ABSTRACT
An 80-year-old man presented with continuous spike fever and night sweats. Computed tomographic scans revealed a poorly demarcated mass in the upper part of the right kidney, which was resected. At surgery, tumorous lesions were not found in the abdominal cavity. Serum IgG4 level measured after surgery was 40.1mg/dl. Macroscopically, renal parenchyma of the upper part was replaced by an irregularly shaped grayish-white lesion of elastic, firm consistency. Histologically, the lesion consisted mostly of fibrous tissue in which small lymphoid cells, often with formation of aggregates, were evident. IgG4-positive plasma cells were few in number. Careful macroscopic examination revealed several minute nodules, which histologically consisted of large lymphoid cells, small lymphoid cells, and macrophages. These large lymphoid cells were positive for CD20 and contained Epstein-Barr virus (EBV) genome. Taken together, a diagnosis of EBV-positive B-cell lymphoproliferative disease (LPD) developing in inflammatory pseudotumor (IPT) of the kidney was made. This is the first report of B-LPD in IPT of the kidney. In addition, a presence of EBV in renal lymphoma cells has not yet been reported.
Subject(s)
B-Lymphocytes/pathology , Epstein-Barr Virus Infections/pathology , Granuloma, Plasma Cell/pathology , Kidney Diseases/pathology , Lymphoproliferative Disorders/pathology , Aged, 80 and over , Epstein-Barr Virus Infections/complications , Granuloma, Plasma Cell/complications , Humans , Hyperlipidemias/complications , Hypertension/complications , Kidney Diseases/complications , Kidney Diseases/virology , Lymphoproliferative Disorders/complications , Lymphoproliferative Disorders/virology , MaleABSTRACT
We retrospectively analyzed the records of 21 patients with penile carcinoma treated between January 1993 and February 2007. According to TMN classification (UICC 2002), 9, 8, 2 and 2 patients belonged to stages I, II, III and IV, respectively. During the follow up period of 4 to 144 months (median 15 months), the overall 5-year survival rate was 75.8%. All three patients having N2 died within one year. Lymph node metastasis (p = 0.001) and organ metastasis (p = 0.007) were found to be unfavorable prognostic factors for patients with penile cancer.
Subject(s)
Penile Neoplasms/mortality , Adult , Aged , Aged, 80 and over , Humans , Male , Middle Aged , Penile Neoplasms/therapy , Prognosis , Retrospective StudiesABSTRACT
The patient was a 36-year-old male with a chief complaint of painless mass in the perineum. An elastic and immobile mass with the tip of thumb finger size was palpable in the left perineum and magnetic resonance imaging (MRI) showed the tumor with high intensity on T2 weighted image from perineum through left scrotum. The tumor was surgically removed and a histopathological study revealed epidermoid cyst.
