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1.
J Clin Transl Hepatol ; 10(3): 522-530, 2022 Jun 28.
Article in English | MEDLINE | ID: mdl-35836761

ABSTRACT

Recent reports of acute hepatitis of unknown origin in previously healthy children have been increasing worldwide. The main characteristics of the affected children were jaundice and gastrointestinal symptoms. Their serum aminotransaminase levels were above 500 IU/L, with negative tests for hepatitis viruses A-E. By 31 May 2022, the outbreak had affected over 800 children under the age of 16 years in more than 40 countries, resulting in acute liver failure in approximately 10%, including at least 21 deaths and 38 patients requiring liver transplantation. There was still no confirmed cause or causes, although there were several different working hypotheses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), adenovirus serotype 41, or SARS-CoV-2 superantigen-mediated immune cell activation. Here, we review early observations of the 2022 outbreak which may inform diagnosis, treatment, and prevention in the context of an overlapping COVID-19 pandemic.

2.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-305319

ABSTRACT

To offer the reference and method for salt damage in the cultivation of Marsdenia tenacissima, the seeds of M. tenacissima collected from Maguan city ( Yunnan province) were taken as the test materials to study the effects of different priming materials on improving germination and growth under high-level salt stress condition. Four different treatments, which were GA3, KNO3-KH2PO4, PEG-6000, NaCl, combined with ANOVA were applied to test the performance of germination energy, germination percentage, germination index, MDA, SOD, and CAT. The results showed that the seed germination was obviously inhibited under salt stress and the soaked seeds with different priming materials could alleviate the damage of salt stress. Under these treatments, the activities of SOD, CAT the content of soluble protein significantly increased. While the content of MDA significantly decreased. The maximum index was obtained when treated with 1.20% KNO3-KH2PO4, the germination percentage increased from 52.67% to 87.33% and the activity of SOD increased from 138.01 to 219.44 respectively. Comparing with the treatment of 1.20% KNO3-KH2PO4, the germination percentage of treating with 300 mg x L(-1) GA3 increased from 52.67% to 80.67%, while the activity of SOD increased from 138.01 to 444.61.


Subject(s)
Germination , Physiology , Marsdenia , Nitrates , Pharmacology , Polyethylene Glycols , Pharmacology , Potassium Compounds , Pharmacology , Seeds , Sodium Chloride , Pharmacology , Stress, Physiological , Xanthones , Pharmacology
3.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-315963

ABSTRACT

<p><b>OBJECTIVE</b>To study the ITS sequence variation of Pinellia ternata from different population in China, and it correlation to geographical distribution and morpha of the plant.</p><p><b>METHOD</b>The rDNA ITS regions of various P. ternata were amplified and sequenced. And they were analyzed by means of the software of CLUSTRAL and MEGA.</p><p><b>RESULT</b>Complete sequence of ITS and 5.8S rDNA of 16 different P. ternata population were obtained. The sequences of ITS1, 5.8S and ITS2 are 276,162 and 246 bp, respectively. ITS1 was more conservative than ITS2. Phylogenetic tree based on ITS1 and ITS2 sequences data was conducted by Neighbor-joining method.</p><p><b>CONCLUSION</b>Ribosomal DNA ITS sequence analyses can be applied to the resource research of P. ternata.</p>


Subject(s)
Base Sequence , China , DNA, Plant , Genetics , DNA, Ribosomal Spacer , Genetics , Ecosystem , Molecular Sequence Data , Phylogeny , Pinellia , Genetics , Plant Tubers , Genetics , Plants, Medicinal , Genetics , Genetics , Sequence Analysis, DNA
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