Cross-sectional study of zero-medicine markup policy, prescribing trends and drug indicators using WHO/INRUD methodology in Chinese Jingzhou area.

In order to get the baseline data of Chinese Zero-Medicine Markup Policy, before any administrative intervention we investigated the drug indicators, the prescribing trends and economic data. In accordance with the WHO/INRUD criteria and cross-sectional studies, the retrospective methods along with equal sample interval of systematic sampling were used. We sampled from daily prescriptions and calculated the means over a twelve day period. We sampled from 38,246 adult prescriptions, the sampling percent was 3.06% and the drugs prescribed by generic name were 100.00%. During 2012-2014, the percentage of antibiotic cost in the total daily drug cost decreased from 17.44% to 8.01%, the percentage of prescriptions with antibiotic prescribed decreased from 12.64% to 9.64%, the percentage of encounters with an injection prescribed decreased from 15.21% to 12.77%. The average drug cost per antibiotic prescription ranged from ¥169.33 to 186.66. By comparing the related data, Zero-Medicine Markup Policy had greatly affected prescribing indicators, some indicators had a decreasing trend and became more rational, Zero-Markup Medicine Policy decreased both the patient-level and hospital-level drug expenses, and the reformation of the Zero-Medicine Markup Policy was steadily advanced.

Application and Rationality Evaluation of Hemostatic Drugs in the Patients with Subarachnoid Hemorrhage / 中国药师

Objective:To investigate the current use situation of hemostatics in preventing re-bleeding in the patients with sub-arachnoid hemorrhage. Methods:The records of patients with subarachnoid hemorrhage were selected from a hospital in 2016 and the types,dosage,course and drug adverse reactions of hemostatics were recorded and evaluated according to the drug information leaflets/related guideline,drug utilization researches and adverse drug actions monitoring. Results:Totally 81 cases with hemostatics involved 3 varieties of hemostatic drugs,the combination proportion was 16.05%,the reasonable use rate was 86.42%,the reasonable rate of administration route was 100%,the reasonable solvent rate was 98.77% and the course no more than 72 h was 88.89%. The drug uti-lization index of etamsylate injection and tranexamic acid injection was greater than one,indicating that the dosage was unreasonable. There were no adverse reactions in the 81 cases.Conclusion:The use of hemostatics in the patients with subarachnoid hemorrhage is common,and there is still unreasonable use (such as dosage and course etc) that we should pay attention to.