Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 7 de 7
Filter
1.
Eur Rev Med Pharmacol Sci ; 19(19): 3548-55, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26502842

ABSTRACT

OBJECTIVE: Iliac crest bone graft (ICBG) is considered the gold standard for spine surgical procedures to achieve a successful fusion, because of its known osteoinductive and osteoconductive properties. Considering its autogenous origin, the use of ICBG has not been associated to an increase of intraoperative or postoperative complications directly related to the surgery. However, complications related to the harvesting procedure and to the donor site morbidity have been largely reported in the literature, favoring the development of a wide range of alternative products to be used as bone graft extenders or substitutes for spine fusion. The family of ceramic-based bone grafts has been widely used and studied during the last years for spine surgical procedures in order to reduce the need for iliac crest bone grafting and the consequent morbidity associated to the harvesting procedures. PATIENTS AND METHODS: We report here the results of a post-market surveillance analysis performed on four independent cohorts of patients (115 patients) to evaluate the safety of three different formulations of hydroxyapatite-derived products used as bone graft extenders/substitutes for lumbar arthrodesis. RESULTS: No intraoperative or post-operative complications related to the use of hydroxyapatite-derived products were detected, during medium and long follow up period (minimum 12 months-maximum 5 years). CONCLUSIONS: This post-market surveillance analysis evidenced the safety of ceramic products as bone graft extenders or substitutes for spine fusion. Moreover, the evidence of the safety of hydroxyapatite-derived products allows to perform clinical studies aimed at evaluating the fusion rates and the clinical outcomes of these materials as bone graft extenders/substitutes, in order to support their use as an alternative to ICBG for spine fusion.


Subject(s)
Bone Transplantation/methods , Durapatite/therapeutic use , Ilium/transplantation , Lumbosacral Region/surgery , Product Surveillance, Postmarketing/methods , Spinal Fusion/methods , Adult , Aged , Aged, 80 and over , Bone Transplantation/adverse effects , Cohort Studies , Female , Humans , Male , Middle Aged
2.
Cephalalgia ; 27(10): 1171-3, 2007 Oct.
Article in English | MEDLINE | ID: mdl-17655718

ABSTRACT

Thunderclap headache is well known to be a presenting feature of a variety of causal events. Indeed, a primary form is considered in the International Classification of Headache Disorders-II, but such diagnosis must be made only after exclusion of a possible secondary cause. We report a case of late-onset idiopathic aqueductal stenosis presenting with thunderclap headache, in the absence of abnormal neurological findings or indirect signs of raised intracranial pressure. The patient recovered completely after endoscopic third ventriculostomy. This case indicates primary aqueduct stenosis as a possible, never previously reported, cause of thunderclap headache.


Subject(s)
Cerebral Aqueduct/pathology , Headache Disorders, Primary/etiology , Hydrocephalus/complications , Adult , Cerebral Aqueduct/surgery , Constriction, Pathologic/complications , Female , Headache Disorders, Primary/surgery , Humans , Hydrocephalus/surgery , Magnetic Resonance Imaging , Third Ventricle/pathology , Third Ventricle/surgery , Ventriculostomy
3.
J Neurosurg Sci ; 42(4): 227-32, 1998 Dec.
Article in English | MEDLINE | ID: mdl-10404751

ABSTRACT

The authors present a case of a patient wounded to the head and back by civilian firearm projectiles. The case peculiarity is that only one bullet reached the brain stem level causing significant neurological deficits. The final clinical picture is comparable to the "caudal pontine tegmentum syndrome". The authors describe both the bullet path and the intracranial localization taking into account ballistic details. The problems associated with prognosis, diagnosis, and treatment for gunshot wounds are discussed. In addition, the authors explain the main intracranial lesions and their mechanisms, the role of investigation, and the protocol of medical and surgical treatment. Lastly, a systematic approach for treating these types of gunshot wounds is outlined.


Subject(s)
Brain Stem/injuries , Craniocerebral Trauma/etiology , Wounds, Gunshot , Anti-Bacterial Agents/therapeutic use , Brain Stem/diagnostic imaging , Craniocerebral Trauma/diagnosis , Craniocerebral Trauma/drug therapy , Humans , Male , Middle Aged , Nervous System Diseases/etiology , Preventive Medicine/methods , Scalp/pathology , Tomography, X-Ray Computed , Wounds, Gunshot/complications , Wounds, Gunshot/diagnosis , Wounds, Gunshot/drug therapy , Wounds, Gunshot/pathology
5.
J Comput Assist Tomogr ; 15(6): 1074-6, 1991.
Article in English | MEDLINE | ID: mdl-1658094

ABSTRACT

Attempts have been made to overcome the limited visibility of anatomic structures on axial CT by direct multiplanar sections or multiplanar reformatted views. So as not to be restricted by "planar cuts," we have used curved coronal reformatting to investigate some of the cranial structures, whose tortuous anatomy cannot be visualized entirely with standard CT. In fact, we have provided a "flattened" presentation of the optic nerve and chiasma, facial nerve canal, and jugular foramen, showing them in their entire extension. Despite the geometrical deformation produced by this technique, its potential to depict the anatomy of some structures is noteworthy.


Subject(s)
Image Processing, Computer-Assisted/methods , Skull Neoplasms/diagnostic imaging , Skull/diagnostic imaging , Tomography, X-Ray Computed/methods , Glomus Tumor/diagnostic imaging , Humans , Reference Values , Software
SELECTION OF CITATIONS
SEARCH DETAIL
...