ABSTRACT
A case of vertical transmission in a 35-year-old pregnant woman, gravida 4, para 2 with an unknown medical history of carrying primary syphilis is described. A routine 3rd trimester scan was performed at 30 + 5 weeks of pregnancy, which revealed fetal growth restriction (FGR) associated with absent fetal movement, a pathologic neuroscan characterized by cortical calcifications and ominous Doppler waveform analysis of the umbilical artery and ductus venosus. Computerized electronic fetal monitoring (EFM) showed a Class III tracing, according to the American College of Obstetricians and Gynecologists (ACOG) guidelines. An emergency C-section was performed and a female newborn weighing 1470 g was delivered. The Apgar scores were 5 and 8 at the first and fifth min, respectively. Besides the prompted obstetrical and neonatal interventions, the neonate died after 7 days. A histologic examination of the placenta revealed a chorioamnionitis at stage 1/2 and grade 2/3. The parenchyma showed diffuse delayed villous maturation, focal infarcts, and intraparenchymal hemorrhages. The decidua presented with chronic deciduitis with plasma cells. The parents declined the autopsy. Congenital syphilis is an emerging worldwide phenomenon and the multidisciplinary management of the mother and the fetus should be mandatory.
Subject(s)
COVID-19 Drug Treatment , COVID-19/therapy , Oxygen Inhalation Therapy/methods , SARS-CoV-2 , Adult , COVID-19/diagnosis , COVID-19/physiopathology , Combined Modality Therapy , Female , Fetal Monitoring/methods , Humans , Immunization, Passive/methods , Monitoring, Physiologic/methods , Pregnancy , SARS-CoV-2/immunology , SARS-CoV-2/isolation & purification , Treatment Outcome , COVID-19 SerotherapyABSTRACT
INTRODUCTION: Blake's pouch cyst (BPC) represents an abnormal development of the posterior membranous area of the fetal brain. MATERIAL AND METHODS: Two- and three-dimensional ultrasound with Cristal and Realistic Vue were used to characterized the early prenatal diagnosis. RESULTS: At 9 weeks and 5 days a ballooning in the posterior fossa and resulting in an enlarged intracranial translucency (IT) was detected by 3D ultrasound using Cristal Vue in "inversion" mode and Cristal plus Realistic Vue. In addition, an increased nuchal translucency (7 mm) due to septated cystic hygroma (SCHy) was an associated finding. Hydrops fetalis ensued and a chorionic villus sampling at 12 weeks revealed a 45,X monosomy with persisting BPC. Follow up scan were planned fortnightly. A spontaneous miscarriage occurred at 16 weeks. CONCLUSION: Three-dimensional ultrasound with Cristal and Realistic Vue aided the prenatal diagnosis of BPC in the first trimester.
Subject(s)
Central Nervous System Cysts/diagnostic imaging , Early Diagnosis , Imaging, Three-Dimensional/methods , Ultrasonography, Prenatal/methods , Female , Humans , Pregnancy , Pregnancy Trimester, FirstABSTRACT
INTRODUCTION: Ablation of the acardiac twin umbilical cord in the TRAP protects the normal donor twin. MATERIALS AND METHODS: Two case descriptions, one of interstitial laser photocoagulation and one of laser umbilical cord occlusion (L-UCO) of the acardiac twin in monochorionic monoamniotic pregnancies are reported. RESULTS: L-UCO in two pregnancies with TRAP syndrome in the second trimester resulted in intrauterine fetal death in both cases after 1 month. Case 1 had no detectable cause of fetal death. Case 2 had rupture of the amniotic sac causing anhydramnios and acute chorioamnionitis. A groove on the umbilical cord of the normal twin indicated a cord stricture due to cord entanglement. CONCLUSION: Our experience confirms that the best timing and optimal treatment of MC/MA twins complicated by TRAP sequence still remains a controversial clinical issue. Cord entanglement may continue be a potential clinical risk factor for adverse perinatal outcome even after ablation therapy.
Subject(s)
Fetofetal Transfusion/surgery , Fetoscopy/methods , Laser Coagulation/methods , Laser Therapy/methods , Female , Humans , Pregnancy , Twins, MonozygoticABSTRACT
We describe a previously unreported case of immature teratoma originating from the tela chorioidea of the third ventricle diagnosed during labor at term of pregnancy. Postnatal MR imaging and pediatric neurosurgery with postnatal outcome at 6 months of age are reported.