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1.
Vestn Otorinolaringol ; (2): 17-22, 2008.
Article in Russian | MEDLINE | ID: mdl-18454071

ABSTRACT

A prospective non-randomized trial was made to evaluate incidence of gastroesophageal reflux disease (GERD) and pharyngolaryngeal reflux (PLR) in children with chronic laryngeal pathology. A total of 46 children aged 6 to 15 years were examined including 16 patients with recurrent respiratory papillomatosis, 15 patients with acquired laryngotracheal scarry stenosis and 15 patients with vocal nodules and functional dysphonia. Combination of GERD with PLR is a factor of risk for scarry laryngostenosis in a child with recurrent respiratory papillomatosis. If it is impossible to perform 24-h pH-monitoring of the esophagus for detection of GERD or PLR in patients with chronic laryngeal pathology, antireflux therapy is prescribed empirically. It is necessary to establish significant diagnostic criteria of PLR.


Subject(s)
Gastroesophageal Reflux/epidemiology , Gastroesophageal Reflux/physiopathology , Laryngeal Neoplasms/epidemiology , Laryngostenosis/epidemiology , Papilloma/epidemiology , Pharynx/physiopathology , Adolescent , Child , Female , Humans , Hydrogen-Ion Concentration , Male , Mass Screening , Prospective Studies , Vocal Cords/pathology
2.
Eksp Klin Gastroenterol ; (7): 104-10, 2008.
Article in Russian | MEDLINE | ID: mdl-19334453

ABSTRACT

UNLABELLED: Data about patogenesis, clinical characteristics, diagnostics, treatment and the forecast of diseases of the upper departments of respiratory ways at children in a combination with gastroesophageal reflux disease (GRD) are presented proceed on the literature and own experience data. The purpose of ours research consisted in revealing of correlation dependence between GRD and chronic diseases of a throat at children. 77 children at the age of 5-16 years with the nonheritable cicatricial stenosis of a throat and cervical department of a trachea (n = 12), with small knots of vocal folds (n = 17), with dysphonia (n = 20) and with anticipate respiratory papillomatosis (n = 28) are surveyed. Reflux disease is diagnosed by means of the developed technique of pH-monitoring at which electrodes were established in hypopharynx, average and bottom departments of a gullet. RESULTS: at definitive rare frequency of clinical GRD signs at children with various variants of reflux disease in 74 cases (96,1%): GRD in a combination with pharyngolaryngeal a reflux (FR)---at 48 children (62,3 %), isolated FR---at 18 children (23,4 %), isolated GRD--in 8 cases (10,4 %). CONCLUSIONS: 1) correlation between chronic diseases of a throat at children and GRD is established; 2) in case of isolated FR often works protective alkalize gullet mechanism; 3) with chronic diseases of a throat it is expedient to include carrying out of daily pH-monitoring in the plan of inspection of children; 4) prospective FR participation in pathogenesis of chronic throat diseases demands carrying out of the further researches.


Subject(s)
Gastroesophageal Reflux/complications , Gastroesophageal Reflux/diagnosis , Respiratory Tract Diseases/complications , Respiratory Tract Diseases/diagnosis , Adolescent , Child , Child, Preschool , Endoscopy, Digestive System , Gastroesophageal Reflux/epidemiology , Humans , Respiratory Tract Diseases/epidemiology
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