[Nanobiophotonics: photon-associated nanobiotechnology for laser and personalized medicine].

Analyzed are the literature in the field of development and use nanobiophotonic technologies for laser and personalized medicine. Arguably, the origins of nanobiophotonic are closely tied in the first experimental realization of near-field optics, which enabled optical imaging beyond the diffraction limit. The information about the gist of nanobiophotonics and other photon-associations technologies (photonics, nanophotonics, biophotonics, nanooptics, plasmonics, nanospectroscopy, laser and personalized medicine) is summarized. Nanobiophotonics is the use of light to image, probe and manipulate biological materials. The particular strength of nanobiophotonics is thet in ideal case it retains of the light for permits live cell sensing. The area of nanobiophotonics technologies is too broad to possible capture all aspects nano-analitic directions and biomedical research within the last years.

[Ischemic heart disease: from traditional surgery and standard therapy to cellular cardiomyoplasty and laser revascularization].

Myocardial ischemia and cardiac dysfunction have been known to follow ischemic heart disease cell therapy and laser revascularization harbors a promising potential for vascular and cardiac reparation, which is corroborated by adequate preclinical evidence. In this review we present an analysis research of mesenchymal stem cells transplantation and transmyocardial laser revascularization for myocardial repair.

[The mobile medical clinic: a role of mobile physician crews in the provision of health care for rural populations].

Medical mobile clinics (MMK) have several advantages: autonomous functioning, rapid reacting, mobility and universality, availability and also possibility of providing of medicare even in the most difficult of access and remote districts. For 2 the movable medical brigade of MMK is do more than 30 departures in 25 districts of six areas of Ukraine (Chernovithky, Nicolajevsky, Zhitomirsky and other regions), more than 6000 ultrasonic studies are undertaken, is carried out on nosologies with providing of consultative help narrow specialists. High efficiency of echography is confirmed as the first instrumental method of research at the inspection of wide layers of villagers resident in remote settlements. For a population development of pharm services appeared a comfortable help in the points of work of departure brigade of medicare, and also programs of humanitarian help.

[Molecular-cellular mechanisms of light radiation and weak magnetic fields on the blood status and microcirculation system (at therapeutic doses) with using modern magnetolaser equipment (review of the literature)].

This review covers the molecular-cellular mechanisms of therapeutic action of light and magnetic field on blood components, blood vessels and the microcirculation system. Noted the role of the magnetic field as a trigger of vasodilation/vasoconstriction, depending on the initial vascular tone. Discussed the importance of NO-dependent effects of magnetic field on the microcirculatory response and angiogenesis.

[Development on composite restoratives in therapeutic dentistry in first fifty years: photopolimerizable nanocomposites].

The authors have conducted an analysis of current scientific literature concerning studies of the development of dental nanocomposites and stage investigations into materials restoratives in first fifty years.

[Business activity in medicine: economic analysis of medical support programs and characteristics of management in business risks in health care system (problems and perspectives)].

Current scientific data on the assessment of cost expenditure on the realization of programs to assist medically patients with cardiological, oncological, rheumatologic and other diseases were analyzed. Peculiarities of the management of business risks were considered in the article. It was concluded that the management of business risks in health care system should be improved.

[Molecular medicine: current state, problems and perspectives of dental regeneration using stem cell in stomatology].

Possible impact of molecular technology (stem cells therapy) on origin and the development of dentoalveolar process of regeneration is considered in the survey article. The article presents molecular mechanisms of the dental organogenesis and features the beginning of regenerative growth of tooth's tissues with stem cells.

[Molecular medicine: proteomic diagnostic technology and methods of molecular therapy in arrhythmology].

This paper reviews the modern proteomic technologies used in arrhythmology. The authors discuss the methods of the proteomic analysis as a supplement to the analysis of gene structure and gene expression. Modern molecular-genetic technologies (cell therapy, gene therapy) enable to optimize treatment by controlling the origin and development of cardiac arrhythmias. It will be reached with the use of biological pacemaker cells in clinics.

[Apoptosis of cardiomyocytes, cytokines and remodeling of myocardium against the development of chronic heart failure].

A literature review considers apoptosis-related immunological aspects of chronic heart failure (CHF). Scientific data on the induction of cardiomiocyte apoptosis, NO and immune factors--cytokines in the development of CHF and remodeling of myocardium were analyzed. Modern approaches of therapy for patients with CHF were discussed in the article. They include combined correction of functioning mechanisms of neurohumoral systems and elimination of adverse effects of apoptosis--associated cytokine "aggression".

[Mental health and cardiovascular diseases: stress-induced arrhythmias, comorbidity of depression disorders].

The authors have conducted an analysis of current scientific literature concerning stress-induced arrhythmias. The article deals also with the question of relation between mental health and cardiovascular diseases, depressive disorders and arrhythmias, psychosocial stress and associated disorders of cardiovascular system as well as practical aspects of this relationship are discussed by the authors.

[Medical care cost: methodological aspects (foreign experience)]. / Stoimost' meditsinskoi pomoshchi: metodologicheskie aspekty (zarubezhnyi opyt).

The authors present and discuss a survey of published papers on medical care price formation. Economic analysis methods, socio-economic aspects of evaluation of medical care cost and effectiveness of different kinds of treatment were considered. Planning the volume of medical care in health care institutions strongly recommends perfecting the price formation by optimising calculation method and developing treatment and prophylaxis protocols.

[Medico-social legislation of Ukraine: organizational-legal aspects of management in the sphere of community health care (current state, problems and perspectives)]. / Mediko-sotsial'noe zakonodatel'stvo Ukrainy: organizatsionno-pravovye aspekty upravleniia v sfere okhrany zdorov'ia naseleniia (sostoianie, problemy i perspektivy).

The authors analyzed organizational-legal aspects of management in the sphere of community health care. The foundation of medical-legal base of public health is substantiated in the article. It enables to form new mechanisms aimed at improvement of medical care, creation of data-analytical system, unification of health care and diagnostics standards.

[Apoptosis in myocardial ischemia and reperfusion]. / Apoptoz pri ishemii i reperfuzii miokarda.

Apoptosis initiated in cells of tissues maintaining homeostasis under the influence of growth factors and hormones has been recently described during the early stage of myocardial infarction in the reperfusion zone of the cardiac muscle. Although it has been proved that apoptosis of cardiomyocytes plays one of the key roles in progression of the reperfusion syndrome, molecular and cellular mechanisms of this phenomenon are not yet resolved. Prospects are discussed of a new trend in preventive treatment of ischemic and reperfusion-related affection of the myocardium relying upon blocking of apoptosis of cardiomyocytes.

[The optimization of the anti-arrhythmia effect of kordaron and novocainamide by laser biostimulation therapy in a combined program for treating refractory tachyarrhythmias]. / Optimizatsiia protivoaritmicheskogo éffekta kordarona i novokainamida lazernoi biostimuliatsionnoi terapiei v kompleksnoi programme lecheniia refrakternykh takhiaritmii.

Antiarrhythmic action of He-Ne laser in combination with novocainamid and cordaron has been tried in the framework of the program on combined treatment of tachyarrhythmia. He-Ne laser irradiation has been found to optimize in refractory patients the effect of novocainamid which arrests the paroxysms and of cordarone which prevents paroxysms of atrial tachycardia, fibrillation, flutter.

[The psychological preparation of patients with a paroxysmal systolic tachyarrhythmia for helium-neon laser treatment]. / Psikhologicheskaia podgotovka bol'nykh s paroksizmal'noi takhisistolicheskoi aritmiei k lecheniiu gelievo-neonovym lazerom.

The psychological structure was studied in 120 patients with paroxysmal disorders of the cardiac rhythm. Anxiety, obsessive-phobic, neurasthenic and ergopathic syndromes were singled out. It was established that psychological aspects of personality of the patients depended on the course of paroxysmal disorders of the rhythm and influence the number of arrhythmia triggering that often reduced the grade of medicosocial adaptation. Psychological preparation of these patients to laser treatment may be achieved by rational psychotherapy. Details of such psychotherapy are discussed.

[The effect of peripheral cholinergic blockers on the cocarcinogenic action of an experimental influenza infection]. / Vliianie perifericheskikh kholinoblokatorov na kokantserogennoe deistvie éksperimental'noi grippoznoi infektsii.

The cocarcinogenic effect of chronic influenza infection was shown to be mediated by M-cholinergic structures. Administration of a M-anticholinergic agent in low dose at the key stages of chronic influenza infection development was followed by a nearly complete suppression of its cocarcinogenic action. N-anticholinergic agents failed to exert such effect.