ABSTRACT
Moyamoya syndrome is a rare chronic progressive disease of brain vessels in which certain arteries in the brain are constricted. During the disease a collateral circulation develops around the blocked vessels to compensate for the blockage, and on angiography these collateral vessels have the appearance of a "puff of smoke". Moyamoya syndrome is extremely rare disease, especially outside of Japan We describe a clinical case of a 27-year-old patient from Tomsk with Moyamoya disease. The clinical features are an acute stroke in the right middle cerebral artery with dysarthria and paralysis of VII and XII cranial nerves. The diagnosis of moyamoya is suggested by MRI-angiogram results in accordance to the diagnostic criteria.
Subject(s)
Brain Ischemia/diagnosis , Moyamoya Disease/diagnosis , Adult , Brain/pathology , Brain Ischemia/complications , Dysarthria/diagnosis , Dysarthria/etiology , Facial Nerve Diseases/diagnosis , Facial Nerve Diseases/etiology , Humans , Hypoglossal Nerve Diseases/diagnosis , Hypoglossal Nerve Diseases/etiology , Magnetic Resonance Angiography , Male , Middle Cerebral Artery/pathology , Moyamoya Disease/complications , Moyamoya Disease/surgery , Treatment OutcomeABSTRACT
Choline-positive neuroprotectors citicoline and choline alfoscerate decreased blood concentration of protein S100 in clinical trial on 52 patients in the first days after acute ischemic stroke. Neuroprotective therapy has also produced stabilization of blood-brain barrier.
