[Morphologial changes in the hair follicle and hair shaft in old age.]

The work is based on the results of a microscopic examination of 46 men and 50 women who were examined at the medical center for the treatment of hair and skin in the period 2022-2023. Depending on the age of the subjects, they were divided into two groups. The first group included 52 people (25 men and 27 women) of young age (21-35 years old). The second group consisted of 44 people (21 men and 23 women) of senile age (75-86 years old). Hair sampling was performed in the temporal region of the head by combing out the hair that had already fallen out with a comb (they did not pull it out of the skin!). The sample of this study consisted of conditionally healthy individuals of the Slavic phenotype. The width of the hair follicle and the hair shaft were calculated. The results of this lifetime comparative analysis of the linear dimensions of the hair follicle and the hair shaft in the temporal region in persons of both sexes of young and old age allow us to expand the understanding of the features of their age-related changes, and further continue detailed study, since new knowledge is necessary for the development of modern methods for the prevention of age-associated pathologies of the scalp.

Infections, Pandemics, and Sleep Disorders.

Studies of the neurological symptoms and signs associated with the acute and late phases of infectious diseases are important in pandemic conditions. The novel coronavirus infection (COVID-19) pandemic has increased the number of patients with sleeplessness, this being an adverse prognostic factor for infections. This review addresses the factors and mechanisms of sleep impairments and their relationship with inflammation and immune system dysfunction in infectious diseases. In particular, impairments to the functioning of the melatoninergic system are discussed as the cause of sleeplessness during pandemics. The relevance of developing measures for rehabilitating patients, particularly use of Sonnovan to restore normal sleep, which plays a fundamental role in supporting people's mental and physical health, is emphasized.

[Infections, pandemics and sleep disorders]. / Infektsii, pandemii i narusheniya sna.

The study of neurological symptoms and signs connected with acute and long-term periods of infectious diseases is relevant during pandemics. The COVID-19 pandemic has increased the number of patients suffering from insomnia. Sleep disturbance is an unfavorable prognostic factor for infections. Risk factors and mechanisms of sleep disturbance, their relationship with inflammation and dysfunction of the immune system in infectious diseases are presented. In particular, dysfunction of the melatonergic system as the cause of insomnia during pandemics is considered. The authors highlight the relevance of measures aimed at the rehabilitation of patients, in particular, the use of sonnovan to restore normal sleep, which is important for a person's mental and physical health.

[Dementia with Lewy bodies in a patient with oromandibular dystonia]. / Dementsiya s tel'tsami Levi u patsientki s oromandibulyarnoi distoniei.

Dementia with Lewy bodies (DLB) is characterized by a combination of progressive cognitive, motor impairments and autonomic dysfunction. Motor impairments in DLB may manifest themselves with mild parkinsonian signs as well as with classic parkinsonism. A case of a female patient, who developed LBD 5 years after being diagnosed with oromandibular dystonia, is presented.