ABSTRACT
Objective To analyze the clinical infection distribution and drug resistance status of 442 strains of Escherichia coli to provide the basise for the treatment of Escherichia coli infection and the control of nosocomial infection.Methods The clinically submitted various kinds of specimens during 2013 were performed the bacterial culture and identification.The susceptibility of Escherichia coli to commonly used bacterial drugs were detected by adopting the MIC method.The data were analyzed by WHO-NET V5.5 and SPSS V13.0 softwares.Results 442 strains of Escherichia coli were isolated from the middle urine and secretion. The detection rate of ESBLs-producing Escherichia coli was 61.3%.442 strains of Escherichia coli had the high resistance to peni-cillins,cephalosporins and fluoroquinolones,better sensitivity toβ-lactam/β-lactamase inhibitor compounds and highest sensitivity to carbapenems.ESBLs-producing Escherichia coli had the higher resistance to commonly used antibacterial drugs than non-ESBLs-producing Escherichia coli .Conclusion The drug resistance of Escherichia coli is severe.ESBLs-producing Escherichia coli are u-sually resistant to many different types of antimicrobial drugs.Carbapenems are the first choice to treatment of severe infections of Escherichia coli .
ABSTRACT
OBJECTIVE To study the staphylococcus infection and the drug resistance among the outpetients and the inpatients, and to provide information for the clinical treatment.METHODS To cultivate and isolate bacteria according to the Clinical Laboratory Operation Regulation.Bacteria were identified with the automated analyzer VITEK-60.made by Bio-Merieux Company in France.The drug susceptibility was one with the method of single split agar diffusion.RESULTS Totally 159 strains of Staphylococcus were isolated from the outpatients,(46.1%) of which were MRSA.Most of the infection were caused through genital tract;390 strains of(Staphylococcus) were(isolated) from the inpatients,87.1% of which were MRSA.Most of the infection were caused through respiratory tract.Most of MSSA resisted to penicillin,but MRSA were sensitive to vancomycin and(teicoplanin.) (CONCLUSIONS) Preventing the spread of the MRSA is very important to the control of the nosocomial(infection).As far as the infective situation,most of the outpatients are infected through genital tract;while most of the inpatients are infected through respiratory tract.As far as the drug susceptibility,vancomycin is the best antibiotics,the next is teicoplanin.It is necessary to use combined drugs for the MRSA infection.
