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Ortop Travmatol Protez ; (5): 39-43, 1991 May.
Article in Russian | MEDLINE | ID: mdl-1754200

ABSTRACT

In the process of study of the immunological status peculiarities of 202 patients with some degenerative-dystrophic diseases of hip joint has been revealed that the hyperimmune reactions to tissular antigens of the joint components (bone, cartilage, synovial membrane) are more often observed in case of non-specific arthritis, asephic necrosis of the head of the femur and dysplastic coxarthrosis. These were precisely the states with more frequent postoperative complications, provoking the process development, joint ankylosing or formation of ossificates. Preoperative immunocorrection therapy of 20 patients by means of a course of low-dose injections of plasma substitutes (polyglukine, hemodesis or reopolyglukine), individually selected by RIML and lymphocytotoxic test, allowed to arrest the lryperimmune manifestations. After reconstructive-restorative operations there was observed positive clinical and roentgenologic dynamics in the operated joint of the patients.


Subject(s)
Arthroplasty/methods , Autoantibodies/immunology , Autoantigens/immunology , Femur Head Necrosis/surgery , Knee Joint/surgery , Osteoarthritis, Hip/surgery , Antigen-Antibody Reactions/immunology , Autoantigens/biosynthesis , Cartilage, Articular/immunology , Femur Head Necrosis/immunology , Humans , Knee Joint/immunology , Osteoarthritis, Hip/immunology , Synovial Membrane/immunology
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