ABSTRACT
A variety of changes in placental villi are known to occur in Pregnancy Induced Hypertension. In this study an attempt is made to study 49 placentae from PIH and its correlation to perinatal outcome. Quantification of villous lesions was carried out. The striking villious changes were cytotrophoblastic proliferation, paucity of vasculosyncytial membrane, trophoblastic basement membrane thickening and fibrinoid necrosis of villi. The changes were directly proportional to the severity of disease and perinatal outcome was worse with advancing grades of PIH.
Subject(s)
Hypertension, Pregnancy-Induced/pathology , Hypertension, Pregnancy-Induced/physiopathology , Placenta/pathology , Apgar Score , Chorionic Villi/pathology , Eclampsia/pathology , Female , Fetal Death , Humans , Infant, Low Birth Weight , Infant, Newborn , Pregnancy , Pregnancy Outcome , Severity of Illness Index , Trophoblasts/pathologyABSTRACT
Kasabach-Meritt syndrome is a combination of thromobocytopenia, hemolytic anemia, and acute or chronic consumptive coagulopathy in association with rapidly enlarging hemangioma. A male infant of 5 days was admitted in paediatric ward with this syndrome. The baby had ecchymotic patches over face and extremities and bleeding through umbilical stump. The child expired due to severe thrombocytopenia with consumptive coagulopathy leading to precipituous hemorrhage superimposed by septicemia. An autopsy was performed which confirmed retroperitoneal lesion as kaposiform hemangioendothelioma.
Subject(s)
Anemia, Hemolytic/pathology , Disseminated Intravascular Coagulation/pathology , Hemangioendothelioma/pathology , Retroperitoneal Neoplasms/pathology , Thrombocytopenia/pathology , Fatal Outcome , Humans , Infant, Newborn , Male , SyndromeABSTRACT
Gonadoblastoma is an uncommon tumour of ovary occurring exclusively in patients with inter sex disorders. We are presenting an unusual case of gonadoblastoma with distinctly rare pattern of germ cell overgrowth on the other side in an eighteen year old girl.
Subject(s)
Gonadoblastoma/pathology , Neoplasms, Germ Cell and Embryonal/pathology , Ovarian Neoplasms/pathology , Adolescent , Female , Germ Cells/pathology , Humans , Neoplasms, Multiple Primary/pathologyABSTRACT
Bilateral total renal dysplasia is an extremely rare congenital anomaly associated with Potter's facies. We report an autopsy case of a stillborn male child. Histopathology is showing persistence of structures not seen in normal development.
Subject(s)
Kidney/abnormalities , Adult , Facies , Female , Fetal Death/etiology , Fetal Death/pathology , Humans , Male , Oligohydramnios , Pregnancy , Pregnancy OutcomeABSTRACT
A study of 100 neonates with clinical suspicion of septicemia, admitted in neonatal intensive care unit of SCSM General Hospital, Solapur was carried out to assess the utility of various indices of sepsis screen. Bacterial and hematological profile of these neonataes was studied. Parameters of sepsis screen such as leukocyte count, band form to neutrophil ratio, neutrophils with toxic granulations, micro ESR and test for C-reactive protein were analysed to know their sensitivity and specificity.
Subject(s)
Sepsis/diagnosis , Blood Sedimentation , C-Reactive Protein/metabolism , Humans , India , Infant, Newborn , Intensive Care, Neonatal , Leukocyte Count , Neutrophils/pathology , Sepsis/blood , Sepsis/microbiologyABSTRACT
A study of 200 cases of primary and secondary infertility was carried out in the department of pathology, Dr. V.M. Medical College, Solapur. Endometrial specimens were evaluated in the light of menstrual history to find out the incidence of various endometrial changes in cases of infertility. All cases underwent endometrial biopsy premenstrually. Haematoxylin and eosin staining was done for dating of endometrium and diagnosis of corpus luteal defect and anovalutory cycles. PAS stain was done in 50 cases of infertility with control of 25 cases to detect the amount of glycogen. Menstrual problems were seen in 38.2% of patients. Anovulatory infertility was present in 28.2% cases. Luteal phase defect was seen in 20% cases. Cystoglandular hyperplasia was seen in 1.7% cases & tuberculous endometritis was present in 2.6% cases. Glycogen deficiency was seen in 30% cases of luteal phase defect.
Subject(s)
Endometrium/pathology , Infertility, Female/pathology , Adolescent , Adult , Case-Control Studies , Endometrium/metabolism , Female , Glycogen/metabolism , Humans , Infertility, Female/metabolism , Luteal PhaseABSTRACT
Thirty patients of lepromatous leprosy in a state of reaction (ENL) were studied for bacillaemia and a correlation was made with liver pathology. Buffy coat smears were examined in all, eliminating as far as possible the chances of contamination of blood by the skin bacilli. Thirteen out of thirty patients showed presence of acid fast bacilli (AFB) in the buffy coat smear. Hepatic involvement in the form of leprous granuloma was observed in all, of which 93.3% showed presence of AFB. It is concluded that during reaction the possibility of heightened bacillaemia is less likely and that the systemic spread of infection is not accentuated during the bouts of reaction.
