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1.
An. sist. sanit. Navar ; (Monografía n 8): 177-194, Jun 23, 2023. tab
Article in Spanish | IBECS | ID: ibc-222472

ABSTRACT

La identificación temprana de clusters de población trabajadora infectada por el nuevo virusSARS-Cov-2 tras la declaración de la situación de pandemia para la COVID-19 desde la OMS,alarmó al mundo del trabajo y alertó en especial a las administraciones públicas responsablesde la salud laboral. En este artículo compartimos la experiencia del Servicio de Salud Laboral (SSL) del Institutode Salud Pública y Laboral de Navarra (ISPLN) con numerosas, y diversas actuaciones desa-rrollada frente a la COVID-19 en el ámbito ocupacional. El SSL fue identificando y respondiendoa las necesidades detectadas cotidianamente desde el seguimiento de las publicaciones deotras instituciones, de la bibliografía científica y, de forma importante, de las demandas ypreocupaciones expresadas por los agentes laborales, direcciones de las empresas, personaltrabajador y sus representantes y organizaciones sindicales.Se desarrollaron intervenciones preventivas, normativas, asistenciales, organizativas, de ges-tión y de investigación. Además de abordar las necesidades del conjunto de la población labo-ral, el SSL centró sus esfuerzos en los colectivos más vulnerables. La pertenencia del SSL y de los servicios de Vigilancia Epidemiológica y de Promoción deSalud del ISPLN a la misma institución (Departamento de Salud) ha facilitado muchas actuacio-nes. La pertenencia de la Inspección Médica de Servicio Público de Salud al SSL del ISPLN hapermitido responder rápidamente a las necesidades de apoyo precisadas tanto por AtenciónPrimaria de Salud como la parte de la población trabajadora especialmente vulnerable a lainfección. Navarra en el ámbito de la salud laboral cuenta así con una estructura institucionalclaramente diferente a la del resto de comunidades autónomas.(AU)


Subject(s)
Humans , Pandemics , Coronavirus Infections/epidemiology , Occupational Health , Intersectoral Collaboration , Occupational Risks , Risk Groups , Spain , Public Health , Health Services , Preventive Health Services
2.
Mol Ther ; 22(1): 226-32, 2014 Jan.
Article in English | MEDLINE | ID: mdl-24025752

ABSTRACT

The objective of this study was to evaluate ocular tolerance, safety, and effect on intraocular pressure (IOP) of a topically administered small interfering RNA; SYL040012, on healthy volunteers. The study was an open-label, controlled, single-center study comprised of two intervals that enrolled 30 healthy subjects having IOP below 21 mmHg. SYL040012 was administered to one eye as a single dose to six subjects during interval 1. During interval 2 two different doses of SYL040012 were administered to one eye on a daily basis to two separate groups of 12 subjects each, over a period of 7 days. The contralateral eye was evaluated but not administered and served as control for the tolerance study. SYL040012 was well tolerated locally. No local or systemic adverse events related to the product developed in response to any of the doses studied. SYL040012 was not detected in plasma at any time point. Administration of SYL040012 over a period of 7 days reduced IOP values in 15 out of 24 healthy subjects regardless of the dose used. IOP decrease was statistically significant in response to one of the doses tested and responsiveness to SYL040012 seemed to be greater in individuals with higher baseline IOP.


Subject(s)
Intraocular Pressure/genetics , RNA, Small Interfering/genetics , Receptors, Adrenergic, beta-2/genetics , Adolescent , Adult , Drug Administration Schedule , Female , Humans , Male , Ophthalmic Solutions/administration & dosage , RNA Interference , RNA, Small Interfering/administration & dosage , RNA, Small Interfering/adverse effects , Receptors, Adrenergic, beta-2/metabolism , Treatment Outcome , Young Adult
3.
Urol Int ; 87(1): 64-9, 2011.
Article in English | MEDLINE | ID: mdl-21829049

ABSTRACT

BACKGROUND: The number of robotic-assisted procedures offered in Spain is rapidly increasing despite a lack of consensus criteria for training and credentialling. OBJECTIVE: This national multicentre study was designed to analyze the different areas of the robotic urological surgery learning curve. MATERIAL AND METHODS: A questionnaire was sent to all 13 urology units in Spain with an active robotics programme requesting information on training and problems encountered. RESULTS: In most centres (n = 11, 84.6%), training programmes were animal-based; cadavers were used at only 2 (15.4%). Proctoring in initial procedures was practiced by 12 groups (92.3%). When initiating the robotics programme, the console was shared at 8 units (61.5%). Prior experience in open and/or laparoscopic surgery was reported by 10 of the groups (76.9%), and experience in open surgery only by 2 (15.4%) or robotic surgery alone by 1 (7.7%). The procedure with which the robotics programme was started in all 13 participating units was radical prostatectomy. The number of cases needed to complete the learning curve for this procedure was 20-25 cases according to 8 (61.5%) surgery teams. CONCLUSIONS: Up until March 26, 2010, 1,692 operations, mostly radical prostatectomies, were conducted using the da Vinci robot in our country.


Subject(s)
Clinical Competence , Education, Medical, Graduate , Learning Curve , Robotics/education , Surgery, Computer-Assisted/education , Urologic Surgical Procedures/education , Curriculum , Health Care Surveys , Humans , Program Development , Program Evaluation , Spain , Surgery, Computer-Assisted/adverse effects , Surveys and Questionnaires , Urologic Surgical Procedures/adverse effects
4.
Actas Urol Esp ; 33(5): 514-21, 2009 May.
Article in Spanish | MEDLINE | ID: mdl-19658304

ABSTRACT

INTRODUCTION: Standard treatment for small renal masses is partial nephrectomy, which has shown oncological results similar to radical nephrectomy. Ablation procedures such as radiofrequency and cryotherapy have recently been developed in order to minimize the side effects of conventional surgical excision. This article reviews radiofrequency ablation. MATERIALS AND METHODS: For this review, a search was made in the Medline database using the term "renal radiofrequency ablation". RESULTS: The different currently marketed systems for delivery of radiofrequency energy are examined. The different delivery approaches (open, laparoscopic, and percutaneous) are described. A trend towards use of the percutaneous approach was seen. Published clinical studies already include patient series with mid-term follow-ups (3 years) showing oncological outcomes similar to conventional resection procedures with fewer complications. CONCLUSIONS: Renal tumor radiofrequency ablation has proved to be an effective treatment with minimal complications. However, it should only be used in selected patients until longer follow-up studies are available.


Subject(s)
Carcinoma, Renal Cell/surgery , Catheter Ablation , Kidney Neoplasms/surgery , Animals , Catheter Ablation/methods , Humans
5.
Actas Urol Esp ; 33(5): 534-43, 2009 May.
Article in Spanish | MEDLINE | ID: mdl-19658307

ABSTRACT

The increasingly common incidental diagnosis of small renal masses (SRMs) (measuring under 4 cm in size) has led to the consideration of applying minimally invasive techniques to deal with them--particularly in view of the high percentage of non-malignant conditions of this size that are radiologically indistinguishable from tumor lesions. Accordingly, laparoscopic access has gained great importance in the management of these masses, in an attempt to lessen the morbidity associated with lumbotomy. Laparoscopic partial nephrectomy (LPN) is an evolving technique in most centers; on one hand it competes with open partial nephrectomy as the technique of choice, and on the other it will compete in the future with the non-excisional management techniques. These latter procedures in turn have become more precise thanks to laparoscopy. Based on a standardized review of the abundant literature on the treatment of SRMs, the present study examines the technical innovations and improvements afforded by the laparoscopic approach, not only for excision purposes but also a vehicle for minimally invasive treatments. Likewise, the requirements of Services of Urology and the improvements that could be introduced in health systems for advancing the application of LPN in the management of SRMs are commented. Progressive fine-tuning of the technique, with improvement of the laparoscopic repertoire and availability of hemostatic agents, will contribute to increase the indications for LPN in the future. The limited frequency of the disorder and the need to optimize the technique will require health care supervisors to centralize this type of pathology in centers with experience in laparoscopy and open partial nephrectomy.


Subject(s)
Kidney Neoplasms/pathology , Kidney Neoplasms/surgery , Laparoscopy , Nephrectomy/methods , Humans , Laparoscopy/adverse effects , Laparoscopy/methods
6.
Actas Urol Esp ; 33(1): 35-42, 2009 Jan.
Article in Spanish | MEDLINE | ID: mdl-19462723

ABSTRACT

INTRODUCTION: The standard treatment of small renal masses is partial nephrectomy, which has showed similar oncologic results when compared with radical nephrectomy. Recently, ablative techniques, including radiofrequency and cryotherapy ablation, has been developed, with the purpose of minimizing adverse effects of standard surgical excision. In this article we review the technique of radiofrequency ablation. MATERIAL AND METHODS: For this review we conducted a search in the Medline database using the terms "renal radiofrequency ablation". RESULTS: The different currently marketed systems for the delivery of radiofrequency energy are examined. The different techniques of delivery (open, laparoscopic and percutaneous) are described; we observe a trend towards the use of the percutaneous method. Among the published clinical studies there are series of patients with midterm follow-up (3 years) that show oncologic outcomes similar to traditional resection techniques, with fewer complications. CONCLUSIONS: Renal tumor radiofrequency ablation has proved an effective therapy with minimal complications. However, it should be used only in selected patients until longer follow-up studies are available.


Subject(s)
Carcinoma, Renal Cell/surgery , Catheter Ablation , Kidney Neoplasms/surgery , Clinical Trials as Topic , Humans
7.
Actas urol. esp ; 33(5): 514-521, mayo 2009. tab
Article in Spanish | IBECS | ID: ibc-60296

ABSTRACT

Introducción: El tratamiento estándar de las masas renales de pequeño tamaño es la nefrectomía parcial, que ha demostrado unos resultados oncológicos semejantes a la nefrectomía radical. Recientemente se han desarrollado técnicas de ablación como la radiofrecuencia y la crioterapia, con el fin de minimizar los efectos secundarios de la resección quirúrgica convencional. En este artículo, revisamos la técnica de ablación mediante radiofrecuencia. Material y métodos: Para esta revisión se ha utilizado la base de datos Medline introduciendo los términos “renal radiofrequencyablation”. Resultados: Se analizan los diferentes sistemas que existen en el mercado para la aplicación de radiofrecuencia. Se describen las técnicas de aplicación (abierta, laparoscópica y percutánea), observando una tendencia clara a la aplicación de forma percutánea. En los estudios clínicos publicados existen ya series de pacientes con seguimientos a medio plazo (3 años) en los que se demuestra unos resultados oncológicos semejantes a los de las técnicas de resección clásicas y con un índice de complicaciones menor. Conclusiones: La ablación de tumores renales con radiofrecuencia ha demostrado ser un tratamiento eficaz y con mínimas complicaciones. Sin embargo, hasta que no existan seguimientos a largo plazo, se debe utilizar únicamente en pacientes seleccionados (AU)


Introduction: Standard treatment for small renal masses is partial nephrectomy, which has shown oncological results similar to radical nephrectomy. Ablation procedures such as radiofrequency and cryotherapy have recently been developed in order to minimize the side effects of conventional surgical excision. This article reviews radiofrequency ablation. Materials and methods: For this review, a search was made in the Medline database using the term “renal radiofrequency ablation”. Results: The different currently marketed systems for delivery of radiofrequency energy are examined. The different delivery approaches (open, laparoscopic, and percutaneous) are described. A trend towards use of the percutaneous approach was seen. Published clinical studies already include patient series with mid-term follow-ups (3 years) showing oncological outcomes similar to conventional resection procedures with fewer complications. Conclusions: Renal tumor radiofrequency ablation has proved to be an effective treatment with minimal complications. However, it should only be used in selected patients until longer follow-up studies are available (AU)


Subject(s)
Humans , Male , Female , Kidney Neoplasms/surgery , Catheter Ablation/methods , Carcinoma, Renal Cell/surgery , Nephrectomy , Cryotherapy/methods , Electrodes , Laparoscopy
8.
Actas urol. esp ; 33(5): 534-543, mayo 2009. tab, ilus
Article in Spanish | IBECS | ID: ibc-60299

ABSTRACT

El incremento en el diagnóstico incidental de masas renales pequeñas (MRP) -menores de 4 cm- ha obligado a considerar tratamientos mínimamente invasivos para las mismas, sobre todo por el alto porcentaje de patologías no malignas indistinguibles de las tumorales radiológicamente. El acceso laparoscópico ha cobrado por tanto una importancia capital en el manejo de dichas masas, en un intento de disminuir la morbilidad de la lumbotomía. La nefrectomía parcial laparoscópica (NPL) es una técnica en evolución en la mayoría de centros que por un lado compite con la nefrectomía parcial abierta como técnica de elección y por otro lado competirá en un futuro con las técnicas no exeréticas. Estas también se han podido desarrollar de una manera más precisa gracias a la laparoscopia. En este artículo pretendemos, basándonos en una revisión estandarizada de la prolífica literatura a cerca del tratamiento de la MRP, revisar las innovaciones tecnológicas y las mejoras técnicas que la vía de abordaje laparoscópica nos va deparando, no solo como técnica exerética, sino como vehículo de tratamientos mínimamente invasivos, remarcando también los requerimientos de los Servicios de Urología y las mejoras que podrían hacerse en los sistemas sanitarios para quela NPL ganara terreno en el tratamiento de la MRP. La progresiva depuración de la técnica y la mejora del arsenal laparoscópico y de agentes hemostasiantes van a incrementarla indicación de NPL en un futuro. La escasa frecuencia de la patología y la necesidad de optimizar la técnica, obligarían a los responsables sanitarios a centralizar esta patología en centros con experiencia en laparoscopia y en nefrectomía parcial abierta (AU)


The increasingly common incidental diagnosis of small renal masses (SRMs)(measuring under 4 cm in size) has led to the consideration of applying minimally invasive techniques to deal with them - particularly in view of the high percentage of non-malignant conditions of this size that are radiologically indistinguishable from tumor lesions. Accordingly, laparoscopic access has gained great importance in the management of these masses, in an attempt to lessen the morbidity associated with lumbotomy. Laparoscopic partial nephrectomy (LPN) is an evolving technique in most centers; on one hand it competes with open partial nephrectomy as the technique of choice, and on the other it will compete in the future with the non-excisional management techniques. These latter procedures in turn have become more precise thanks to laparoscopy. Based on a standardized review of the abundant literature on the treatment of SRMs, the present study examines the technical innovations and improvements afforded by the laparoscopic approach, not only for excision purposes but also a vehicle for minimally invasive treatments. Likewise, the requirements of Services of Urology and the improvements that could be introduced in health systems for advancing the application of LPN in the management of SRMs are commented. Progressive fine-tuning of the technique, with improvement of the laparoscopic repertoire and availability of hemostatic agents, will contribute to increase the indications for LPN in the future. The limited frequency of the disorder and the need to optimize the technique will require health care supervisors to centralize this type of pathology in centers with experience in laparoscopy and open partial nephrectomy (AU)


Subject(s)
Humans , Male , Female , Nephrectomy/methods , Kidney Neoplasms/surgery , Carcinoma, Renal Cell/surgery , Laparoscopy/methods , Incidental Findings , Minimally Invasive Surgical Procedures/methods
9.
Actas urol. esp ; 33(1): 35-42, ene. 2009. tab
Article in Spanish | IBECS | ID: ibc-115010

ABSTRACT

Introducción: El tratamiento estándar de las masas renales de pequeño tamaño es la nefrectomía parcial, que ha demostrado unos resultados oncológicos semejantes a la nefrectomía radical. Recientemente se han desarrollado técnicas de ablación como la radiofrecuencia y la crioterapia, con el fin de minimizar los efectos secundarios de la resección quirúrgica convencional. En este artículo, revisamos la técnica de ablación mediante radiofrecuencia. Material y Métodos: Para esta revisión se ha utilizado la base de datos Medline introduciendo los términos “renal radiofrequency ablation”. Resultados: Se analizan los diferentes sistemas que existen en el mercado para la aplicación de radiofrecuencia. Se describen las técnicas de aplicación (abierta, laparoscópica y percutánea), observando una tendencia clara a la aplicación de forma percutánea. En los estudios clínicos publicados existen ya series de pacientes con seguimientos a medio plazo (3 años) en los que se demuestra unos resultados oncológicos semejantes a los de las técnicas de resección clásicas y con un índice de complicaciones menor. Conclusiones: La ablación de tumores renales con radiofrecuencia ha demostrado ser un tratamiento eficaz y con mínimas complicaciones. Sin embargo, hasta que no existan seguimientos a largo plazo, se debe utilizar únicamente en pacientes seleccionados (AU)


Introduction: The standard treatment of small renal masses is partial nephrectomy, which has showed similar oncologic results when compared with radical nephrectomy. Recently, ablative techniques, including radiofrequency and cryotherapy ablation, has been developed, with the purpose of minimizing adverse effects of standard surgical excision. In this article we review the technique of radiofrequency ablation. Material and methods: For this review we conducted a search in the Medline database using the terms “renal radiofrequency ablation”. Results: The different currently marketed systems for the delivery of radiofrequency energy are examined. The different techniques of delivery (open, laparoscopic and percutaneous) are described; we observe a trend towards the use of the percutaneous method. Among the published clinical studies there are series of patients with midterm follow-up (3 years) that show oncologic outcomes similar to traditional resection techniques, with fewer complications. Conclusions: Renal tumor radiofrequency ablation has proved an effective therapy with minimal complications. However, it should be used only in selected patients until longer follow-up studies are available (AU)


Subject(s)
Humans , Male , Female , Kidney Neoplasms/therapy , Kidney Neoplasms , Catheter Ablation/instrumentation , Catheter Ablation/methods , Catheter Ablation/statistics & numerical data , Pulsed Radiofrequency Treatment/instrumentation , Pulsed Radiofrequency Treatment/methods , Pulsed Radiofrequency Treatment , Nephrectomy , Radio Waves/therapeutic use , Laparoscopy/methods , Pneumothorax/pathology , Pneumothorax
10.
Arch Esp Urol ; 60(2): 179-83, 2007 Mar.
Article in Spanish | MEDLINE | ID: mdl-17484485

ABSTRACT

OBJECTIVES: We describe a series of surgical manoeuvres to perform a completely laparoscopic nephroureterectomy. METHODS/RESULTS: We set the patient in the lateral position. The trocars are placed in a rhombus shape, with an accessory trocar for liver retraction on the right side. Once the parietal peritoneum is open the ureter and gonadal vein are localized. We clip and section the gonadal vein. The renal pedicle is localized and dissected. We divide separately the renal artery and vein. We complete the dissection of the kidney. We start the caudal dissection of the ureter from the iliac vessels level down to the pelvis. We clip the ureter. Due to the trocar deployment we reach a point in which ureteral dissection becomes difficult. Then we perform 3 manoeuvres: 1) We change the camera from the lower trocar to the right side one. 2) We move the monitor to the feet of the patient. 3) The surgeon moves to the other side of the patient to work with the superior and inferior trocars. We introduce a retractor through the remaining trocar. With these changes the ureter is in line with the camera and we may have a good access to the pelvis, making the distal dissection of the ureter easier. The dissection ends when the classic image of tent of the vesicoureteral junction is seen. The bladder patch is resected and the bladder is sutured closed with a continuous suture. The specimen is bagged and extracted opening the orifice of the iliac fossa trocar. CONCLUSIONS: With this technique, a completely laparoscopic nephroureterectomy may be performed following the oncological principles of open surgery.


Subject(s)
Laparoscopy/methods , Nephrectomy/methods , Ureter/surgery , Humans , Kidney Neoplasms/surgery , Surgical Instruments , Ureteral Neoplasms/surgery , Urinary Bladder/surgery
11.
Arch. esp. urol. (Ed. impr.) ; 60(2): 179-183, mar. 2007. ilus
Article in Es | IBECS | ID: ibc-055601

ABSTRACT

Objetivo: Describimos en este artículo una serie de maniobras quirúrgicas para realizar la nefroureterectomía totalmente por vía laparoscópica. Métodos/resultados: Colocamos al paciente en posición lateral. Los trócares los situamos haciendo un dibujo en rombo, con un trocar accesorio para separar el hígado en el lado derecho. Una vez realizada la decolación, localizamos el uréter y la vena gonadal. Clipamos y seccionamos la vena gonadal. Localizamos y liberamos el pedículo renal. Seccionamos la arteria y la vena renal por separado. Completamos la liberación del riñón. Iniciamos la liberación del uréter a nivel de los vasos iliacos y vamos descendiendo hacia la pelvis. Clipamos el uréter. Debido a la disposición de los trócares, llega un momento en que la disección ureteral se hace difícil. Es aquí cuando realizamos 3 maniobras: 1) Pasamos la cámara del trocar inferior al trocar derecho. 2) Desplazamos la torre de laparoscopia hacia las piernas del paciente. 3) Después el cirujano se pasa al otro lado de la mesa para poder trabajar con los trócares superior e inferior. Por el trocar sobrante introducimos un separador. De esta manera nos queda el uréter en la misma dirección que la cámara y podemos tener un buen acceso a la pelvis, siendo la disección del uréter distal mas sencilla. La liberación finaliza cuando se observa la clásica imagen en tienda de campaña de la unión ureterovesical. Se reseca un rodete vesical y se cierra la vejiga con una sutura contínua. La pieza se extrae en bloque introducida en una bolsa, ampliando el puerto de la fosa iliaca. Conclusión: Con esta técnica se puede realizar una nefroureterectomía totalmente por vía laparoscópica, siguiendo los principios oncológicos de la cirugía abierta (AU)


Objectives: We describe a series of surgical manoeuvres to perform a completely laparoscopic nephroureterectomy. Methods/Results: We set the patient in the lateral position. The trocars are placed in a rhombus shape, with an accessory trocar for liver retraction on the right side. Once the parietal peritoneum is open the ureter and gonadal vein are localized. We clip and section the gonadal vein. The renal pedicle is localized and dissected. We divide separately the renal artery and vein. We complete the dissection of the kidney. We start the caudal dissection of the ureter from the iliac vessels level down to the pelvis. We clip the ureter. Due to the trocar deployment we reach a point in which ureteral dissection becomes difficult. Then we perform 3 manoeuvres: 1) We change the camera from the lower trocar to the right side one. 2) We move the monitor to the feet of the patient. 3) The surgeon moves to the other side of the patient to work with the superior and inferior trocars. We introduce a retractor through the remaining trocar. With these changes the ureter is in line with the camera and we may have a good access to the pelvis, making the distal dissection of the ureter easier. The dissection ends when the classic image of tent of the vesicoureteral junction is seen. The bladder patch is resected and the bladder is sutured closed with a continuous suture. The specimen is bagged and extracted opening the orifice of the iliac fossa trocar. Conclusions: With this technique, a completely laparoscopic nephroureterectomy may be performed following the oncological principles of open surgery (AU)


Subject(s)
Humans , Laparoscopy/methods , Nephrectomy/methods , Ureter/surgery , Surgical Instruments , Kidney Neoplasms/surgery , Ureteral Neoplasms/surgery , Urinary Bladder/surgery
16.
Arch Esp Urol ; 57(4): 417-24, 2004 May.
Article in Spanish | MEDLINE | ID: mdl-15270284

ABSTRACT

OBJECTIVES: To analyze the complications and morbidity during our learning curve of laparoscopic radical prostatectomy (LRP) and compare them with other published series. METHODS: We review the 25 first laparoscopic radical prostatectomies performed in our department, evaluating the operative technique and other features such as surgical time, blood loss, complications and conversion to open surgery. We also evaluate morbidity, postoperative hospital stay, and functional features such as potency and continence. RESULTS: LRP was completed in 22 patients. Overall intraoperative complication rate was 32%. 3 cases were converted to open surgery due to technical difficulties or intraoperative complications. We had complications in 4 patients, that were not severe (bladder injury 2 cases, and epigastric artery injury another 2) and where solved without difficulties during the operation. The most severe intraoperative complication was related to the anesthesia procedure at the time of extubation of a patient who required tracheotomy. There were no severe postoperative complications, being leakage from the anastomosis the most common (7 cases). All of them were managed conservatively, although this resulted in a mean hospital stay of 10.8 days. 2 patients required endoscopic procedures in the immediate postoperative time for bladder catheter repositioning. All patients suffered erectile dysfunction and the continence rate at 3 months was 77.2%. CONCLUSIONS: Although LRP is a long operation and difficult during the learning curve, its complication rate is acceptable because they are not severe and can be managed in a relatively easy way.


Subject(s)
Intraoperative Complications/epidemiology , Laparoscopy , Prostatectomy/adverse effects , Prostatectomy/education , Aged , Humans , Male , Middle Aged , Postoperative Complications/epidemiology , Prostatectomy/methods
17.
Arch Esp Urol ; 57(3): 303-10, 2004 Apr.
Article in Spanish | MEDLINE | ID: mdl-15174509

ABSTRACT

OBJECTIVES: To evaluate the role of ureteroscopy (rigid and flexible) in the follow-up protocol for transitional cell tumors treated conservatively in our department by endourological procedures, and to review the articles on this topic available in the literature. METHODS: From February 1997 to June 2003, 10 patients (12 renal units) with upper urinary tract urothelial tumor treated conservatively by endourological procedures were followed by cytology, cystoscopy, retrograde ureteropyelography, and ureteroscopy (rigid and flexible), quarterly during the first year, semi-annually during the second year, and yearly thereafter in order to detect tumor recurrence. RESULTS: Mean follow-up was 31.9 months (R 14-65). Two patients died: one because of a previous metacronous bladder tumor and the other after distant progression. One patient was lost to followup. A total of 42 ureteroscopies were performed (31 flexible and 11 rigid). Flexible ureteroscopy was performed in 6 patients and rigid ureteroscopy in three; neither was feasible in one patient so that follow-up was done by cytology, cystoscopy and urography. Tumor recurrence was detected in 2 patients but ureteroscopy did not inform about tumor stage. Flexible ureteroscopy failed in another patient in which rigid ureteroscopy was feasible. Although this latter was technically easier to perform, procedure discomfort was worse. CONCLUSIONS: The follow-up of transitional cell tumors of the upper urinary tract should be very strict because of the high risk of tumor relapse. Ureteroscopy, mainly flexible, is standing out as the most effective procedure to watch these tumors.


Subject(s)
Carcinoma, Transitional Cell/surgery , Kidney Neoplasms/surgery , Ureteral Neoplasms/surgery , Ureteroscopy , Aged , Carcinoma, Transitional Cell/pathology , Female , Follow-Up Studies , Humans , Kidney Neoplasms/pathology , Male , Middle Aged , Neoplasm Staging , Postoperative Complications , Treatment Outcome , Ureteral Neoplasms/pathology , Urinary Tract/pathology , Urinary Tract/surgery
19.
Arch Esp Urol ; 57(10): 1099-106, 2004 Dec.
Article in Spanish | MEDLINE | ID: mdl-15714846

ABSTRACT

OBJECTIVES: To report our experience with laparoscopic pyeloplasty in the treatment of pyeloureteral junction obstruction. METHODS: Between August 2001 and August 2004 14 patients with the diagnosis of pyeloureteral junction obstruction underwent laparoscopic repair. Seven cases had the obstruction on the left side and the other seven on the right side. We describe the technique of laparoscopic dismembered Anderson-Hynes type pyeloplasty, performed to 12 patients in our series. The remainder 2 patients underwent Foley's Y-V plasty and the Fenger's technique. RESULTS: Mean operative time was 199.7 minutes (r: 126-290). There were not intraoperative complications. Mean hospital stay was 4.63 days (r: 3-9). One case of double J catheter obstruction can be cited as late postoperative complication. Only one of the 14 cases suffered a recurrence of the stenosis after double J catheter retrieval. CONCLUSIONS: Laparoscopic pyeloplasty has become the operation of choice in cases of hydronephrosis secondary to crossing vessel, when there is great pyelic dilation, and for the treatment of failures of previous endopyelotomy.


Subject(s)
Kidney Pelvis/surgery , Laparoscopy , Ureteral Obstruction/surgery , Adolescent , Adult , Child , Female , Humans , Male , Middle Aged
20.
Arch Esp Urol ; 55(8): 943-6, 2002 Oct.
Article in Spanish | MEDLINE | ID: mdl-12455285

ABSTRACT

OBJECTIVE: To emphasise a case of splenic hematoma secondary to ESWL. METHODS: We report the case of a 69 year old patient with the diagnosis of left kidney stone who underwent ESWL. The treatment was performed with an electric lithotripter after pre-treatment antibiotic prophylaxis; 2000 shock waves of 18 Kv were given to the patient. RESULTS: Patient presented abdominal pain and hematocrit descent after lithotripsy. The diagnosis of splenic hematoma was established after abdominal ultrasound and CT-scan and the patient was treated conservatively. He required a posterior emergency splenectomy secondary to infection of the hematoma, with the result of death secondary to septic shock. CONCLUSION: Splenic lesion is an exceptional complication after ESWL. There are no studies about the effect of shock waves on the spleen, having been reported only four cases. It is believed that extreme care should be taken in cases with splenic pathology: leukaemia, lymphoma, etc.


Subject(s)
Hematoma/etiology , Kidney Calculi/therapy , Lithotripsy/adverse effects , Spleen/injuries , Abdominal Pain/etiology , Abscess/etiology , Acute Kidney Injury/etiology , Aged , Anti-Bacterial Agents/therapeutic use , Endocarditis, Bacterial/etiology , Enterococcus faecalis , Fatal Outcome , Gram-Positive Bacterial Infections/etiology , Heart Valve Diseases/complications , Hematoma/diagnostic imaging , Hematoma/surgery , Humans , Kidney Calculi/complications , Male , Pleural Effusion/etiology , Premedication , Shock, Septic/etiology , Spleen/diagnostic imaging , Spleen/surgery , Splenectomy , Tomography, X-Ray Computed , Ultrasonography
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