ABSTRACT
OBJECTIVE@#To observe the effect of the three stages of 5-aminolevulinic acid-photodynamic therapy (ALA-PDT) on condyloma acuminatum of external urethral meatus.@*METHODS@#A total of 56 patients with condyloma acuminatum of external urethral meatus presenting at the Department of Dermatology of Xiangya Hospital from Janunary 2009 to September 2009 were randomly treated by the three stages of ALA-PDT. The topical ALA followed by PDT was carried out once a week for 3 weeks. Rates of cure, ineffectiveness, adverse effects and complications were observed. The follow-up time was 6 months and the recurrence rates were documented.@*RESULTS@#After treatment of three stages of ALA-PDT, complete remission was achieved in 48 out of the 56 patients (85.7%). The recurrence rate was 14.3% (8 cases), and 2 patients had no responses (3.6%). Only 1 patient had serious pain during the treatment, and the rate of adverse effect was 1.8%. No complications were observed.@*CONCLUSION@#The three stages of ALA-PDT are safe, effective and tolerant treatment for condyloma acuminatum of external urethral meatus.
Subject(s)
Adult , Humans , Male , Aminolevulinic Acid , Condylomata Acuminata , Drug Therapy , Photochemotherapy , Photosensitizing Agents , Urethral Diseases , Drug TherapyABSTRACT
BACKGROUND: Due to the trouble of body image and self-esteem, more and more women hope to reduce their body mass.OBJECTIVE: To assay the characters and correlation between body image and self-esteem in women who reduce weight positively.DESIGN: Transect investigation.SETTING: Department of Dermatology of Xiangya Hospital and Xiangya Second Hospital of Central South University. PARTICIPANTS: Totally 100 patients for weight loss was collected in Department of Acupuncture and Moxibustion of Xiangya Hospital Affiliated to Central South University from November 2002 to September 2003 and they were included in experimental group. Severe physical disorders or other chronic physical disorders were excluded, such as cardiac vascular disease and diabetes and various metal disturbances were excluded too. In addition,the patients did not taken psychoactive drugs recently. Those were in over-body-mass group if body mass index(BMI) ≥ 24 and those were in normal body mass group if BMI＜24. In the control, there were 100 healthy women participating in the study in volunteer at the same time. The exclusive standards for them were same as the experimental group and they did not taken psychoactive drugs recently and had done nothing for weight loss in 5 years.METHODS: After instructed, the receptors filled up the following questionnaire: a self-rating scale of body image(SRSBI) and the self-esteem scale (SES). SRSBI is the subjective assessment on the beauty and strength of the body individually. SES is the assessment on holistic perception of self-value and self-acceptance.MAIN OUTCOME MEASURES: Results of SRSBI and SES in weight loss women.RESULTS: According to intention, general results of SRSBI: The score in experimental group(15.14±9.99) was higher than that in the control (7.89±6.18) (t= 6.15, P＜0.001) . The score was(15.65±10.36) in normal body mass group and was(13.81 ±10.03) in over-body-mass group. By the comparison between both, no difference presented(t=0.91, P ＞0.05) . Results of SES: the score in experimental group (27.01±4.19)was lower than that in the control(28.23±3.65) (t= 2.16, P＜0.05).The score was(27.31±4.50) in normal body mass group and was (26.86±3.82) in over-body-mass group. By the comparison between both,no difference presented (t=0.54, P＞0.05) . It was indicated in linear correlation analysis on SRSBI and SES in experimental group that the correlation coefficient between SRSBI and SES was-0. 088(P＞0.05).CONCLUSION: The people who seek for weight loss actively present inferior subjective perception of body image and low level of self-esteem, and there is no correlation between both of them and neither of them is relevant t.o obesity.
