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1.
Ginecol Obstet Mex ; 71: 118-23, 2003 Mar.
Article in Spanish | MEDLINE | ID: mdl-12793019

ABSTRACT

OBJECTIVE: To evaluate the bone mass condition in the different types of menopause and know if there is difference between the groups. DESIGN: Case reports. MATERIAL AND METHODS: From September through November 2001 at the Specialties Hospital No. 1, we studied 184 patients with menopause. They were divided in 5 groups: 74 regular menopause, 31 surgical menopause and oophorectomy unilateral, 43 surgical menopause and bilateral oophorectomy, 32 premature menopause, and 4 post-radiotherapy menopause, analyzing the bone mass with a densitometry. The statistical analysis was by descriptive statistics and t student to find the difference between the groups. RESULTS: We observed 45% with osteopenia y 8% with osteoporosis in regular menopause. In surgical menopause and oophorectomy unilateral group, we found 26% with osteopenia and 6% with osteoporosis. There were 42% with ostepenia and 14% with osteopososis in surgical menopause and bilateral oophorectomy group. In premature menopause, we found 47% with osteopenia and 12% with osteoporosis. In post-radiotherapy menopause, we found 75% with osteopenia and 25% with osteoporosis. All of them with predominance in femur. We did not observe any significant difference between the surgical and the premature menopause groups. CONCLUSIONS: In a half of patients with menopause we found bone mass decrease with predominance in femur, like osteopenia. There was no significant difference between the surgical and the premature menopause groups.


Subject(s)
Bone Density , Menopause/physiology , Osteoporosis, Postmenopausal/physiopathology , Absorptiometry, Photon , Adult , Aged , Bone Diseases, Metabolic/physiopathology , Female , Femur Head/diagnostic imaging , Femur Head/pathology , Gynecologic Surgical Procedures/adverse effects , Humans , Lumbar Vertebrae/diagnostic imaging , Lumbar Vertebrae/pathology , Middle Aged
2.
Ginecol. obstet. Méx ; 68(12): 469-75, dic. 2000. graf
Article in Spanish | LILACS | ID: lil-286230

ABSTRACT

Introducción. La premenopausia se refiere a la parte del climaterio que precede a la menopausia, donde se presenta una disminución de las hormonas ováricas, que conduce a enfermedades cardiovasculares como hipertensión arterial, infarto agudo del miocardio y accidente cerebrovascular. Objetivo. Evaluar la respuesta antihipertensiva del estradiolmedroxiprogesterona, para reducir la presión arterial en la paciente premenopáusica. Material y métodos. En un ensayo clínico del primero de marzo de 1997 al 30 septiembre de 1998, se evaluaron 106 pacientes con hipertensión arterial, hipoestrogenismo clínico y estradiol inferior a 30 pg/mL, se asignaron al azar a dos grupos con seguimiento de seis meses. Grupo A: 53 con captopril, Grupo B: 53 con estradiolmedroxiprogesterona, antes y después del tratamiento se analizaron la presión arterial, colesterol, triglicéridos e hipoestrogenismo clínico. (El análisis estadístico fue con prueba para diferencias de medias). Resultados. Se observó una disminución de la presión arterial con estradiol igual que con captopril, con una p < 0.05. La disminución del colesterol y triglicéridos fue más significativa en el grupo estradiol con una p < 0.05. Existió una mayor atenuación de la sintomatología del hipoestrogenismo en el grupo con estradiol. Conclusiones. La respuesta antihipertensiva con estradiol fue igual que con captopril en las pacientes hipertensivas premenopáusicas.


Subject(s)
Humans , Female , Adult , Middle Aged , Captopril/therapeutic use , Estradiol/therapeutic use , Hypertension/drug therapy , Medroxyprogesterone/therapeutic use , Premenopause/drug effects , Antihypertensive Agents/therapeutic use , Blood Pressure
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