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1.
Article in Russian | MEDLINE | ID: mdl-9304339

ABSTRACT

In multiple experiments on golden hamsters, highly sensitive to glanders, the method of the transfer of antibacterial resistance was worked out. The most positive effect was obtained after the subcutaneous injection of saline-suspended marrow cells, obtained from white rats, infected with Burkholderia mallei C5 in a single inoculation and passaged through noninfected white rats 5 times. Out of 60 golden hamsters, treated with such material and subsequently (on day 21) injected with 1.0 x 10(2) B. mallei cells, 42 animals survived (70%).


Subject(s)
Glanders/immunology , Immunization, Passive/methods , Animals , Burkholderia/pathogenicity , Cricetinae , Disease Susceptibility , Female , Glanders/microbiology , Glanders/pathology , Immunity, Innate , Immunization, Passive/statistics & numerical data , Male , Mesocricetus , Pseudomonas/pathogenicity , Rats , Species Specificity , Transplantation Immunology/immunology , Virulence
2.
Article in Russian | MEDLINE | ID: mdl-9245146

ABSTRACT

The pathomorphology and cell-mediated response of the body to Burkholderia mallei in laboratory animals, highly sensitive and resistant to these bacteria. In the comparative study of the pathomorphology and pathogenesis of glanders in golden hamsters and white rats quantitative and qualitative differences in the histogenesis of response reaction and the morphology of immunocompetent organs were established. Cell-mediated reactions play a greater role in the limitation of the early spread of B. mallei in the host body than antigen-mediated mechanisms.


Subject(s)
Glanders/etiology , Glanders/pathology , Animals , Burkholderia/isolation & purification , Burkholderia/pathogenicity , Cricetinae , Female , Glanders/immunology , Glanders/microbiology , Immunity, Innate , L Forms/isolation & purification , L Forms/pathogenicity , Male , Mesocricetus , Rats , Time Factors , Virulence
3.
Aviakosm Ekolog Med ; 31(6): 51-5, 1997.
Article in Russian | MEDLINE | ID: mdl-9483282

ABSTRACT

The analysis of the study associated with cultivating the leaf cabbage, small radish in the Russian-Bulgarian greenhouse "Svet" aboard Mir orbital space station in 1990 has demonstrated that under microgravity conditions the zeolite substrate "Balkanin" with particles dimensions of 1-3 mm placed in the root modules of the greenhouse "Svet" did not ensure the sufficient transfer of the water from moisture-saturated wicks to the periphery of the vegetation vessels what is attributable to the peculiarities of hydrophysical characteristics of the substrate used. There presented the results of experimental research on the hydrophysical and agrochemical characteristics of the ion-exchange substrates of two other types--"Biona 312" and "Biona V" prepared on the basis of the artificial ion-exchange resins: cationite--CU-2 and anionite EDE-10P. For these substrates there found the estimates of humidity correlating with the loss of gassy pores as well as there measured the specific weight of the solid phase and the volumetric weight. There presented data on the content of the nutrients as well as the results of assessing the biological productivity potential of the tested substrates in the "Svet" greenhouse root modules. The characteristics obtained are indicative of the possibility to use the mentioned substrates in space greenhouse of the "Svet" type.


Subject(s)
Agrochemicals , Plant Development , Soil , Space Flight , Weightlessness , Time Factors , Zeolites
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