ABSTRACT
No disponible
Subject(s)
Humans , Female , Middle Aged , Erysipelas/chemically induced , Arthritis, Psoriatic/drug therapy , Biological Therapy/adverse effects , Antibodies, Monoclonal/adverse effects , Risk FactorsABSTRACT
En los apicultores se ha descrito una artropatía inflamatoria de etiología desconocida pero relacionada con su actividad profesional. Se expone el caso de un apicultor que tras la picadura de abeja presentó una artritis de la articulación interfalángica del primer dedo de la mano izquierda. Aunque el curso clínico subagudo y los hallazgos de la RMN obligaban a plantear el diagnóstico diferencial con un proceso infeccioso, el resto de pruebas analíticas, de imagen y la evolución, junto al antecedente de episodio similar unos años antes en un dedo de otra mano tras la picadura de abeja, permitió el diagnóstico de esta entidad
An acute inflammatory arthritis of unknown cause has been described in beekeepers in relation to their work with the hives. We present the case of a beekeeper who, after a bee sting, developed arthritis of the interphalangeal joint of the first finger of his left hand. Although the subacute clinical course and the magnetic resonance imaging findings required the differential diagnosis with an infectious process, the rest of the laboratory tests. other imaging studies and the course, together with a history of a similar episode a few years earlier on a finger of the other hand after a bee sting, enabled us to diagnosis this condition
Subject(s)
Humans , Male , Middle Aged , Joint Diseases/diagnostic imaging , Joint Diseases/etiology , Bees , Insect Bites and Stings/complications , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Arthritis/complications , Hand Joints/diagnostic imaging , Hand Joints/pathology , Anti-Bacterial Agents/therapeutic use , Pain Management , Diagnosis, DifferentialABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Hand Dermatoses/etiology , Contracture/complications , Contracture/diagnostic imaging , Finger Phalanges/abnormalities , Finger Joint/pathologyABSTRACT
An acute inflammatory arthritis of unknown cause has been described in beekeepers in relation to their work with the hives. We present the case of a beekeeper who, after a bee sting, developed arthritis of the interphalangeal joint of the first finger of his left hand. Although the subacute clinical course and the magnetic resonance imaging findings required the differential diagnosis with an infectious process, the rest of the laboratory tests. other imaging studies and the course, together with a history of a similar episode a few years earlier on a finger of the other hand after a bee sting, enabled us to diagnosis this condition.
Subject(s)
Arthritis/etiology , Bees , Finger Joint , Insect Bites and Stings/complications , Occupational Diseases/etiology , Animals , Humans , Male , Middle AgedABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Gout/diagnostic imaging , Shoulder JointSubject(s)
Antibodies, Monoclonal, Humanized/administration & dosage , Lung Diseases, Interstitial , Respiratory Distress Syndrome , Still's Disease, Adult-Onset , Administration, Intravenous , Adult , Humans , Immunologic Factors/administration & dosage , Lung/diagnostic imaging , Lung Diseases, Interstitial/diagnosis , Lung Diseases, Interstitial/etiology , Lung Diseases, Interstitial/physiopathology , Male , Radiography, Thoracic/methods , Receptors, Interleukin-6/antagonists & inhibitors , Respiratory Distress Syndrome/etiology , Respiratory Distress Syndrome/physiopathology , Still's Disease, Adult-Onset/complications , Still's Disease, Adult-Onset/therapy , Tomography, X-Ray Computed/methods , Treatment OutcomeABSTRACT
El estudio del incremento de la creatinina fosfoquinasa (CPK) constituye un motivo de consulta frecuente en diversas especialidades médicas. Entre las enfermedades que cursan con CPK alta se encuentran las miopatías metabólicas siendo la enfermedad de McArdle la glucogenosis muscular más frecuente. Presentamos 2 casos clínicos de pacientes derivados a nuestro servicio de reumatología para estudio de CPK elevada cuyo diagnóstico final fue enfermedad de McArdle: un hombre de 72 años, asintomático desde el punto de vista muscular, en el que se objetivó de manera casual elevación importante de CPK en una analítica de rutina y una mujer de 30 años con síntomas musculares muy leves. El electromiograma (EMG) fue normal en ambos pacientes. En ninguno de los 2 casos existía actividad de la miofosforilasa en la biopsia muscular, siendo diagnosticados de enfermedad de McArdle (AU)
A high serum level of creatine kinase (CK) is a common reason for referring to medical specialities. Myopathies are one of the causes of elevated levels of CK. McArdle disease is the most common disorder of skeletal muscle carbohydrate metabolism. The cases are presented on 2 patients who were referred to our medical consultation to study the cause of their increased CK levels: a 72 year old asymptomatic man with high levels of CK detected by chance in a routine analysis, and a 30 year old woman with very few symptoms, apart from slight muscle pain and tiredness. Electromyography was normal in both patients. There was null activity of myophosphorylase in muscle biopsy of both cases, so a diagnosis of McArdle disease was made (AU)
Subject(s)
Humans , Male , Female , Adult , Aged , Glycogen Storage Disease Type V/complications , Glycogen Storage Disease Type V/diagnosis , Glycogen Storage Disease Type V/therapy , Glycogen Phosphorylase, Muscle Form/therapeutic use , Glycogen Storage Disease/complications , Glycogen Storage Disease Type V/diet therapy , Glycogen Storage Disease Type V/physiopathology , Glycogen Storage Disease Type V , Electromyography/methods , AutoimmunityABSTRACT
BACKGROUND/AIMS: Human milk is considered the most suitable food for infants. The potential benefits of breastfeeding can be explained by the presence of different growth and neurotrophic factors in human milk. This study was designed to detect some biomarkers in human milk, which could be involved in the infant neurodevelopment and in the regulation of the maturation of neonatal intestine (brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), glial fibrillary acidic protein (GFAP), fibroblast growth factor 21 (FGF21), lysophosphatidic acid (LPA) and autotaxin (ATX)), and compare them on the basis of the consumption of iodine supplements or multivitamins. METHODS: A prospective study included 37 healthy breastfeeding mothers, divided into 3 different groups: (1) 10 mothers who did not take supplements, (2) 17 mothers who took potassium iodine (KI) 200 µg/day and (3) 10 mothers who took a multivitamin supplement. RESULTS: The concentrations of BDNF, GDNF, GFAP, FGF21, LPA and ATX in human milk were not significantly different in women who took a multivitamin or KI supplement compared with those who did not take any supplement. CONCLUSIONS: The presence of neurotrophic factors in human milk is neither modified by the consumption of supplements nor by their type.
Subject(s)
Iodine/therapeutic use , Milk, Human/chemistry , Pregnancy/metabolism , Adult , Brain-Derived Neurotrophic Factor/analysis , Breast Feeding , Dietary Supplements , Female , Fibroblast Growth Factors/analysis , Glial Cell Line-Derived Neurotrophic Factor/analysis , Glial Fibrillary Acidic Protein/analysis , Humans , Infant, Newborn , Iodine/analysis , Lysophospholipids/analysis , Male , Potassium Iodide , Prospective StudiesABSTRACT
A high serum level of creatine kinase (CK) is a common reason for referring to medical specialities. Myopathies are one of the causes of elevated levels of CK. McArdle disease is the most common disorder of skeletal muscle carbohydrate metabolism. The cases are presented on 2 patients who were referred to our medical consultation to study the cause of their increased CK levels: a 72 year old asymptomatic man with high levels of CK detected by chance in a routine analysis, and a 30 year old woman with very few symptoms, apart from slight muscle pain and tiredness. Electromyography was normal in both patients. There was null activity of myophosphorylase in muscle biopsy of both cases, so a diagnosis of McArdle disease was made.
Subject(s)
Glycogen Storage Disease Type V/diagnosis , Adult , Aged , Female , Humans , MaleABSTRACT
No disponible
Subject(s)
Female , Humans , Middle Aged , Paraneoplastic Syndromes/diagnosis , Vasculitis/diagnosis , Lung Neoplasms/diagnosis , Purpura/etiologySubject(s)
Carcinoma, Squamous Cell/complications , Lung Neoplasms/complications , Neoplasms, Second Primary/complications , Paraneoplastic Syndromes/etiology , Vasculitis, Leukocytoclastic, Cutaneous/etiology , Abdominal Pain/etiology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Breast Neoplasms/therapy , Carcinoma, Ductal, Breast/therapy , Carcinoma, Squamous Cell/drug therapy , Combined Modality Therapy , Female , Humans , Lung Neoplasms/drug therapy , Middle Aged , Neoplasms, Second Primary/drug therapy , Smoking/adverse effectsABSTRACT
No disponible
Subject(s)
Humans , Middle Aged , Mucolipidoses/diagnosis , Mucolipidoses/therapy , Hernia/complications , Pelvic Bones/pathology , Pelvic Bones , Pelvic Neoplasms , Pelvis , Sclerosis/complications , Sclerosis/pathology , Mucolipidoses/pathology , Mucolipidoses , Hammer Toe Syndrome/complications , Hammer Toe Syndrome/pathology , Hammer Toe Syndrome , Lumbar Vertebrae , Pubic SymphysisABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Ehlers-Danlos Syndrome/diagnosis , Cutis Laxa/physiopathology , Joint Instability/physiopathology , Diagnosis, Differential , Risk FactorsABSTRACT
No disponible
