ABSTRACT
In real image coding systems, block-based coding is often applied on images contaminated by camera sensor noises such as Poisson noises, which cause complicated types of noises called compressed Poisson noises. Although many restoration methods have recently been proposed for compressed images, they do not provide satisfactory performance on the challenging compressed Poisson noises. This is mainly due to (i) inaccurate modeling regarding the image degradation, (ii) the signal-dependent noise property, and (iii) the lack of analysis on intercorrelation distortion. In this paper, we focused on the challenging issues in practical image coding systems and propose a compressed Poisson noise reduction scheme based on a secondary domain intercorrelation enhanced network. Specifically, we introduced a compressed Poisson noise corruption model and combined the secondary domain intercorrelation prior with a deep neural network especially designed for signal-dependent compression noise reduction. Experimental results showed that the proposed network is superior to the existing state-of-the-art restoration alternatives on classical images, the LIVE1 dataset, and the SIDD dataset.
ABSTRACT
Camellia japonica is a popular garden plant in Asia and widely used as cosmetic sources and traditional medicine. However, the possibility that C. japonica affects cardiovascular system remains unclear. The aim of the present study was to evaluate vascular effects of an extract of C. japonica. Vascular reactivity was assessed in organ baths using porcine coronary arteries and inhibition of proliferation and migration were assessed using human vascular smooth muscle cells (VSMCs). All four different parts, leaf, stem, flower, and fruits, caused concentration-dependent relaxations and C. japonica fruit (CJF) extract showed the strongest vasorelaxation and its effect was endothelium dependent. Relaxations to CJF were markedly reduced by inhibitor of endothelial nitric oxide synthase (eNOS) and inhibitor of PI3-kinase, but not affected by inhibitor of cyclooxygenase and endothelium-derived hyperpolarizing factor-mediated response. CJF induced activated a time- and concentration-dependent phosphorylation of eNOS in endothelial cells. Altogether, these studies have demonstrated that CJF is a potent endothelium-dependent vasodilator and this effect was involved in, at least in part, PI3K-eNOS-NO pathway. Moreover, CJF attenuated TNF-α induced proliferation and PDGF-BB induced migration of VSMCs. The present findings indicate that CJF could be a valuable candidate of herbal medicine for cardiovascular diseases associated with endothelial dysfunction and atherosclerosis.
