[Effect of dipyridamole on recombination of photooxidized bacteriochlorophylla and photoreduced primary quinone in reactive centers of purple bacteria and degradation of form M412 of bacteriorhodopsin]. / Bliiane dipiridamola na rekombinatsiiu fotookislennogo bakteriokhlorofilla i fotovosstanovlennogo pervichnogo khinona v reaktsionnykh tsentrakh purpurnykh bakterii i raspad formy M412 bakteriorodopsina.

It is shown that the addition of dipyridamole (2,6-bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4d]py rim idine) (up to 10(-4) M) leads to a drastic acceleration of the dark recombination reaction between photooxidized bacteriochlorophyll and photoreduced primary quinone in reaction centers of Rhodobacter sphaeroides. The value of the acceleration is similar to that registered under cryogenic temperatures. The extent of the effect of dipyridamole derivatives depended on their structure. In wild-type bacteriorhodopsin and D96N mutant, dipyridamole slowed down the Schiff base reprotonation (the kinetics of M412 form decay was registered). It is suggested that dipyridamole can influence the structural and dynamic state of membrane proteins by affecting the system of their hydrogen-bonds and thus modify electron and proton transport processes.

[The treatment of newborns with gastroschisis]. / Lechenie novorozhdennykh s gastroshizisom.

Gastroschisis is considered by the authors to be an embryopathy. The main principles of management of newborns with gastroschisis are: warming of the newborn, rehydration, measures against pseudoobstruction of the intestine. An effective method which could be recommended for all kinds of operations for defects of the anterior abdominal wall is a "manual enlargement of the abdominal cavity" during operation.

[Microsurgical methods in pediatric surgery]. / Mikrokhirurgicheskii metod v detskoi khirurgii.

The paper deals with the results of treatment of 32 children aged from 2 to 12 years with injuries to the arteries (n = 7), tendons of the hand and fingers (n = 9), nerves of the fingers (n = 3), cryptorchidism (n = 6), tumour of a finger (n = 1), and traumatic amputation of a finger (n = 1). Drainage of a lymph vessel in the foot for lymph infusion in +suppurative conditions was carried out in 8 patients. Optic magnification, inert suture material, and microsurgical instruments were used in the operations. The anatomical and functional results were excellent and good in 30 patients. In an 8-year-old girl, the results of a restorative operation on the flexor tendons of the ring finger of the left hand were satisfactory. In a boy two and a half years of age, replantation of the index finger of the left hand proved a failure. Microsurgical methods make it possible to attain utmost precision in forming vascular anastomoses, applying sutures to the nerves of the fingers and tendons, and in other operations. Microsurgery holds much promise in pediatric surgery.

[Gastroschisis]. / Gastroshizis.

The results of management of 7 newborns with gastroschisis in 1980-1987 are discussed. Four of them were treated by the earlier described method of "manual distention" of the abdominal cavity by stretching the abdominal wall with the finger, 3 patients recovered. The method was not applied to the other 3 patients and all of them died. It is emphasized that the baby must be kept warm in the preoperative period and hypovolemia must be controlled. In view of the prolonged paralytic ileus complete parenteral feeding must be prescribed in the postoperative period until the function of the gastrointestinal tract becomes normal. All the modern principles of management of these patients must be scrupulously followed in order to accomplish successful treatment and improve the results.