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1.
Front Cardiovasc Med ; 9: 1060813, 2022.
Article in English | MEDLINE | ID: mdl-36483627

ABSTRACT

Endothelial Growth Factor Receptor (EGFR) mutations are frequently found among NSCLC patients. Second-generation Tyrosine Kinase Inhibitor (TKI) Afatinib is frequently used in this population of patients achieving better results than cytotoxic chemotherapy in terms of survival and progression. Afatinib-related cardiotoxicity has been rarely reported. Here we comment on a clinical case of a Takotsubo Cardiomyopathy Afatinib-induced in an NSCLC patient.

2.
Int J Syst Evol Microbiol ; 70(5): 3379-3390, 2020 May.
Article in English | MEDLINE | ID: mdl-32375944

ABSTRACT

During a survey of fungi in native forests in Chile, several unidentified isolates of Diaporthe were collected from different hosts. The isolates were characterized based on DNA comparisons, morphology, culture characteristics and host affiliation, in accordance with previous descriptions. Phylogenetic analysis of the ITS region, combined with partial tub2 and tef1 genes, showed that the isolates formed three distinct groups representing three new taxa. The three new species of Diaporthe, Diaporthe araucanorum on Araucaria araucana, Diaporthe foikelawen on Drimys winteri and Diaporthe patagonica on Aristotelia chilensis are described and illustrated in the present study.


Subject(s)
Forests , Phylogeny , Saccharomycetales/classification , Chile , DNA, Fungal/genetics , DNA, Ribosomal Spacer/genetics , Genes, Fungal , RNA, Ribosomal, 16S/genetics , Saccharomycetales/isolation & purification , Sequence Analysis, DNA
3.
Nano Lett ; 15(10): 6419-28, 2015 Oct 14.
Article in English | MEDLINE | ID: mdl-26375710

ABSTRACT

Quantum effects in plasmonic systems play an important role in defining the optical response of structures with subnanometer gaps. Electron tunneling across the gaps can occur, altering both the far-field optical response and the near-field confinement and enhancement. In this study, we experimentally and theoretically investigate plasmon coupling in gold "nanomatryoshka" (NM) nanoparticles with different core-shell separations. Plasmon coupling effects between the core and the shell become significant when their separation decreases to 15 nm. When their separation decreases to below 1 nm, the near- and far-field properties can no longer be described by classical approaches but require the inclusion of quantum mechanical effects such as electron transport through the self-assembled monolayer of molecular junction. In addition, surface-enhanced Raman scattering measurements indicate strong electron-transport induced charge transfer across the molecular junction. Our quantum modeling provides an estimate for the AC conductances of molecules in the junction. The insights acquired from this work pave the way for the development of novel quantum plasmonic devices and substrates for surface-enhanced Raman scattering.

4.
Opt Express ; 23(6): 8134-49, 2015 Mar 23.
Article in English | MEDLINE | ID: mdl-25837151

ABSTRACT

Electron tunneling through narrow gaps between metal nanoparticles can strongly affect the plasmonic response of the hybrid nanostructure. Although quantum mechanical in nature, this effect can be properly taken into account within a classical framework of Maxwell equations using the so-called Quantum Corrected Model (QCM). We extend previous studies on spherical cluster and cylindrical nanowire dimers where the tunneling current occurs in the extremely localized gap regions, and perform quantum mechanical time dependent density functional theory (TDDFT) calculations of the plasmonic response of cylindrical core-shell nanoparticles (nanomatryushkas). In this axially symmetric situation, the tunneling region extends over the entire gap between the metal core and the metallic shell. For core-shell separations below 0.5 nm, the standard classical calculations fail to describe the plasmonic response of the cylindrical nanomatryushka, while the QCM can reproduce the quantum results. Using the QCM we also retrieve the quantum results for the absorption cross section of the spherical nanomatryushka calculated by V. Kulkarni et al. [Nano Lett. 13, 5873 (2013)]. The comparison between the model and the full quantum calculations establishes the applicability of the QCM for a wider range of geometries that hold tunneling gaps.

5.
Sci Adv ; 1(11): e1501095, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26824066

ABSTRACT

The ability of localized surface plasmons to squeeze light and engineer nanoscale electromagnetic fields through electron-photon coupling at dimensions below the wavelength has turned plasmonics into a driving tool in a variety of technological applications, targeting novel and more efficient optoelectronic processes. In this context, the development of active control of plasmon excitations is a major fundamental and practical challenge. We propose a mechanism for fast and active control of the optical response of metallic nanostructures based on exploiting quantum effects in subnanometric plasmonic gaps. By applying an external dc bias across a narrow gap, a substantial change in the tunneling conductance across the junction can be induced at optical frequencies, which modifies the plasmonic resonances of the system in a reversible manner. We demonstrate the feasibility of the concept using time-dependent density functional theory calculations. Thus, along with two-dimensional structures, metal nanoparticle plasmonics can benefit from the reversibility, fast response time, and versatility of an active control strategy based on applied bias. The proposed electrical manipulation of light using quantum plasmonics establishes a new platform for many practical applications in optoelectronics.

6.
Adicciones ; 24(1): 69-75, 2012.
Article in Spanish | MEDLINE | ID: mdl-22508019

ABSTRACT

Assessment of a methadone substitution and maintenance treatment program in Colombia using the OTI (Opiate Treatment Index) instrument. Descriptive study with a 50-patient sample attended in the period 2007- 2008 for their heroin addiction. The OTI instrument was implemented to assess drug use, HIV risk-taking behavior, social functioning, criminality, health status and psychological functioning. Men accounted for 74% of the sample, women for 26%. Mean age was 22, with 64% in the 20-24 age group. Mean reported age at onset of heroin use was 18, with a range of 13-28. In 38% of the sample (19 patients) comorbidity with other mental disorders was found, 47% of these being personality disorders. Median reported current methadone dose was 40 mg/day, with a range of 15-80 mg/day. According to the OTI subscales, HIV risk-taking behavior was low-moderate, while social functioning, criminality and health status were low-risk. In the case of psychological adjustment, a low-moderate risk score was obtained for the 0-12 month treatment group, and a moderate risk score for the 12-24 and ≥ 24 month groups. Starting age for heroin use in this population is early . In general, the risk assessed in the OTI areas is low, possibly due to problematic heroin use being in its early stages in Colombia, but comorbidity with personality disorders is high.


Subject(s)
Heroin Dependence/drug therapy , Methadone/therapeutic use , Narcotics/therapeutic use , Opiate Substitution Treatment , Colombia , Female , Humans , Male , Program Evaluation , Young Adult
7.
Adicciones (Palma de Mallorca) ; 24(1): 69-76, ene.-mar. 2012. graf, tab
Article in Spanish | IBECS | ID: ibc-101306

ABSTRACT

Evaluación de un programa de tratamiento de sustitución y mantenimiento con metadona en Colombia mediante aplicación del instrumento OTI (Opiate Treatment Index). Estudio descriptivo que utiliza muestra de 50 pacientes atendidos en 2007-2008 para la adicción a heroína. Con el instrumento OTI se evalúan áreas de consumo de drogas, conductas de riesgo para el contagio de VIH, funcionamiento social, actividad delictiva, estado de salud y ajuste psicológico. El 74% de la muestra son hombres y 26% mujeres, con edad media 22 años (64% pertenece al grupo 20-24 años). La edad de inicio en el consumo de heroína es 18 años (rango entre 13 y 28). En el 38% (19 de 50) se encontró comorbilidad con otros trastornos mentales, siendo el 47% trastornos de personalidad. La dosis actual de metadona es 40 mg/día, rango entre 15 y 80 mg/día. Las escalas del instrumento OTI muestran conducta de riesgo para VIH en nivel Bajo-Medio funcionamiento social, escala delictiva y estado de salud riesgo Bajo; la escala de ajuste psicológico muestra riesgo Bajo-Medio en el grupo 0-12 meses y Medio en los grupos 12-24 y >24 meses; para todas las diferencias entre grupos y riesgos no se encontró significancia estadística .El consumo de heroína en esta población inicia a edad temprana. En general el riesgo evaluado en las diferentes áreas del OTI es bajo, posiblemente por la etapa inicial de consumo problemático de heroína en Colombia. Existe alta comorbilidad con trastornos de personalidad (AU)


Assessment of a methadone substitution and maintenance treatment program in Colombia using the OTI (Opiate Treatment Index) instrument. Descriptive study with a 50-patient sample attended in the period 2007-2008 for their heroin addiction. The OTI instrument was implemented to assess drug use, HIV risk-taking behavior, social functioning, criminality, health status and psychological functioning. Men accounted for 74% of the sample, women for 26%. Mean age was 22, with 64% in the 20-24age group. Mean reported age at onset of heroin use was 18, with a range of 13-28. In 38% of the sample (19 patients) comorbidity with other mental disorders was found, 47% of these being personality disorders. Median reported current methadone dose was 40 mg/day, with a range of 15-80 mg/day. According to the OTI subscales, HIV risk-taking behavior was low-moderate, while social functioning, criminality and health status were low-risk. In the case of psychological adjustment, a low-moderate risk score was obtained for the 0-12 month treatment group, and a moderate risk score for the12-24 and >24 month groups. Starting age for heroin use in this population is early . In general, the risk assessed in the OTI areas is low, possibly due to problematic heroin use being in its early stages in Colombia, but comorbidity with personality disorders is high (AU)


Subject(s)
Humans , Methadone/therapeutic use , Heroin Dependence/drug therapy , Colombia/epidemiology , Age of Onset , Risk Factors , Diagnosis, Dual (Psychiatry)/statistics & numerical data , Personality Disorders/epidemiology
8.
Adicciones ; 23(1): 17-25, 2011.
Article in Spanish | MEDLINE | ID: mdl-21503560

ABSTRACT

AIMS: To study the risk of pathological gambling and its possible relation with mental disorders and school and family problems in a population of school pupils from the city of Medellin (Colombia), with a view to providing guidance for mental health care. METHOD: Cross-sectional study; sample comprises 3486 students aged 10 to 19 years selected from all the educational institutions in the city. The sample is probabilistic and represents an estimated population of 290,000 young people from Medellin. The SOGS instrument (South Oaks Gambling Screening) was used for screening risk and likelihood of problem gambling. The analytic stage assessed possible associated factors such as mental disorders, alcohol use and drug use, with statistical significance levels of 5% and prevalence rates with 95% confidence intervals. RESULTS: A total of 48.6% were without problems, 37.6% were at risk and 13.8% were possible pathological gamblers. Males were more at risk than females (2.5:1), and the highest proportion of possible pathological gamblers was in the 10-14 age group (58.7%), vs. the 15-19 group (41.3%). Pathological gambling in young people is associated in this study with: anxiety OR=2.1(1.69-2.60), depression OR=1.73(1.33-2.24), suicide attempt OR=1.85(1.20-2.85), impulsivity OR=3.48(2.85-4.26), violent behavior OR=4.64(3.57-5.58), and problems at school OR=2.46(1.97-3.06); recent use of cigarettes, drunkenness and illegal drugs (use/addiction) were identified as associated risk factors, p value: <0.05. CONCLUSIONS: Pathological gambling risk is high in this young population, and is associated with mental disorders, use of psychoactive substances, and school and family problems. This situation suggests the need for large-scale and comprehensive preventive and therapeutic intervention measures for addressing the problem.


Subject(s)
Gambling/epidemiology , Adolescent , Child , Colombia , Cross-Sectional Studies , Female , Gambling/complications , Humans , Male , Mental Disorders/complications , Multivariate Analysis , Risk Factors , Young Adult
9.
Adicciones (Palma de Mallorca) ; 23(1): 17-26, ene.-mar. 2011. graf, tab
Article in Spanish | IBECS | ID: ibc-86558

ABSTRACT

Objetivos: Investigar el riesgo de juego patológico y su posible relación con trastornos mentales, problemas escolares y familiares, en una población escolarizada de la ciudad de Medellín (Colombia), para orientar la atención en salud mental. Método: Estudio de corte transversal; muestra de 3.486 estudiantes de 10 a 19 años, probabilística y representativa de una población de 290.000 jóvenes. El instrumento SOGS (South Oaks Gambling Screening), fue utilizado para evaluar el riesgo y probabilidad de juego patológico; en etapa analítica se evaluó la posible asociación con trastornos mentales, uso de alcohol y drogas para juego patológico, descritas con significancia estadística de 5% y proporciones de prevalencia con intervalos de confianza del 95%.Resultados: 48,6% sin problemas, 37,6% están en riesgo y 13,8% son posibles jugadores patológicos. Hombres tienen mayor riesgo que las mujeres (2,5:1) y la mayor proporción de posibles jugadores patológicos pertenecen al grupo de 10-14 años (58,7%) vs. 15-19 (41,3%). El Juego Patológico presenta asociación con ansiedad RD=2,1(1,69-2,60), depresión RD=1,73(1,33-2,24), intento de suicidio RD=1,85(1,20-2,85), impulsividad RD=3,48(2,85-4,26), comportamiento violento RD=4,64(3,57-5,58), problemas en la escuela RD=2,46(1,97-3,06); el uso de cigarrillo, alcohol hasta la embriaguez y el uso-adicción a drogas ilegales, se identificaron como factores asociados con valores de p<0,05. Conclusiones: La prevalencia de riesgo de juego patológico es alta para esta población y está asociada con trastornos mentales, consumo de sustancias psicoactivas y problemas en la relación familiar y escolar; esta situación señala la necesidad de generar un despliegue amplio e integral de intervención preventiva y terapéutica para impactar el problema (AU)


Aims: To study the risk of pathological gambling and its possible relation with mental disorders and school and family problems in a population of school pupils from the city of Medellin (Colombia), with a view to providing guidance for mental health care. Method: Cross-sectional study; sample comprises 3486 students aged 10to 19 years selected from all the educational institutions in the city. The sample is probabilistic and represents an estimated population of 290,000young people from Medellin. The SOGS instrument (South Oaks Gambling Screening) was used for screening risk and likelihood of problem gambling. The analytic stage assessed possible associated factors such as mental disorders, alcohol use and drug use, with statistical significance levels of 5% and prevalence rates with 95% confidence intervals. Results: A total of 48.6% were without problems, 37.6% were at risk and 13.8% were possible pathological gamblers. Males were more at risk than females (2.5:1), and the highest proportion of possible pathological gamblers was in the 10-14 age group (58.7%), vs. the 15-19 group (41.3%).Pathological gambling in young people is associated in this study with: anxiety OR=2.1(1.69-2.60), depression OR=1.73(1.33-2.24), suicide attempt OR=1.85(1.20-2.85), impulsivity OR=3.48(2.85-4.26), violent behavior OR=4.64(3.57-5.58), and problems at school OR=2.46(1.97-3.06); recent use of cigarettes, drunkenness and illegal drugs (use/addiction) were identified as associated risk factors, p value: <0.05. Conclusions: Pathological gambling risk is high in this young population, and is associated with mental disorders, use of psychoactive substances, and school and family problems. This situation suggests the need for larges cale and comprehensive preventive and therapeutic intervention measures for addressing the problem (AU)


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Mental Disorders/epidemiology , Mental Disorders/pathology , Colombia/epidemiology , Mental Health , Alcoholism/epidemiology , Anxiety/diagnosis , Anxiety/epidemiology , Depression/epidemiology , Suicide, Attempted/psychology
10.
Rev. MVZ Córdoba ; 13(3): 1486-1494, sep.-dic. 2008. ilus, tab
Article in Spanish | LILACS, COLNAL | ID: lil-637123

ABSTRACT

Objetivo. Determinar la frecuencia de hemoparásitos en los bovinos evaluados por microscopía directa. Materiales y métodos. Se aplicó un modelo epidemiológico cuyo diseño de investigación fue transeccional de tipo descriptivo retrospectivo transversal. Se analizó la totalidad de los datos de los últimos 5 años, proporcionados por el laboratorio Lavebac que presta su servicio a las regiones del Bajo Cauca Antioqueño y Córdoba. Se realizó un análisis de tendencias por el tipo de parásito, sistema de explotación, procedencia y época climática; seguido de un análisis comparativo de asociación utilizando la razón de disparidad (RD) y el X², mediante el programa EPI-INFO versión 3.3. Resultados. Se encontró una frecuencia hemoparasitaria del 22.5%, y de estos el 59.3% correspondió a Anaplasma sp, el 3.1% a Babesia sp y para Trypanosoma sp 30.9%. La región con mayor frecuencia hemoparasitaria fue Bajo Cauca (14%); los diagnósticos positivos fueron realizados con mayor frecuencia en época seca (14.9%), en la que se detectó mayor proporción de infección por Anaplasma sp. Conclusiones. Los resultados dan una aproximación a la frecuencia y distribución de Trypanosoma sp, Babesia sp y Anaplasma sp en dos zonas ganaderas de Colombia, en donde durante la época seca se encontró un mayor porcentaje de infección, y de los agentes hemoparasitarios Anaplasma sp es el más frecuente.


Objective. To determine the frequency of hemoparasites in bovines evaluated by direct microscopy. Materials and methods. A descriptive retrospective cross study was carried out. All the data of the last 5 years from the Lavebac laboratory was analyzed. This laboratory offers its services in the Cauca-Medio Antioqueño and the Department of Cordoba. A frequency analysis was conducted, taking into consideration the type of parasite, the type of cattle operation, origin and season. Comparative analyses using odds ratios were conducted using EPIINFO, version 3.3. Results. The frequency of hemoparasitism was 22.5%. Of these 59.3% of parasites were Anaplasma sp, 3.1% were Babesia sp and 30.9% were Trypanosoma sp. The positive diagnostics occurred more frequently in the dry season (14.9%) in which a higher frequency of infection by Anaplasma sp. was detected. Conclusions. These results allow an approximation to the frequency and distribution of Trypanosoma sp, Babesia sp and Anaplasma sp in two cattle raising regions of Colombia. A higher percentage of hemoparasite infection was found during the dry season, and Anaplasma sp was the most frequent of parasite.


Subject(s)
Epidemiology , Anaplasma , Babesia , Colombia , Trypanosoma
11.
Am J Trop Med Hyg ; 77(1): 67-72, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17620632

ABSTRACT

Accurate identification of anopheline species is essential for vector incrimination and implementation of appropriate control strategies. Several anopheline species are considered important malaria vectors in Colombia; however, species determination is complicated by cryptic morphology and intra-individual variation. We describe polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) of internal transcribed spacer 2 (ITS2) sequences for differentiation of seven Anopheles species collected in a locality in Antioquia, Colombia, with high levels of malaria transmission. Each of these seven species can be identified by unique AluI PCR-RFLP restriction patterns. Comparisons of morphologic identification with molecular identification of voucher specimens confirmed species designation for 886 wild-caught anophelines. This new method can be used as a diagnostic tool for discrimination of anopheline species of medical importance in this region, some of which have overlapping morphologic characters and for conducting complementary studies where rapid and accurate identification of large numbers of specimens is needed.


Subject(s)
Anopheles/genetics , Genes, Insect/genetics , Insect Vectors/genetics , Malaria/transmission , Polymorphism, Restriction Fragment Length , Animals , Anopheles/classification , Colombia , Insect Vectors/classification , Malaria/prevention & control , Mosquito Control , Predictive Value of Tests
12.
Rev. chil. cardiol ; 23(4): 337-342, oct.-dic. 2004. tab
Article in Spanish | LILACS | ID: lil-419192

ABSTRACT

Introducción: La aspirina se usa frecuentemente para la prevención y tratamiento de eventos isquémicos cardiovasculares. Estudios en población anglosajona han mostrado que entre 5-9 por ciento de los pacientes presentan resistencia total a la acción antiplaquetaria de aspirina. Objetivos: Conocer la prevalencia de resistencia a aspirina en enfermos cardiovasculares chilenos. Evaluar factores asociados a la resistencia. Pacientes y Métodos: Se estudian 68 pacientes (21 mujeres, ± 10 años) con enfermedades cardiovasculares estables usuarios de aspirina (100-325 mg/día). Se evalúan variables clínicas y de coagulación básica. Se estudió la agregación plaquetaria con agregómetro óptico en plasma rico en plaquetas con 3 agonista. Se definió Resistencia Total a la aspirina como. 1) agregación (20 por ciento con ácido araquidónico y 2) agregación > 70 por ciento con ADP y/o colágeno. Resultados: Siete pacientes (10,3 por ciento, IC 95 por ciento = 4,2-20,1 por ciento) cumplieron ambos criterios y se consideraron como resistentes totales, 34 (50 por ciento, IC 95 por ciento = 37,6-62,4 por ciento) cumplieron con sólo un criterio y se consideraron como resistentes parciales, y los 27 pacientes restantes (39,7 por ciento, IC 95 por ciento = 28,0-52,3 por ciento) no cumplieron con ninguno de los criterios y se clasificaron como respondedores a AAS. Hubo una mayor frecuencia de fumadores (55,6 vs 23,7 por ciento) en los pacientes con Resistencia Total, pero no alcanzó significación estadística (p = 0,06). Conclusiones: La mayoría de los pacientes cardiovasculares presentan algún grado de resistencia al AAS y un 10,3 por ciento presentan Resistencia Total. No encontramos diferencias significativas entre los los pacientes con y sin resistencia total a aspirina.


Subject(s)
Humans , Male , Female , Middle Aged , Aspirin/therapeutic use , Drug Resistance , Cardiovascular Diseases/drug therapy , Adenosine Diphosphate , Arachidonic Acid , Platelet Aggregation , Aspirin/administration & dosage , Aspirin/agonists , Aspirin/blood , Chile , Collagen , Dose-Response Relationship, Drug , Bleeding Time/methods
13.
Rev Med Chil ; 131(10): 1101-10, 2003 Oct.
Article in Spanish | MEDLINE | ID: mdl-14692298

ABSTRACT

BACKGROUND: Intraventricular resynchronization with pacemakers is a promising therapy for patients with refractory cardiac failure and intraventricular conductions delay. However its long term effects are not well known. AIM: To report the results of this therapy in patients with cardiac failure. PATIENTS AND METHODS: Fourteen patients (11 male), whose mean age was 68 years, with a severe and refractory cardiac failure, have been treated in our unit using intraventricular resynchronization with pacemakers. Eight had a coronary heart disease and six a dilated myocardiopathy. The pacemaker was implanted transvenously, with conventional stimulation in atrium and right ventricle. The left ventricle was stimulated through an epicardial vein, accessed through the coronary sinus. RESULTS: In one patient the high thresholds did not allow a left ventricular stimulation. In the other 13 patients, a clinical improvement was observed in 11 (85%), that has been sustained for a mean of 8.2 months. The ejection fraction improved form 23.5 to 32.4% (p < 0.001), the 6 min walking test improved from 347 to 437 m (p = 0.003) and the functional capacity changes from 3.3 to 2.7 (p < 0.001). Three patients died during follow up. One was the patient in whom the stimulation failed and two had a sudden death. No complications of the procedure were observed. CONCLUSIONS: In this series, intraventricular resynchronization with pacemakers was effective in 11 of 13 patients, improving functional capacity and ejection fraction. Sudden death could be avoided adding a defibrillator to the pacemaker system.


Subject(s)
Cardiac Pacing, Artificial/methods , Cardiomyopathy, Dilated/therapy , Aged , Aged, 80 and over , Coronary Disease/therapy , Female , Humans , Male , Middle Aged , Pacemaker, Artificial , Stroke Volume , Treatment Outcome , Ventricular Dysfunction/physiopathology
14.
Bol. Hosp. San Juan de Dios ; 44(4): 209-15, jul.-ago. 1997. tab
Article in Spanish | LILACS | ID: lil-202623

ABSTRACT

Las acciones médicas son fuente potencial de complicaciones, sobre todo en la medicina actual cada vez más intervencionista.Se desconoce con precisión, la magnitud y gravedad de éstas complicaciones motivo por el cual se diseño en el Servicio de Medicina interna del Hospital San Juan de Dios un estudio retrospectivo durante un período 6 meses seleccionando, entre todos los pacientes ingresados los que padecían algún problema iatrogénico sea medicamentoso o de otra índole. El 7,5 por ciento de los pacientes ingresados durante el período de estudio presentaron alguna complicación durante su hospitalización. En el 5,2 por ciento de los casos ello se debió a reacciones adversas a medicamentos (antibióticos en su mayoría). En el 1,3 por ciento de los pacientes la complicación fue secundaria a la realización de procedimientos diagnósticos o terapéuticos. En el 64,7 por ciento de los casos se trató de infecciones nosocomiales, siendo la más frecuente de ellas la neumonía. De los paciente afectados por complicaciones y que fallecieron durante su hospitalización, los dos tercios de ellos tenían relación indirecta con las complicaciones, mayoritariamente infecciosas). Este estudio es un primer intento por definir nuestra patología iatrogénica, cuyo mejor conocimiento debe llevar necesariamente a prevenir las complicaciones y iatrogenias que ocurren en el curso de las hospitalizaciones y, por ende, a mejorar la calidad de la atención que otorgamos a nuestros pacientes. La disminución del número de iatrogenias determina un acortamiento de los días de estada y una economía de insumos y en especial de medicamentos


Subject(s)
Humans , Iatrogenic Disease/epidemiology , Hospitalization/statistics & numerical data , Acinetobacter/isolation & purification , Drug Therapy/adverse effects , Hospital Mortality , Cross Infection/etiology , Klebsiella pneumoniae/isolation & purification , Retrospective Studies , Staphylococcus aureus/isolation & purification
15.
Bol. Hosp. San Juan de Dios ; 44(4): 255-6, jul.-ago. 1997. tab
Article in Spanish | LILACS | ID: lil-202636
16.
Educ. méd. contin ; (53): 8-11, dic. 1996. tab
Article in Spanish | LILACS | ID: lil-188628

ABSTRACT

Se estudiaron 84 pacientes que fueron referidas a la Clinica de Ospeoporosis, las mismas que presentaron edades entre 30 y 76 años, con una edad promedio de 55 años a estas pacientes se les realizó valoraciones de velocidad de transmición del sonido (SOS) en tibia derecha, mediante el sistema "Sundscan 2000" de Myrid Ultrasound Systems Ltda. y densitometria ósea (BMD) por medio de un equipo DPX de lunar Co. Los resultados, expresados como "T" score y "Z" score respectivamente, se compararon para establecer tanto su sensibilidad como su especificidad y valores predictivos.


Subject(s)
Humans , Bone Density , Densitometry , Recruitment Detection, Audiologic , Sound , Outflow Velocity Measurement , Femur , Lumbosacral Region , Tibia
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