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1.
Sci Rep ; 9(1): 13609, 2019 09 20.
Article in English | MEDLINE | ID: mdl-31541168

ABSTRACT

Assortative matching (AM) can be theoretically an effective means to facilitate cooperation. We designed a controlled lab experiment with three treatments on multi-round prisoner's dilemma. With matching based on weighted history (WH) as surrogate for AM, we show that adding pro-social dummies to the WH treatment may significantly improve cooperation, compared to both the random matching and the WH treatment. In society where assortative matching is effective and promoted by the underlying culture, institutional promotion of virtue role models can be interpreted as generating additional pro-social dummies, so as to move the initial state of cooperators into the basin of attraction for a highly cooperative polymorphic equilibrium.

2.
Spat Spatiotemporal Epidemiol ; 5: 39-50, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23725886

ABSTRACT

Spatial data often possess multiple components, such as local clusters and global clustering, and these effects are not easy to be separated. In this study, we propose an approach to deal with the cases where both global clustering and local clusters exist simultaneously. The proposed method is a two-stage approach, estimating the autocorrelation by an EM algorithm and detecting the clusters by a generalized least square method. It reduces the influence of global dependence on detecting local clusters and has lower false alarms. Simulations and the sudden infant disease syndrome data of North Carolina are used to illustrate the difference between the proposed method and the spatial scan statistic.


Subject(s)
Cluster Analysis , Sudden Infant Death/epidemiology , Algorithms , Computer Simulation , Humans , Infant , Least-Squares Analysis , Models, Statistical , Monte Carlo Method , North Carolina/epidemiology , Spatial Analysis
3.
Int J Health Geogr ; 12: 25, 2013 May 06.
Article in English | MEDLINE | ID: mdl-23648001

ABSTRACT

BACKGROUND: There are many applications for spatial cluster detection and more detection methods have been proposed in recent years. Most cluster detection methods are efficient in detecting circular (or circular-like) clusters, but the methods which can detect irregular-shaped clusters usually require a lot of computing time. METHODS: We propose a new spatial detection algorithm for lattice data. The proposed method can be separated into two stages: the first stage determines the significant cells with unusual occurrences (i.e., individual clustering) by applying the Choynowski's test, and the second stage determines if there are clusters based on the information of the first stage by a binomial approximate method. We first use computer simulation to evaluate the performance of the proposed method and compare it with the scan statistics. Furthermore, we take the Taiwan Cancer data in 2000 to illustrate the detection results of the scan statistics and the proposed method. RESULTS: The simulation results support using the proposed method when the population sizes are large and the study regions are irregular. However, in general, the scan statistics still have better power in detecting clusters, especially when the population sizes are not large. For the analysis of cancer data, the scan statistics tend to spot more clusters, and the clusters' shapes are close to circular (or elliptic). On the other hand, the proposed methods only find one cluster and cannot detect small-sized clusters. CONCLUSIONS: In brief, the proposed methods can detect both circular and non-circular clusters well when the significant cells are correctly detected by the Choynowski's method. In addition, the binomial-based method can handle the problem of multiple testing and save the computing time. On the other hand, both the circular and elliptical scan statistics have good power in detecting clusters, but tend to detect more clusters and have lower accuracy in detecting non-circular clusters.


Subject(s)
Computer Simulation , Disease Outbreaks/statistics & numerical data , Neoplasms/epidemiology , Spatial Analysis , Cluster Analysis , Female , Humans , Male , Neoplasms/diagnosis , Taiwan/epidemiology
4.
Am J Clin Nutr ; 83(6): 1289-96, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16762939

ABSTRACT

BACKGROUND: The beneficial effects of potassium-enriched salt on blood pressure have been reported in a few short-term trials. The long-term effects of potassium-enriched salt on cardiovascular mortality have not been carefully studied. OBJECTIVE: The objective was to examine the effects of potassium-enriched salt on cardiovascular disease (CVD) mortality and medical expenditures in elderly veterans. DESIGN: Five kitchens of a veteran retirement home were randomized into 2 groups (experimental or control) and veterans assigned to those kitchens were given either potassium-enriched salt (experimental group) or regular salt (control group) for approximately 31 mo. Information on death, health insurance claims, and dates that veterans moved in or out of the home was gathered. RESULTS: Altogether, 1981 veterans, 768 in the experimental [x (+/-SD) age: 74.8 +/- 7.1 y] and 1213 in the control (age: 74.9 +/- 6.7 y) groups, were included in the analysis. The experimental group had better CVD survivorship than did the control group. The incidence of CVD-related deaths was 13.1 per 1000 persons (27 deaths in 2057 person-years) and 20.5 per 1000 (66 deaths in 3218 person-years) for the experimental and control groups, respectively. A significant reduction in CVD mortality (age-adjusted hazard ratio: 0.59; 95% CI: 0.37, 0.95) was observed in the experimental group. Persons in the experimental group lived 0.3-0.90 y longer and spent significantly less (approximately US Dollars 426/y) in inpatient care for CVD than did the control group, after control for age and previous hospitalization expenditures. CONCLUSIONS: This study showed a long-term beneficial effect on CVD mortality and medical expenditure associated with a switch from regular salt to potassium-enriched salt in a group of elderly veterans. The effect was likely due to a major increase in potassium and a moderate reduction in sodium intakes.


Subject(s)
Cardiovascular Diseases/prevention & control , Health Care Costs/statistics & numerical data , Potassium Chloride/therapeutic use , Adult , Aged , Aged, 80 and over , Cardiovascular Diseases/classification , Cardiovascular Diseases/mortality , Humans , International Classification of Diseases , Male , Middle Aged , Potassium Chloride/administration & dosage , Proportional Hazards Models , Taiwan , Veterans
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