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1.
Front Psychol ; 12: 731284, 2021.
Article in English | MEDLINE | ID: mdl-34925138

ABSTRACT

The economic restructuring and rapid rise of the economy in Northeast China have resulted in a proliferation of new ventures. Studying the psychology of new entrepreneurs is conducive to understanding the relationship between human capital and economic growth. The work reported here aims to explore the impact of human capital on economic growth in Northeast China and the influencing factors of psychological capital of new entrepreneurs in the entrepreneurial process. Based on Cobb-Douglas production function, the relationship between labor, physical capital, or human capital and economic growth in Northeast China is analyzed by econometric methods, and a model of human capital and economic growth in Northeast China is constructed. Besides, a psychological capital intervention (PCI) model is proposed to develop the psychological capital of new entrepreneurs, and the psychological quality structure model of entrepreneurial entrepreneurs and its operation mechanism. The results of the empirical analysis demonstrate that the elasticity coefficient of human capital in Northeast China is 0.15902, five times smaller than that of labor and physical capital. Moreover, 70% of new ventures are willing to accept higher education. The fitting degree of using the PCI model to develop the psychological capital of new ventures is only 0.3%. In addition, the modified external environment PCI instead of the external environment PCI model has a huge operating potential in the macro-entrepreneurial environment. In conclusion, the impact of human capital on economic growth in the northeast is smaller than the impact of labor and material capital investment on regional economic growth. The development of human capital and research on the composition and mechanism of psychological quality of entrepreneurial entrepreneurs are of significant theoretical and practical values to promote the economic growth in the northeast.

2.
Front Psychol ; 12: 690690, 2021.
Article in English | MEDLINE | ID: mdl-34456805

ABSTRACT

Against the background of economic globalization, the awareness of college student startup entrepreneurs toward mass entrepreneurship and innovation is analyzed from the perspective of educational psychology, thus responding to national development strategies. First, the status quo of innovation and entrepreneurship education is understood by literature analysis. Second, the existing innovation and entrepreneurship education in colleges and universities is investigated with a questionnaire survey (QS) and interviews to discover the challenges that college students face during innovation and entrepreneurship. The QS results provide a data basis for subsequent strategies. The results demonstrate that 19.86% of the students have a complete understanding of innovation and entrepreneurship, while only 9.93% of the students are interested in innovation and entrepreneurship activities. The technical significance of innovation and entrepreneurship activities only accounts for 41.84%. Moreover, the vast majority of students (79.67%) believe that the curriculum of innovation and entrepreneurship education is single, simple, and irrelevant to their majors. Meanwhile, some problems have been found: for example, the teaching faculty is insufficient, and there is not a sound entrepreneurial atmosphere. As per the survey results, an innovation and entrepreneurship education strategy for core stakeholders, namely, universities, society, government, university teachers, and students, is formulated to promote the sound development of innovation and entrepreneurship education in colleges and universities. Besides, a training strategy in line with the awareness of college students toward mass entrepreneurship and innovation is formulated based on the current situation of innovation and entrepreneurship education, which can serve as a reference and has practical significance for enriching and perfecting the innovation and entrepreneurship education system for college students.

3.
Front Pharmacol ; 12: 644129, 2021.
Article in English | MEDLINE | ID: mdl-34093184

ABSTRACT

Hepatic gluconeogenesis plays an important role in maintaining the body's glucose metabolism homeostasis. Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver diseases, when combined with type 2 diabetes mellitus (T2DM), it can cause severe glucose metabolism disorders. Studies have confirmed that chronic liver inflammatory lesions are the basis of T2DM combined with NAFLD (T2DM-NAFLD), inhibiting liver inflammation can improve glucose metabolism disorders. It is essential to explore safe and effective drugs to inhibit liver inflammation to improve the body's glucose metabolism disorders. Bicyclol is a biphenyl derivative that has anti-oxidative and anti-inflammatory properties. In the present study, the hepatoprotective effects and underlying mechanisms of bicyclol in T2DM-NAFLD were investigated, and T2DM-NAFLD with/without bicyclol treatment models were established. The results revealed that bicyclol alleviated fasting blood glucose, serum transaminase levels, insulin resistance, hepatic adipogenesis, lipid accumulation and markedly reduced T2DM-NAFLD rat histological alterations of livers. Not only that, bicyclol markedly attenuated T2DM-NAFLD induced production of inflammation factors (IL-1ß and TNF-α). Moreover, bicyclol suppressed the expression of insulin/gluconeogenesis signaling pathway (Akt, PGC-1α and PEPCK). These findings suggested that bicyclol might be a potentially effective drug for the treatment of T2DM-NAFLD and other metabolic disorders.

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