ABSTRACT
UNLABELLED: In modern world the risk of circulatory system diseases is increasing. Effective techniques are sought of prevention and detection of coronary artery disease. The development of diagnostic modalites is directed to reduction of invasiveness and risk for patients with providing as much information from a single examination, as possible. Gated scintigraphy examinations by single photon emission method (GSPET) seem to meet these requirements. They combine information that could be obtained as yet only with two separated examinations. They provide data on left ventricular perfusion and function. AIM OF THE STUDY: The aim of the study was application of gated single photon emission tomography (GSPET) technique by means of polar maps and beating cross-sections in the assessment of parameters describing left ventricular function in various degrees of myocardial perfusion disturbances. A comparison was also done of GSPET processing by polar map and beating cross-section methods in the diagnosis of perfusion disturbances. MATERIAL AND METHODS: The study group included 142 patients (mean age 55.8 +/- 10.9 years), in whom myocardial scintigraphic examination was carried out by GSPET method using Tc99m-MIBI complex according to two-day protocol. The examinations were performed using a two-head Varicam gamma camera. For study data processing Xpert Pro software for workstation was used. The examinations were analysed using both polar maps and beating cross-sections. Additional values were considered offered by gated GSPET examinations. In all, 284 examinations were analysed. The patients were divided into groups according to gender and changes in perfusion both in the maps and cross-sections. RESULTS: The total number of 112 consistent results of perfusion changes were obtained both in the polar maps and cross-sections (71%). Most differences were observed in the group with effort perfusion disturbances. During processing of GSPET examination by the method of polar maps were obtained more reversible perfusion disturbances then in the beating cross-sections, differences were found which required further studies and comparison with clinical data. CONCLUSIONS: On the basis of the obtained results the conclusions were drawn that processing of gated single photon emission tomography (GSPET) by methods of both polar maps and mobile cross-sections makes possible to assess the parameters describing left ventricular function at rest and during exercise in various degrees of myocardial perfusion disturbances.
Subject(s)
Coronary Disease/diagnosis , Coronary Disease/prevention & control , Gated Blood-Pool Imaging/methods , Myocardium/pathology , Tomography, Emission-Computed, Single-Photon/methods , Ventricular Dysfunction, Left/diagnosis , Body Surface Potential Mapping , Coronary Circulation , Coronary Disease/etiology , Female , Humans , Male , Middle Aged , Ventricular Dysfunction, Left/complicationsABSTRACT
The muscle bridge is an anomaly which is found in 0.5-2.5% of coronary angiography examinations and may lead to impairment of coronary blood flow. The clinical course of the disease may be heterogeneous--from completely asymptomatic to the development of myocardial infarction or severe ventricular arrhythmia. We present three patients with muscle bridge in the left anterior descending artery. The clinical course of the disease was different in each patient--from mild symptoms to cardiac arrest during exercise test.
Subject(s)
Coronary Stenosis/etiology , Coronary Stenosis/surgery , Coronary Vessel Anomalies/complications , Coronary Vessel Anomalies/surgery , Adrenergic beta-Antagonists/therapeutic use , Adult , Cineangiography , Coronary Angiography , Coronary Stenosis/drug therapy , Coronary Vessel Anomalies/diagnostic imaging , Coronary Vessel Anomalies/drug therapy , Electrocardiography , Humans , Male , Middle AgedABSTRACT
Primary Percutaneous Transluminal Coronary Angioplasty (PTCA) is increasingly common method of treatment patients with acute myocardial infarction. The aim of the study was to assess the left ventricular function in patients with myocardial infarction subjected to thrombolysis or primary PTCA. Gated Single Photon Emission Computed Tomography was performed in 40 patients 6 months after myocardial infarction treated either with thrombolysis or primary PTCA. Left ventricular ejection fraction (LVEF), left ventricular enddiastolic (LVED) and systolic (LVES) volumes were analysed both at rest and after stress. Six months after myocardial infarction LVEF was significantly greater and LVED, LVES volumes smaller in patients treated with primary PTCA in comparison to patients treated with thrombolysis. The above observation suggests that patients subjected to primary PTCA might have better functional outcome in comparison to matched patients treated with thrombolysis after 6 months post myocardial infarction.
