1.
Angew Chem Int Ed Engl
; 50(9): 2125-8, 2011 Feb 25.
Article
in English
| MEDLINE
| ID: mdl-21344566
2.
Chem Biodivers
; 5(3): 359-74, 2008 Mar.
Article
in English
| MEDLINE
| ID: mdl-18357559
ABSTRACT
Selenium-containing amino acids have attracted increasing interest from view points of the importance as active centers of several selenoenzymes, the biological synthesis, the metabolism, and the use for structure determination of proteins. In this article, our recent progresses in the transformation from sulfur-containing amino acids to selenocysteine (SeCys) and selenomethionine (SeMet) derivatives are reviewed along with the surveys of general organic methodologies for the synthesis of SeCys and SeMet derivatives in the literature. The S-->Se modification (i.e., the chemical atomic mutation) would be a useful approach to peptide synthesis involving selenoamino acid residues.