1.
Bull Exp Biol Med
; 153(4): 459-62, 2012 Aug.
Article
in English, Russian
| MEDLINE
| ID: mdl-22977844
ABSTRACT
Atherosclerotic plaque formation and vascular calcinosis were modeled in a subchronic experiment. Reduced HDL and elevated LDL concentrations, increased atherogenic index and albumin toxicity index, and high blood levels of triglycerides and uric acid were early markers of pathology. Xydiphone in combination with vitamin D effectively reduced these changes and the degree of vascular calcinosis.
Subject(s)
Atherosclerosis/drug therapy , Biomarkers/metabolism , Etidronic Acid/therapeutic use , Vascular Calcification/drug therapy , Alkaline Phosphatase/blood , Animals , Atherosclerosis/pathology , Cholesterol, LDL/blood , Creatine Kinase/blood , Creatinine/blood , Etidronic Acid/pharmacology , L-Lactate Dehydrogenase/blood , Lipid Peroxidation/physiology , Male , Rats , Serum Albumin , Triglycerides/blood , Uric Acid/blood , Vascular Calcification/pathology , Vitamin D/pharmacology , Vitamin D/therapeutic use
2.
Vopr Okhr Materin Det
; 14(4): 7-12, 1969 Apr.
Article
in Russian
| MEDLINE
| ID: mdl-5345278
