ABSTRACT
The examination of 404 patients with periodic disease (301 with uncomplicated form and 104 with amyloidosis complication) has detected decreased functional activity of T-lymphocytes and their suppressor subpopulation, their subnormal quantity. There was a rise in T-helper/T-suppressor index, level of B- and 0-lymphocytes, sensitivity to the renal antigen. Colchicin therapy stopped the attacks and stimulated T-suppressor activity. Combined treatment with tactivin is proposed.
Subject(s)
B-Lymphocytes/immunology , Familial Mediterranean Fever/immunology , Familial Mediterranean Fever/physiopathology , T-Lymphocytes/immunology , Adolescent , Adult , Female , Humans , Male , Middle AgedSubject(s)
Colchicine/administration & dosage , Familial Mediterranean Fever/drug therapy , Adolescent , Adult , Demecolcine/therapeutic use , Drug Evaluation , Familial Mediterranean Fever/diet therapy , Familial Mediterranean Fever/immunology , Female , Humans , Immunity/drug effects , Male , Middle Aged , Time FactorsSubject(s)
Cell Migration Inhibition , Giardiasis/immunology , Lymphocytes/immunology , Adolescent , Adult , Child , Child, Preschool , Humans , Immunity, Cellular , Middle Aged , Time FactorsABSTRACT
Adult white rats were immunized by numerous subcutaneous injections of antigenes obtained from the cultures of B. coli and B. suis. After the rats were sensibilized they were infected with cultural forms of Balantidium. 75% of infected rats were found to have ciliates in the lumen of the large intestine. In the tissues of the intestinal wall up to the muscular layer there were observed certain pathomorphological changes such as hyperemy, oedema, haemorrhagia and ulcers. By means of the macrophaga migration test it was established that in rats during their immunization and following infection appear lymphocytes which are sensibilized in relation to the balantidial antigene that points to the formation of slow allergy in their organisms.
