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1.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi ; 31(4): 446-449, 2019 Jul 23.
Article in Chinese | MEDLINE | ID: mdl-31612687

ABSTRACT

Macrophage migration inhibitory factor (MIF), a type of pleiotropic immunoregulatory cytokine with a specific structure, participates in the regulation of host cell growth and migration and immune responses. Following parasitic infections, hosts may produce MIF and then participate in the parasite-host interactions. In addition, parasites may secrete parasite-derived MIF, and they jointly participate in parasite-host interactions. This paper reviews the regulation of MIF gene expression following parasitic infections, the role of MIF in parasite-host immune system interactions, and important signaling pathways of MIF-mediated immune responses.


Subject(s)
Host-Parasite Interactions/immunology , Macrophage Migration-Inhibitory Factors , Parasites , Animals , Gene Expression Regulation/immunology , Macrophage Migration-Inhibitory Factors/immunology , Parasites/immunology , Signal Transduction/immunology
2.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-818967

ABSTRACT

Macrophage migration inhibitory factor (MIF), a type of pleiotropic immunoregulatory cytokine with a specific structure, participates in the regulation of host cell growth and migration and immune responses. Following parasitic infections, hosts may produce MIF and then participate in the parasite-host interactions. In addition, parasites may secrete parasite-derived MIF, and they jointly participate in parasite-host interactions. This paper reviews the regulation of MIF gene expression following parasitic infections, the role of MIF in parasite-host immune system interactions, and important signaling pathways of MIF-mediated immune responses.

3.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-818515

ABSTRACT

Macrophage migration inhibitory factor (MIF), a type of pleiotropic immunoregulatory cytokine with a specific structure, participates in the regulation of host cell growth and migration and immune responses. Following parasitic infections, hosts may produce MIF and then participate in the parasite-host interactions. In addition, parasites may secrete parasite-derived MIF, and they jointly participate in parasite-host interactions. This paper reviews the regulation of MIF gene expression following parasitic infections, the role of MIF in parasite-host immune system interactions, and important signaling pathways of MIF-mediated immune responses.

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