[Chemotherapy of Pseudomonas aeruginosa infections in children during the first three months of life]. / Khimioterapiia detei pervykh trekh mesiatsev zhizni s sinegnoinoi infektsiei.

The data on the efficacy of antibacterial drugs and their combinations in treatment of 150 three-month old infants with generalized infection due to Pseudomonas aeruginosa are presented. The clinical isolates of P. aeruginosa were found to be carriers of multiple drug resistance which markedly complicated the chemotherapy. Only combined antibacterial therapy of such infants proved to be rational. High activity of aminoglycosides, azlocillin and cefotaxime against P. aeruginosa and the synergistic action of their combinations observed in the patients permitted to recommend the use of combinations of the above drugs in the empirical chemotherapy.

[Antibiotic sensitivity of gram-negative opportunistic bacteria isolated from the feces of newborn infants with intestinal infections]. / Chuvstvitel'nost' k antibiotikam gramotritsatel'nykh aérobnykh uslovno-patogennykh bakterii, izolirovannykh iz isprazhnenii novorozhdennykh detei s kishechnymi infektsiiami.

Antibiotic sensitivity of 136 pure cultures of gram negative aerobic potentially pathogenic bacteria was assayed. The bacteria were isolated from feces of newborns with intestinal infections. It was shown that the majority of the strains were resistant to 4-5 antibiotics widely used in treatment of patients. However, they were sensitive to gentamicin and polymyxin M.