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1.
J Cancer Res Ther ; 18(5): 1360-1371, 2022 Sep.
Article in English | MEDLINE | ID: mdl-36204884

ABSTRACT

Objective: To determine the relationship between female body image and female sexual dysfunction (FSD) in young patients (20-40 years) with postoperative breast cancer. Methods: Using the convenient sampling method, we identified 276 young patients with postoperative breast cancer from June 2017 to 2019 in the Department of Oncology and Radiotherapy of the First Affiliated Hospital of Anhui Medical University to be included in the study. A general situation questionnaire for body image scale (BIS) and female sexual function index (FSFI) scale was used to evaluate the correlation between body image level and the prevalence of FSD in young patients with postoperative breast cancer. Results: The total score for BIS was 10.98 ± 7.19, indicating that patients were moderately dissatisfied with their body image The total prevalence of FSD was 63.41%. Pearson correlation analysis showed a negative correlation between the total score, each dimension score of BIS, total FSD, and the incidence of each dimension disorder (range, r: -0.414 to -0.717, all P values <0.05). Conclusion: There is a negative correlation between the body image level and the prevalence of FSD in young patients with postoperative breast cancer. This suggests that clinical medical workers should develop an intervention plan to improve the body image level of postoperative young breast cancer patients according to the unique physiological and psychological characteristics of these patients while also reducing the prevalence of FSD.


Subject(s)
Breast Neoplasms , Sexual Dysfunction, Physiological , Body Image , Breast Neoplasms/complications , Breast Neoplasms/surgery , Female , Humans , Prevalence , Sexual Dysfunction, Physiological/epidemiology , Sexual Dysfunction, Physiological/etiology , Surveys and Questionnaires
2.
Brain Imaging Behav ; 8(1): 97-101, 2014 Mar.
Article in English | MEDLINE | ID: mdl-23955491

ABSTRACT

This study investigates changes in substantia nigra metabolites in Parkinson's disease (PD) using proton magnetic resonance spectroscopy ((1)H- MRS). Thirty patients with asymmetric PD and 20 normal controls were included in this study. Substantia nigra metabolites were detected in all subjects using 3D-multimer (1)H-MRS with a 3.0 T MRI scanner. The relative ratios of NAA/Cr, NAA/Cho, NAA/(Cho + Cr) in the substantia nigra were compared between two sides of asymmetric PD patients as well as between PD patients and controls. Significant differences in NAA/Cr, NAA/Cho, NAA/(Cho + Cr) were observed between PD patients and healthy controls (P < 0.05) as well as between the ipsilateral and contralateral of affected extremity in PD patients (P < 0.05). Significant differences in NAA/Cr, NAA/Cho, NAA/(Cho + Cr) were also observed between patients with mild and severe PD. Thus, we found that (1)H-MRS can be used to detect substantia nigra metabolites in PD patients, which may be useful for early diagnosis and evaluation of PD.


Subject(s)
Parkinson Disease/metabolism , Substantia Nigra/metabolism , Adult , Aged , Choline/metabolism , Creatine/metabolism , Dipeptides/metabolism , Female , Humans , Magnetic Resonance Spectroscopy , Male , Middle Aged , Protons
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