ABSTRACT
OBJECTIVE: We report a case of a multinodular goitre developing in a lingual thyroid. METHOD: Case report, and discussion of the embryology and treatment of lingual thyroids. CASE REPORT: A 66-year-old woman presented with dysphagia secondary to a multinodular lingual goitre. A previously silent lingual thyroid had undergone multinodular change to cause dysphagia and eventually airway compromise. The goitre was excised via a midline, mandible-splitting approach. CONCLUSION: Lingual thyroids have an incidence of one in 3,000 to 10,000. There has not previously been a reported case of such an ectopic gland undergoing multinodular changes and presenting in later life.
Subject(s)
Goiter, Nodular/complications , Lingual Thyroid/complications , Aged , Airway Obstruction/etiology , Deglutition Disorders/etiology , Female , Goiter, Nodular/diagnosis , Humans , Lingual Thyroid/diagnosis , Thyroid Gland/embryology , Thyroidectomy/methodsABSTRACT
We report a case of life-threatening nasal sinus zygomycosis that developed during remission induction therapy for a relapsed acute lymphoblastic leukaemia. The patient was successfully treated with liposomal amphotericin B and granulocyte-colony stimulating factor followed by surgical reconstruction of the resultant cutaneous defect.