ABSTRACT
Two outbreaks of photosensitivity and jaundice in sheep grazing the grass, Brachiaria decumbens. In West Java in 1983 and 1983 and 1990 are described. Aggregates of acicular clefts and crystals were present in bile canaliculi, bile ducts, Kupffer cells, hepatocytes and in kidney tubules. The number of crystals increased with the length of exposure to the plant and sheep that died had the largest accumulations. These crystalline structures have been reported before in this syndrome, but are similar to those seen in Tribulus terrestris and Panicum spp toxicities.
Subject(s)
Disease Outbreaks/veterinary , Liver/pathology , Photosensitivity Disorders/veterinary , Plant Poisoning/veterinary , Sheep Diseases/etiology , Animals , Female , Indonesia , Kidney/pathology , Male , Photosensitivity Disorders/etiology , Photosensitivity Disorders/pathology , Plant Poisoning/complications , Plant Poisoning/pathology , Poaceae , Sheep , Sheep Diseases/pathology , Skin/pathologyABSTRACT
Basidiobolus haptosporus Drechsler causes human and animal disease in the tropics. This paper reports the isolation of this organism from natural substrates and describes the pathogenicity of the isolates. Basidiobolus was recovered from faecal samples of amphibians, reptiles and macropods, from woodlice, and from granulomatous skin lesions of horses. Some isolates were heat-tolerant. Almost all of the heat-tolerant isolates were pathogenic to suckling mice and had smooth or undulate, or smooth plus undulate zygospore walls. When inoculated intracerebrally into suckling mice they caused encephalomalacia, necrosis, meningoencephalitis, congestion, haemorrhage and a granulomatous reaction in the central nervous tissue, hydrocephalus and nervous signs. There was a variety of animal sources of pathogenic strains of the organism which were widely distributed in the sampling area, thus the potential hazard of infection could be more serious than previously considered.
Subject(s)
Fungi/isolation & purification , Mycoses/microbiology , Animals , Animals, Suckling , Brain/pathology , Fungi/growth & development , Fungi/pathogenicity , Hot Temperature , Mice , Mycoses/pathologyABSTRACT
Basidiobolus species lose their sporulation ability after relatively short periods of time in culture. This problem has been partially overcome by the use of media which incorporate glucosamine hydrochloride and casein hydrolysate. The media also appear to be suitable for the culture of Conidiobolus species.
