ABSTRACT
Investigations carried out demonstrated acute pneumonia in young children to be characterized by the presence in the sputum from the deep respiratory tract of polymicrobial flora, in some of viral-microbial-fungus flora, and also of pneumocysts. Immunobiological and virological study demonstrated the etiological role of 7 virus species and 2 bacteria species in 70.8% of cases; pneumonia of viral etiology constituted 24.1 +/- 3.0%, of bacterial -- 24.6 +/- 3.0%, and of viral-bacterial -- 22.1 +/- 2.0%. In order to unify the approaches and methods of study of pneumonia etiology in young children complex immunomicrobiological, virological, and parasitological method of study is suggested.
Subject(s)
Pneumonia/etiology , Acute Disease , Child, Preschool , Humans , Infant , Pneumonia/immunology , Pneumonia/microbiology , Pneumonia/parasitology , Pneumonia, Viral/etiology , Sputum/immunology , Sputum/microbiologyABSTRACT
Bacteriological analysis of sputum of 598 children with acute pneumonia was performed. Sensivity of 1348 cultures belonging to 8 bacterial species with respect to benzylpenicillin, streptomycin, chloramphenicol, tetracycline, oxytetracycline, chlortetracycline, erythromycin, oleandomycin, neomycin and monomycin was determined. It was shown that the sputum microflora was often resistant to the antibiotics widely used in the medical practice for prolonged periods of time, such as benzylpenicillin, streptomycin, chloramphenicol, tetracyclines. However, it usually remained sunsitive to neomycin, monomycin, erythromycin and oleandomycin. It was found that antibioticogrammes defining the antibiotic choice were of great significance for therapy of acute pneumonia.