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1.
Rev. Assoc. Med. Bras. (1992) ; 67(10): 1432-1436, Oct. 2021. tab
Article in English | LILACS | ID: biblio-1351434

ABSTRACT

SUMMARY OBJECTIVE: Lung age estimation is a useful approach to determine pulmonary pathologies. In literature, no studies have evaluated and compared lung age in athletes with healthy volunteers. This study aims to compare lung age and respiratory muscle strength in female volleyball players and age-matched healthy volunteers. METHODS: A total of 18 female volleyball players (22.39±4.97 years) and 20 female healthy volunteers (24.85±3.33 years) were included. Pulmonary functions and respiratory muscle strength were assessed using a spirometer and mouth pressure device, respectively. The lung age was calculated using reference equations associated with gender, height, and forced expiratory volume in 1 second. RESULTS: Lung age was significantly lower, and forced expiratory volume in 1 L, forced vital capacity, and maximal inspiratory and expiratory pressure (cmH2O, %) were higher in female volleyball players compared with healthy volunteers (p≤0.05). CONCLUSION: The lung age and respiratory muscle strength of female volleyball players were better than healthy volunteers. Regular training in female volleyball players may improve respiratory functions and lung age.


Subject(s)
Humans , Female , Volleyball , Respiratory Muscles , Vital Capacity , Muscle Strength , Lung
2.
Rev Assoc Med Bras (1992) ; 67(10): 1432-1436, 2021 Oct.
Article in English | MEDLINE | ID: mdl-35018971

ABSTRACT

OBJECTIVE: Lung age estimation is a useful approach to determine pulmonary pathologies. In literature, no studies have evaluated and compared lung age in athletes with healthy volunteers. This study aims to compare lung age and respiratory muscle strength in female volleyball players and age-matched healthy volunteers. METHODS: A total of 18 female volleyball players (22.39±4.97 years) and 20 female healthy volunteers (24.85±3.33 years) were included. Pulmonary functions and respiratory muscle strength were assessed using a spirometer and mouth pressure device, respectively. The lung age was calculated using reference equations associated with gender, height, and forced expiratory volume in 1 second. RESULTS: Lung age was significantly lower, and forced expiratory volume in 1 L, forced vital capacity, and maximal inspiratory and expiratory pressure (cmH2O, %) were higher in female volleyball players compared with healthy volunteers (p≤0.05). CONCLUSION: The lung age and respiratory muscle strength of female volleyball players were better than healthy volunteers. Regular training in female volleyball players may improve respiratory functions and lung age.


Subject(s)
Volleyball , Female , Humans , Lung , Muscle Strength , Respiratory Muscles , Vital Capacity
3.
Geriatr Gerontol Int ; 19(5): 409-413, 2019 May.
Article in English | MEDLINE | ID: mdl-30884073

ABSTRACT

AIM: To determine the effect of two neuromuscular electrical stimulation (NMES) periods on quadriceps strength (QS) and functional performance in nursing home residents. METHODS: A total of 53 older adults living in a nursing home were randomized into two groups: NMES with a short stimulation period and NMES with a long stimulation period. The quadriceps muscles were bilaterally stimulated three times a week for 6 weeks in both groups. Strength was measured with a digital handheld dynamometer and 30-s chair stand test. Functional performance was evaluated with the Berg balance scale, Timed Up and Go test and 6-min walking test. RESULTS: Analysis was carried out on 44 older adults, who completed the study protocol. The isometric QS did not change within groups or between groups. Interestingly, the 30-s chair stand test score increased for both groups, but the improvements were similar among groups. The Berg balance scale score, Timed Up and Go test time and 6-min walking test distance also improved in both groups. However, no difference in any of the functional outcome measures was observed between groups. CONCLUSIONS: The present findings showed that both NMES protocols might be an alternative to achieve an improvement in functional strength of the lower extremities and functional performance in nursing home residents, whereas neither of the two protocols seems effective for improving isometric QS. Both methods might contribute to maintaining isometric QS during the aging process. Geriatr Gerontol Int 2019; 19: 409-413.


Subject(s)
Electric Stimulation Therapy/methods , Homes for the Aged , Lower Extremity/physiopathology , Nursing Homes , Physical Functional Performance , Quadriceps Muscle , Aged , Female , Humans , Male , Muscle Strength , Postural Balance , Treatment Outcome , Walk Test/methods
4.
Turk J Med Sci ; 47(3): 861-867, 2017 Jun 12.
Article in English | MEDLINE | ID: mdl-28618735

ABSTRACT

BACKGROUND/AIM: The pedicled transverse rectus abdominis myocutaneous (TRAM) flap remains widely used as a breast reconstruction technique. The bipedicled TRAM flap is not as preferable as it was formerly, mainly because of its donor site complications. However, in a number of situations, a bipedicled TRAM flap may be the only alternative. Therefore, a three-layer primary closure technique used with bipedicled TRAM flap breast reconstructions that can avoid donor site complications without using a mesh is presented. MATERIALS AND METHODS: A retrospective study was performed that included patients who underwent bipedicled TRAM flap breast reconstruction with the three-layer primary closure technique. Between 2000 and 2015, 124 breast reconstruction patients were reviewed for donor site morbidity. RESULTS: During the 15-year study period, 106 patients had conventional bipedicled TRAM flaps and 18 had bipedicled TRAM flaps with a surgical delay procedure. For all groups, none of the patients developed abdominal wall hernia, but three patients had bulging. Partial flap loss was the most common flap complication, present in 6 flaps (4.8%). CONCLUSION: The suturing technique studied provided abdominal wall closure without the use of a mesh even when utilizing a bilateral pedicle with very low complication rates.


Subject(s)
Abdominal Wound Closure Techniques , Mammaplasty , Surgical Flaps/surgery , Abdominal Wound Closure Techniques/adverse effects , Abdominal Wound Closure Techniques/statistics & numerical data , Adult , Female , Hernia, Abdominal , Humans , Mammaplasty/adverse effects , Mammaplasty/methods , Mammaplasty/statistics & numerical data , Middle Aged , Postoperative Complications , Retrospective Studies
5.
ANZ J Surg ; 85(1-2): 64-8, 2015 Jan.
Article in English | MEDLINE | ID: mdl-24754867

ABSTRACT

INTRODUCTION: Prophylactic mastectomy is performed to reduce the risk of breast cancer in high-risk conditions, and expectations about reconstruction are too high. Implant coverage with healthy tissue and skin reducing as an envelope are two concerns in the treatment of macromastia cases. We present our results obtained with a prosthetic reconstruction technique using an inferior pedicled de-epithelialized dermal flap after vertical-pattern skin-sparing mastectomy in this retrospective study. METHODS: Fourteen patients with macromastia and with a high risk of breast malignancy were treated with breast prosthesis using an inferior pedicled de-epithelialized dermal flap after vertical-pattern skin-sparing mastectomy, and were followed for 6 months to 2 years. RESULTS: Good aesthetic results were obtained in all of the patients with increased patient satisfaction. There were no serious complications and the patients were all satisfied. DISCUSSION: Since there is no dangerous T-point in vertical-pattern skin-sparing mastectomy in contrast to an inverted-T wise-pattern technique, where flaps are connected under great tension and susceptible to separation, it can be used safely in macromastia cases, as in smaller breasts. In addition, a de-epithelialized dermal flap is quite useful to cover the inferior pole of the prosthesis and it eliminates the need for an acellular dermal matrix.


Subject(s)
Breast/abnormalities , Hypertrophy/surgery , Mammaplasty , Mastectomy , Surgical Flaps , Adult , Breast/pathology , Breast/surgery , Female , Follow-Up Studies , Humans , Hypertrophy/pathology , Retrospective Studies , Treatment Outcome
6.
J Burn Care Res ; 34(4): e221-7, 2013.
Article in English | MEDLINE | ID: mdl-23702853

ABSTRACT

Postburn cervical contractures involving the anterior neck represent a serious social, public, and medical problem. The expanded supraclavicular artery flap is a good reconstructive option for these defects to improve functional and aesthetic appearance. Its main vascular supply is the supraclavicular artery, and it may be harvested as either a skin pedicled flap or an island flap. In our clinic, 10 patients with severe cervical burn contractures were reconstructed with preexpanded supraclavicular artery flaps between 2005 and 2012. All the flaps primarily healed with good functional and cosmetic results, and the donor sites primarily closed without any tension. A complete range of motion at the cervical region was obtained in all patients by the end of the reconstruction period. The preexpanded supraclavicular artery flap is a suitable alternative for coverage of the cervical defects after the release of the burn contractures. It is a thin tissue of both good color and texture, and is easy to harvest.


Subject(s)
Burns/complications , Contracture/surgery , Neck/surgery , Surgical Flaps , Burns/surgery , Contracture/etiology , Humans , Male , Surgical Flaps/blood supply , Tissue Expansion , Young Adult
8.
Plast Reconstr Surg ; 130(5): 651e-661e, 2012 Nov.
Article in English | MEDLINE | ID: mdl-23096619

ABSTRACT

BACKGROUND: One of the main causes of diabetic neuropathy is endoneurial edema, which increases the internal pressure of the perineurium, which has a tight structure. The treatment used to reduce internal pressure is perineurotomy, in which a surgical incision is made into the perineurium. METHODS: Forty male Sprague-Dawley rats were used in the study. They were classified into four groups. Streptozotocin-induced diabetes was created in groups III and IV. The sciatic nerve was transected and repaired epineurally in all groups. Perineurotomy was performed additionally in group II and IV to the sciatic, peroneal, tibial, and sural nerves from the most proximal side to their most distal ends. The sciatic function indices were calculated for functional assessment. Light and electron microscopic evaluations were performed for morphometric assessment. In addition, the myelinated and degenerated fibers were counted in all groups. RESULTS: The sciatic function indices of the diabetic perineurotomy group were found to be significantly higher than those of the other groups (p < 0.05). Based on the myelinated fiber counts, there was insignificant difference between group I and group II, whereas the difference was significant (p < 0.05) between group III and group IV. Presence of peripheric nerves in light microscopic evaluation revealed normal characteristics of myelinated fibers in group I and group II. The myelinated axon profile in group IV was similar to that of groups I and II in electron microscopic evaluation. CONCLUSION: It is concluded that perineurotomy may be established as a useful adjunctive procedure for nerve repair in diabetic patients.


Subject(s)
Diabetic Neuropathies/physiopathology , Diabetic Neuropathies/surgery , Nerve Regeneration , Perineum/surgery , Animals , Diabetes Mellitus, Experimental/physiopathology , Diabetes Mellitus, Experimental/surgery , Male , Peripheral Nerves/surgery , Rats , Rats, Sprague-Dawley , Sciatic Nerve/physiopathology
9.
Aesthetic Plast Surg ; 36(6): 1329-33, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23052383

ABSTRACT

BACKGROUND: Vertical techniques have become a growing area in reduction mammaplasty. Although it has many advantages such as a smaller scar and durable results, some problems still persist. The Hall-Findlay superomedial pedicle technique is one approach to obtain better results but is not without drawbacks. Some modifications are suggested to overcome its problems. METHODS: Superior pedicle vertical mammaplasty was performed for mastopexy, and superior, superomedial, and modified superomedial techniques were used for the reduction cases. Patients were followed up for at least 2 years and the complications were determined. RESULTS: Mastopexy cases had almost no complications. In reduction cases, the most common problems involved circulation and scar widening with the superior pedicle technique and bottoming-out deformity with the superomedial Hall-Findlay technique. These were negligible in its modified form. CONCLUSIONS: The tightness in the infra-areolar site is very important for a durable breast shape. Although the Hall-Findlay superomedial pedicle technique offers a versatile composite block nipple-areola complex with its sensation maintained, the inferior part of the pedicle that makes the medial pillar is in excess and the same amount of tissue must be removed from the lateral pillar to ensure tightness. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Subject(s)
Mammaplasty/adverse effects , Mammaplasty/methods , Female , Humans , Treatment Outcome
10.
J Reconstr Microsurg ; 28(4): 241-6, 2012 May.
Article in English | MEDLINE | ID: mdl-22411624

ABSTRACT

This is the first multicenter prospective study of outcomes of tibial neurolysis in diabetics with neuropathy and chronic compression of the tibial nerve in the tarsal tunnels. A total of 38 surgeons enrolled 628 patients using the same technique for diagnosis of compression, neurolysis of four medial ankle tunnels, and objective outcomes: ulceration, amputation, and hospitalization for foot infection. Contralateral limb tibial neurolysis occurred in 211 patients for a total of 839 operated limbs. Kaplan-Meier proportional hazards were used for analysis. New ulcerations occurred in 2 (0.2%) of 782 patients with no previous ulceration history, recurrent ulcerations in 2 (3.8%) of 57 patients with a previous ulcer history, and amputations in 1 (0.2%) of 839 at risk limbs. Admission to the hospital for foot infections was 0.6%. In patients with diabetic neuropathy and chronic tibial nerve compression, neurolysis can result in prevention of ulceration and amputation, and decrease in hospitalization for foot infection.


Subject(s)
Amputation, Surgical , Diabetic Foot/prevention & control , Diabetic Neuropathies/surgery , Foot/surgery , Hospitalization , Nerve Compression Syndromes/surgery , Tibial Nerve/surgery , Chronic Disease , Diabetic Foot/etiology , Humans , Infections/complications , Infections/therapy , Recurrence
11.
J Reconstr Microsurg ; 28(4): 235-40, 2012 May.
Article in English | MEDLINE | ID: mdl-22411625

ABSTRACT

Predictive ability of a positive Tinel sign over the tibial nerve in the tarsal was evaluated as a prognostic sign in determining sensory outcomes after distal tibial neurolysis in diabetics with chronic nerve compression at this location. Outcomes were evaluated with a visual analog score (VAS) for pain and measurements of the cutaneous pressure threshold/two-point discrimination. A multicenter prospective study enrolled 628 patients who had a positive Tinel sign. Of these patients, 465 (74%) had VAS >5. Each patient had a release of the tarsal tunnel and a neurolysis of the medial and lateral plantar and calcaneal tunnels. Subsequent, contralateral, identical surgery was done in 211 of the patients (152 of which had a VAS >5). Mean VAS score decreased from 8.5 to 2.0 (p <0.001) at 6 months, and remained at this level for 3.5 years. Sensibility improved from a loss of protective sensation to recovery of some two-point discrimination during this same time period. It is concluded that a positive Tinel sign over the tibial nerve at the tarsal tunnel in a diabetic patient with chronic nerve compression at this location predicts significant relief of pain and improvement in plantar sensibility.


Subject(s)
Decompression, Surgical , Diabetic Neuropathies/surgery , Nerve Compression Syndromes/surgery , Tibial Nerve/surgery , Ankle/innervation , Chronic Disease , Diagnostic Techniques, Neurological , Humans , Pain Measurement , Prognosis , Sensation , Tibial Nerve/physiopathology
12.
J Burn Care Res ; 32(3): 399-404, 2011.
Article in English | MEDLINE | ID: mdl-21422944

ABSTRACT

The frequency of assault by burning among all burn patients varies from country to country. Assault by burning, although uncommon, is a serious form of trauma and a significant source of morbidity and mortality. The aim of this retrospective study was to identify the epidemiologic features, current etiological factors, and the mortality of nine patients admitted to our burn unit between January 1999 and January 2009 after unexpected burn assault by paint thinner ignition caused by street children addicted to paint thinner. The circumstances of this injury and preventive measures are discussed.


Subject(s)
Behavior, Addictive/epidemiology , Burns/etiology , Burns/mortality , Homeless Youth/statistics & numerical data , Solvents/adverse effects , Adolescent , Adult , Age Factors , Burn Units/statistics & numerical data , Burns/therapy , Child , Cohort Studies , Fires , Humans , Incidence , Male , Paint/adverse effects , Retrospective Studies , Risk Assessment , Socioeconomic Factors , Solvents/chemistry , Survival Rate , Turkey/epidemiology , Urban Population , Young Adult
13.
J Craniofac Surg ; 21(4): 1024-8, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20613561

ABSTRACT

BACKGROUND: Facial burns are very common and have significant clinical impact. Facial scars are easily recognized in the community and become a source of lifelong guilt, shame, and regret for the patients. In the presented clinical study, we aimed to investigate the effectiveness of CO2 laser resurfacing and thin skin grafting for burn scars of face. METHODS: Sixteen white men, whose ages ranged from 20 to 26 years (mean, 22 y), were operated on for elimination of facial burn scars. Burn areas were de-epithelialized by CO2 laser. Each area was grafted with a split-thickness skin graft. The follow-up period for these patients ranged from 3 to 15 months, with a mean follow-up period of 9 months. RESULTS: The scars were successfully treated and converted to a socially acceptable appearance. The color match was good or excellent in all patients. No new hypertrophic scar developed. CONCLUSIONS: Facial burn scars may be dermabraded in a short time, and a bloodless and smooth raw surface may be created by a flashed-scanned CO2 laser. The CO2 laser resurfacing and thin skin grafting method is effective in treating facial burn scars.


Subject(s)
Burns/complications , Cicatrix/therapy , Facial Injuries/complications , Laser Therapy/methods , Skin Transplantation/methods , Adult , Carbon Dioxide , Cicatrix/etiology , Humans , Male , Treatment Outcome
14.
Burns ; 35(8): 1097-103, 2009 Dec.
Article in English | MEDLINE | ID: mdl-19766399

ABSTRACT

We compared the efficacy of silicone gel (Scarfade), silicone gel sheet (Epi-Derm), and topical onion extract including heparin and allantoin (Contractubex) for the treatment of hypertrophic scars. Forty-five postburn scars were included in the study. Patients with scars less than 6 months from injury were assigned at random to three groups each containing 15 scars, and their treatment was continued for 6 months. Scars were treated with Scarfade, Epiderm and Contractubex. Scar assessment was performed at the beginning of the treatment, and at the end of the sixth month when the treatment was completed by using the Vancouver scar scale. The difference between before and after treatment scores for each three groups was statistically significant. The difference between Scarfade group and Epi-Derm group was not significant; however, the differences of the other groups (Scarfade-Contractubex, Epiderm-Contractubex) were significant. Silicone products, either in gel or sheet, are superior to Contractubex in the treatment of the hypertrophic scar. The therapist should select the most appropriate agent according to the patient's need and guidelines of these signs.


Subject(s)
Allantoin/therapeutic use , Burns/complications , Cicatrix, Hypertrophic/therapy , Heparin/therapeutic use , Plant Extracts/therapeutic use , Silicone Gels/therapeutic use , Administration, Cutaneous , Adolescent , Adult , Child , Child, Preschool , Cicatrix, Hypertrophic/etiology , Cicatrix, Hypertrophic/pathology , Drug Combinations , Female , Humans , Male , Middle Aged , Severity of Illness Index , Skin Pigmentation/drug effects , Treatment Outcome , Young Adult
15.
Turk Neurosurg ; 19(1): 51-7, 2009 Jan.
Article in English | MEDLINE | ID: mdl-19263354

ABSTRACT

The carpal tunnel syndrome is the most common nerve entrapment syndrome. Many different methods have been described for treatment. We performed a novel method to release the carpal tunnel. Subsequently, we compared the surgery results of this novel limited incision technique and the standard longitudinal incision technique by using a 'Numerical Grading System'. There is no reported study about the use of 'Numerical Grading System' for assessment of carpal tunnel syndrome in the literature. The novel technique is simple and effective, employs inexpensive instruments, and has a low complication rate. The aim of this paper is to record a novel limited incision technique and a new assessment method for the carpal tunnel syndrome.


Subject(s)
Carpal Tunnel Syndrome/diagnosis , Carpal Tunnel Syndrome/surgery , Decompression, Surgical/methods , Preoperative Care/instrumentation , Severity of Illness Index , Adult , Aged , Carpal Tunnel Syndrome/physiopathology , Decompression, Surgical/instrumentation , Diagnosis, Computer-Assisted/instrumentation , Female , Follow-Up Studies , Hand Strength , Humans , Male , Middle Aged , Postoperative Complications/prevention & control , Pressure , Surgical Instruments , Transducers , Young Adult
16.
Forensic Sci Int ; 179(2-3): 144-6, 2008 Aug 06.
Article in English | MEDLINE | ID: mdl-18555629

ABSTRACT

Shooting range injuries are generally caused by ballistic accidents, and so far no burn disaster has been reported. In this article we reported a disaster caused by a gunpowder explosion in an indoor shooting range area in Istanbul, Turkey. Fourteen injured people were evacuated from the scene. Our burn center accepted 7 of them. Of the 7 injured people, 2 who were accepted by our burn center, and 3 people who were admitted by another center died. It is clearly identified how this mechanism of injury differs from that of usual burn injuries, due to both the high temperature generated, and the combination of hot and toxic gases produced by the explosion. We described the features of burn injury, and possible reasons of burn disasters.


Subject(s)
Burns/etiology , Disasters , Explosions , Firearms , Adult , Bandages , Burn Units , Burns/pathology , Burns/therapy , Confined Spaces , Female , Forensic Medicine , Humans , Intubation, Intratracheal , Length of Stay , Male , Middle Aged , Multiple Organ Failure/etiology , Respiration, Artificial , Sepsis/etiology , Trauma Severity Indices , Turkey
17.
J Reconstr Microsurg ; 24(2): 95-101, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18473283

ABSTRACT

We researched the effect of nerve decompression procedures on diabetic neuropathy cases just in the following day after surgery as well as later, at 6 months. Twenty-four patients with diabetic neuropathy who underwent surgical decompression were entered into this study. The common peroneal, the posterior tibial, and the deep peroneal nerves were decompressed. Visual analog scale was used for management of the pain. Patients were screened with neurosensory testing by using a Pressure-Specified Sensory Device. Preoperative values as well as values on the postoperative first day and 6 months postoperatively were compared. We found pain relief rate to be 80% at postoperative first day and 85% at 6 months postoperatively. Mean two-point discrimination length improvement rates were found to be 72.6% at postoperative first day and 89% at 6 months postoperatively, which mean excellent and good improvement. We concluded that peripheral nerve decompression can be used effectively in the treatment of diabetic neuropathy patients.


Subject(s)
Decompression, Surgical , Diabetic Neuropathies/surgery , Adult , Diabetic Neuropathies/physiopathology , Female , Humans , Male , Middle Aged , Pain Measurement , Time Factors , Treatment Outcome
19.
Plast Reconstr Surg ; 120(1): 68-77, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17572546

ABSTRACT

BACKGROUND: The technique of intraoperative vessel hydrostatic dilation is sometimes used to facilitate microvascular anastomosis and prevent vasospasm. Currently, delay procedures remain a reliable method of maximizing flap survival. The authors aimed to increase rat transverse rectus abdominis musculocutaneous (TRAM) flap viability by imitating the physical effect of a surgical delay procedure with hydrostatic dilation. METHODS: Forty-five male Sprague-Dawley rats were randomly assigned to one of three TRAM flap groups (15 rats in each group): the control group, the delay group, and the hydrostatic dilation group. The surgical delay procedure was performed by division of right-sided cranial epigastric vessels and contralateral superficial inferior epigastric vessels. While elevating the flap, hydrostatic dilation was performed to the cranial epigastric artery and vein with a mean pressure of 250 mm Hg. The groups were compared by means of microangiography and survival ratio of TRAM flaps and mean artery lumen area, mean vein lumen area, and mean artery wall area of the flap pedicle 48 hours after elevation. RESULTS: There was a significant difference between the control and hydrostatic dilation groups in favor of surface area viability and angiographic assessment (p < 0.01). Surgical delay has traditionally been accepted as the most reliable method of enhancing flap viability. No significant difference was revealed between the surgical delay and hydrostatic dilation groups (p > 0.05). In the hydrostatic dilation group, compared with the control group, an increase in vein diameter, a thinning of the artery wall, and an increase in lumen diameter were observed. CONCLUSIONS: The physical effect of blood flow is achieved acutely with hydrostatic dilation. This simple, dependable, one-stage hydrostatic dilation procedure can be used in clinical applications.


Subject(s)
Plastic Surgery Procedures/methods , Rectus Abdominis/blood supply , Surgical Flaps/blood supply , Angiography , Animals , Dilatation/methods , Disease Models, Animal , Epigastric Arteries/diagnostic imaging , Graft Rejection , Graft Survival , Male , Postoperative Complications , Probability , Random Allocation , Rats , Rats, Sprague-Dawley , Plastic Surgery Procedures/adverse effects , Rectus Abdominis/diagnostic imaging , Rectus Abdominis/transplantation , Reference Values , Risk Factors , Sensitivity and Specificity , Tissue and Organ Harvesting/methods
20.
Plast Reconstr Surg ; 116(6): 1697-705, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16267434

ABSTRACT

BACKGROUND: Considering a healthy nerve trunk as the hypothetically ideal conduit, a new experimental model using an intact nerve for bridging a nerve defect was contemplated. METHODS: Thirty rats were used. In group I (double coaptation), a segment was removed from the peroneal nerve. Both the proximal and distal stumps were repaired end-to-side to the tibial nerve. In group II (only distal coaptation), only the distal nerve stump was repaired. In group III (control), the transected segment was immediately repaired primarily in its original orientation as a nerve graft. A walking track analysis was conducted periodically for 28 months. The horseradish peroxidase retrograde labeling technique was used for tracking the origin of the axons presented in the distal stump of the peroneal nerve in group I, and morphologic studies were also carried out for all the groups. RESULTS: Functional assessment revealed that the difference between group I and group II was significant. The horseradish peroxidase labeling test suggested that the nerve fibers in the distal stump of the peroneal nerve were mostly from its original proximal stump passed by the way of the tibial nerve bridge. CONCLUSION: This study suggested that the axons of the proximal stump of a sectioned nerve can sprout into another intact nerve trunk by the way of an end-to-side repair site, regenerate, and advance in its epineurium distally for a distance and pass into its original distal stump if it was repaired end-to-side. It was thought that the technique could be used in clinical cases with short nerve defects as an alternative method to grafts and conduits.


Subject(s)
Axons/physiology , Nerve Regeneration/physiology , Peripheral Nerves/physiology , Anastomosis, Surgical , Animals , Horseradish Peroxidase , Models, Animal , Rats , Rats, Sprague-Dawley , Suture Techniques
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