined 64 patients, suffering combined gastroduodenal ulcers. Subpopulations of lymphocytes, using monoclonal antibodies, were used to estimate the patients immune status. The investigation was performed in a dynamics: immediately after admittance to hospital, on the operation day and on the tenth postoperative day. In 33 patients (the main group) reamberin was applied in a complex of surgical treatment and in 31 (the comparison group)--the conventional medicinal preparations. In all the patients before the treatment conduction there were revealed the cell immunity chain disorders like in a secondary immune deficiency state (SIDS). The SIDS elimination and the immunological indices improvement were promoted by incorporation of reamberin in the complex of surgical treatment.
Subject(s)
Immunologic Deficiency Syndromes/immunology , Peptic Ulcer/immunology , Peptic Ulcer/surgery , Adult , Female , Humans , Immunologic Deficiency Syndromes/complications , Lymphocyte Count , Lymphocyte Subsets/immunology , Male , Meglumine/analogs & derivatives , Meglumine/therapeutic use , Middle Aged , Succinates/therapeutic useABSTRACT
Operative intervention, aiming to decompress a biliary system in the patients, suffering choledocholithiasis, durable obturation jaundice, severe hepatic insufficience, gives often poor outcomes, high lethality and high complications ratio. Obturation jaundice and hepatic insufficiency, occurring on its background, coincide with accumulation of significant quantity of water soluble and protein connected toxins in the blood. A patient state improvement, the intoxication severity reduction, objectively confirmed by bilirubin level lowering in the blood, the transaminases and alkaline phosphatase activity lowering were noted under the influence of plasmapheresis application.
