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1.
Intern Med ; 58(1): 63-66, 2019 Jan 01.
Article in English | MEDLINE | ID: mdl-30146603

ABSTRACT

Anisakiasis involves the stomach in most cases and occurs rarely in the small intestine. Anisakiasis in the small intestine is associated with abdominal pain and obstruction and is rarely associated with intestinal bleeding. Unlike in the stomach, anisakiasis in the small intestine is difficult to diagnose anatomically. The patient in this case study developed hypovolemic shock due to excessive bleeding and underwent emergency surgery. With the recent increase in the consumption of raw fish around the world, this report provides an important finding of bleeding in the small intestine due to an unknown cause.


Subject(s)
Anisakiasis/diagnosis , Endoscopy , Intestine, Small , Abdominal Pain/etiology , Anisakiasis/pathology , Anisakiasis/surgery , Gastrointestinal Hemorrhage/etiology , Humans , Intestinal Obstruction/etiology , Male , Middle Aged , Raw Foods , Seafood
2.
Sci Rep ; 8(1): 402, 2018 01 10.
Article in English | MEDLINE | ID: mdl-29321655

ABSTRACT

Depression is implicated as a risk factor for the recurrence of inflammatory bowel disease (IBD). Near-infrared spectroscopy (NIRS) and brain-derived neurotrophic factor (BDNF) are useful tools for evaluation of brain activity and a depressive state, respectively. The aim of this study was to clarify the association between brain activity or depressive symptoms and IBD using NIRS and BDNF. This study included 36 ulcerative colitis (UC) patients, 32 Crohn's disease (CD) patients, and 17 healthy controls (HC). Center for Epidemiologic Studies Depression Scale (CES-D) scores were determined, NIRS was performed, and serum BDNF levels were measured in all subjects. NIRS showed that the mean oxygenated hemoglobin concentration was significantly lower in the frontal lobe in the UC group than in the HC group (HC 167 ± 106 vs. UC 83.1 ± 85.3, p < 0.05). No significant difference was seen between the HC and CD groups. There were also no significant differences in CED-D scores and BDNF levels among the groups. Changes in the NIRS values of the UC group may indicate decreased brain activity and a fundamental difference between UC and CD, which are often lumped together as two types of IBD.


Subject(s)
Brain/diagnostic imaging , Colitis, Ulcerative/psychology , Crohn Disease/psychology , Depression/diagnostic imaging , Spectroscopy, Near-Infrared/methods , Adolescent , Adult , Aged , Brain-Derived Neurotrophic Factor/blood , Case-Control Studies , Colitis, Ulcerative/blood , Colitis, Ulcerative/diagnostic imaging , Crohn Disease/blood , Crohn Disease/diagnostic imaging , Depression/blood , Female , Humans , Male , Middle Aged , Risk Factors , Young Adult
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