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1.
Pan Afr Med J ; 39: 95, 2021.
Article in French | MEDLINE | ID: mdl-34466197

ABSTRACT

Limbic encephalitis (LE) is a rare disease often of paraneoplastic origin. It is frequently associated with bronchopulmonary cancer. Diagnosis is based on brain magnetic resonance imaging (MRI). We here report the case of a 54-year-old female patient with a history of active smoking, presenting with chronic dry cough. Chest X-ray showed suspicious right lung opacity. Bronchial fibroscopy and bronchial biopsies were not contributory. Thoraco-abdomino-pelvic computed tomography (CT)-scan and brain CT-scan showed a mass in the right upper lobe classified as T4N2M1a. CT-guided lung biopsy confirmed the diagnosis of bronchopulmonary adenocarcinoma. The patient had reported a recent history of memory disturbances associated with depressed mood, anxiety and paroxysmal confusion. Metabolic screening and tests for detecting infection were normal and brain MRI suggested limbic encephalitis. The evolution was characterized by rapid disease progression; the patient died in about ten days.


Subject(s)
Adenocarcinoma of Lung/diagnostic imaging , Limbic Encephalitis/diagnostic imaging , Lung Neoplasms/diagnostic imaging , Adenocarcinoma of Lung/complications , Disease Progression , Fatal Outcome , Female , Humans , Limbic Encephalitis/etiology , Lung Neoplasms/complications , Magnetic Resonance Imaging , Middle Aged , Tomography, X-Ray Computed
2.
Pan Afr Med J ; 37: 201, 2020.
Article in French | MEDLINE | ID: mdl-33505570

ABSTRACT

Bronchopulmonary cancer is the leading cause of death in men and the second in women. Some endoscopic or radiological features may guide histological diagnosis and thus facilitate therapeutic management. We here report the case of a 54-year old man, with a history of smoking and recent coronary stent implantation, presenting with haemoptysis and worsening of dyspnea which had evolved over the last month. Chest x-ray showed left pulmonary hemifield lucency with signs of retraction. Bronchial fibroscopy objectified raspberry bud formation spontaneously bleeding, originating from the left main bronchus and suggesting carcinoid tumor. Chest computed tomography (CT) scan showed poorly enhanced endoluminal tissue process at the level of the left main bronchus, located four cm from the carina and complicated with atelectasis. Diagnostic and therapeutic surgery helped to adjust to a diagnosis of endobronchial amartocondroma.


Subject(s)
Bronchial Neoplasms/diagnosis , Hamartoma/diagnosis , Pulmonary Atelectasis/diagnosis , Bronchial Neoplasms/pathology , Bronchial Neoplasms/surgery , Bronchoscopy , Carcinoid Tumor/diagnosis , Dyspnea/etiology , Fiber Optic Technology , Hamartoma/pathology , Hamartoma/surgery , Hemoptysis/etiology , Humans , Male , Middle Aged , Tomography, X-Ray Computed
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