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1.
Diagnostics (Basel) ; 13(11)2023 Jun 03.
Article in English | MEDLINE | ID: mdl-37296808

ABSTRACT

Diagnosis of obstructive sleep apnea (OSA) in children with sleep-disordered breathing (SDB) requires hospital-based, overnight level I polysomnography (PSG). Obtaining a level I PSG can be challenging for children and their caregivers due to the costs, barriers to access, and associated discomfort. Less burdensome methods that approximate pediatric PSG data are needed. The goal of this review is to evaluate and discuss alternatives for evaluating pediatric SDB. To date, wearable devices, single-channel recordings, and home-based PSG have not been validated as suitable replacements for PSG. However, they may play a role in risk stratification or as screening tools for pediatric OSA. Further studies are needed to determine if the combined use of these metrics could predict OSA.

2.
Cureus ; 14(12): e32468, 2022 Dec.
Article in English | MEDLINE | ID: mdl-36644038

ABSTRACT

In this study, we present the case of a 10-year-old boy with a left-sided neck mass. Although most neck masses in children are non-cancerous, their etiology can be complex, especially in neck masses of congenital origin. The workup of a pediatric neck mass includes imaging and cytopathology. In this case, the histopathology of the excised mass revealed thymic tissue, which helped establish the diagnosis of a thymopharyngeal duct cyst. Thymophayngeal duct cysts, although rare, can be diagnosed preoperatively by characteristic tapering toward the mediastinum. Cytopathology may demonstrate Hassall corpuscles. These unique features can help disentangle the differential diagnoses, which commonly include thyroglossal duct cysts, venolymphatic malformations, and branchial cleft cysts.

3.
Am J Trop Med Hyg ; 91(6): 1154-5, 2014 12.
Article in English | MEDLINE | ID: mdl-25331804

ABSTRACT

Rocky Mountain spotted fever, a tick-borne disease caused by Rickettsia rickettsii, is challenging to diagnose and rapidly fatal if not treated. We describe a decedent who was co-infected with group A ß-hemolytic streptococcus and R. rickettsii. Fatal cases of Rocky Mountain spotted fever may be underreported because they present as difficult to diagnose co-infections.


Subject(s)
Rocky Mountain Spotted Fever/diagnosis , Streptococcal Infections/complications , Streptococcus pyogenes/isolation & purification , Adult , Humans , Male , Polymerase Chain Reaction , Rocky Mountain Spotted Fever/complications
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