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Chem Commun (Camb)
; 56(68): 9854-9857, 2020 Aug 25.
Article
in English
| MEDLINE
| ID: mdl-32840527
ABSTRACT
A novel and efficient NHC-catalyzed [3+3] annulation of enals with pyrrol-4-ones was developed, thus providing the dihydropyrano[3,2-b]pyrrol-5-one core structures with broad scope and good to excellent enantioselectivities. Notably, this strategy could also expand to the synthesis of axially chiral compounds and polysubstituted indoles.