ABSTRACT
While the lung cancer is detected, the majority of the patients could not be surgical cured. Thus appears the great necessity of prevention, of a more efficient treatment and the developing of new methods for early detection. The first screening trials for lung cancer had negative results. None of the studies had no prove in decreasing of mortality by screening for lung cancer. The lack of sensitivity of thoracic radiographs and sputum cytology was leading the investigators to use the monoclonal antibodies in detecting the neoplastic changes in sputum, the spiral computerized tomography with low dose of radiations, the autofluorescence bronchoscopy and more recent the positron emission tomography, offering the possibility of reducing mortality by early detection in lung cancer.
Subject(s)
Lung Neoplasms/diagnosis , Mass Screening/methods , Antibodies, Monoclonal , Bronchoscopy/methods , Diagnosis, Differential , Early Diagnosis , Fluorescent Antibody Technique , Humans , Lung Neoplasms/diagnostic imaging , Lung Neoplasms/pathology , Positron-Emission Tomography , Sensitivity and Specificity , Sputum/cytology , Tomography, Spiral ComputedABSTRACT
The Wegener's granulomatosis is characterized by the involvement of the upper airways, the lower airways and the late involvement of the kidneys. The authors are presenting in this article, the case of a 44 years old man, which presented the three conditions mentioned above, with an early kidney involvement and who died due to a major complication of the disease: the intravascular disiminated coagulation and a multivisceral vascular involvement, despite the correct and early treatment.
Subject(s)
Disseminated Intravascular Coagulation/etiology , Granulomatosis with Polyangiitis/complications , Adult , Cyclophosphamide/therapeutic use , Disseminated Intravascular Coagulation/diagnosis , Disseminated Intravascular Coagulation/drug therapy , Drug Therapy, Combination , Fatal Outcome , Granulomatosis with Polyangiitis/diagnosis , Granulomatosis with Polyangiitis/drug therapy , Humans , Male , Methylprednisolone/therapeutic useABSTRACT
Primary pleuro-pulmonary non-Hodgkin lymphomas are very rare tumors, possibly under diagnosed, with a very long, frequently asymptomatic evolution. The authors present the diagnostic difficulties of such pathology, in a particular case, which was diagnosed only by open biopsy and immunohistochemical analysis of tissue fragments. Chemotherapy and radiotherapy determined a favorable course of the disease.
Subject(s)
Lung Neoplasms/pathology , Lymphoma, Non-Hodgkin/pathology , Pleural Neoplasms/pathology , Adult , Biopsy , Diagnosis, Differential , Humans , Lung Neoplasms/therapy , Lymphoma, Non-Hodgkin/therapy , Male , Neoadjuvant Therapy , Pleural Neoplasms/therapy , Treatment OutcomeABSTRACT
The aim of this study was to appreciate the accuracy of the technique for sensitivity test for M. tuberculosis. We have tested the same bacterial strains (101) using the same drugs concentrations, by absolute concentration method, and we have compared the results obtained in two different laboratories. The concordance of the obtained results (94.05% for SM, 97.03% for INH, 99.01% for RMP, 100% for EMB) is in the limits of reproducibility obtained by other authors. The obtained results show a good technique for sensitivity test in the two laboratories.
