Seeing Clearly: Effects of Initiatives to Improve Diabetic Retinopathy Screening at a Pediatric Center.

IN BRIEF "Quality Improvement Success Stories" are published by the American Diabetes Association in collaboration with the American College of Physicians, Inc. (ACP), and the National Diabetes Education Program. This series is intended to highlight best practices and strategies from programs and clinics that have successfully improved the quality of care for people with diabetes or related conditions. Each article in the series is reviewed and follows a standard format developed by the editors of Clinical Diabetes. The following article describes an initiative to improve retinopathy screening rates at the pediatric diabetes clinic of a large academic teaching hospital in Canada.

Limited Utility of Biochemical Screening for Pituitary Deficiencies and Adverse Effects in Idiopathic GH Deficiency.

CONTEXT: In children with isolated growth hormone (GH) deficiency (GHD), routine biochemical screening for multiple pituitary hormone deficiencies (MPHD) and adverse effects related to growth hormone (GH) treatment are frequently performed. More evidence is needed to support this practice. OBJECTIVES: To evaluate the rate of development of MPHD among children initially diagnosed with isolated GHD and to assess the utility of screening tests to identify complications of GH therapy. DESIGN: Retrospective analysis of subjects treated with GH since 2005. For the first objective, only subjects diagnosed with GHD were included. Subjects were excluded if GHD was associated with an acquired disorder or condition known to be associated with pituitary abnormalities. For the second objective, other GH-treated diagnoses were included. PATIENTS: A total of 328 subjects (171 with GHD, 154 with idiopathic short stature, and three with SHOX deficiency). RESULTS: In subjects with isolated GHD, MPHD was diagnosed in seven (4.2%) after a mean of 35.4 months (range, 9.4 to 68.0). Sex, age at diagnosis, duration of GH, and peak stimulated GH levels were not associated with developing MPHD. Among subjects with an MRI abnormality, 13.9% developed MPHD (OR, 6.3; 95% CI, 1.2 to 33.7). In the entire cohort, three subjects (0.9%) developed dysglycemia, and no subject had persistently abnormal liver or renal function tests. CONCLUSIONS: There is a limited role for routine biochemical screening for MPHD in children with idiopathic isolated GHD or for adverse effects in otherwise healthy children. Routine biochemical screening for MPHD should be limited to those with an abnormal MRI.

Paediatric type 1 diabetes 2018: Clinical and research insights.

The management of children and adolescents with type 1 diabetes continues to progress as clinical and technological innovations enter into practice. Variability in glucose readings can present a significant challenge for care providers, patients and families alike and recent research demonstrates that insulin selection and site-related lipohypertrophy can significantly influence blood glucose levels. New technology aims to improve both glycemic control and quality of life. New insulin analogues have been developed and insulin pumps and continuous glucose monitoring systems continue to evolve toward a fully closed-loop system. While such systems are not yet currently available, incremental features such as 'low glucose suspend' are offered. As well, glucose sensors are now available that can be used for insulin dosing while reducing the number of capillary blood sugar checks. This review aims to provide the clinician with an overview of some of these latest aspects of diabetes care for children and adolescents.

Evaluation of delayed puberty: what diagnostic tests should be performed in the seemingly otherwise well adolescent?

Delayed puberty (DP) is defined as the lack of pubertal development by an age that is 2-2.5 SDs beyond the population mean. Although it generally represents a normal variant in pubertal timing, concern that DP could be the initial presentation of a serious underlying disorder has led to a diagnostic approach that is variable and may include tests that are unnecessary and costly. In this review, we examine available literature regarding the recommended diagnostic tests and aetiologies identified during the evaluation of youth with DP. We view this literature through the prism of the seemingly otherwise well adolescent. To provide further clinical context, we also evaluate the clinical and laboratory data from patients seen with DP in our centre over a 2-year period. The literature and our data reveal wide variability in the number of tests performed and raise the question of whether tests, other than gonadotropins, obtained in the absence of signs or symptoms of an underlying disorder are routinely warranted. Together this information provides a pragmatic rationale for revisiting recommendations calling for broad testing during the initial diagnostic evaluation of an otherwise healthy adolescent with DP. We highlight the need for further research comparing the utility of broader screening with a more streamlined approach, such as limiting initial testing to gonadotropins and a bone age, which, while not diagnostic, is often useful for height prediction, followed by close clinical monitoring. If future research supports a more streamlined approach to DP, then much unnecessary testing could be eliminated.

Strategies to improve recruitment into rheumatology: results of the Workforce in Rheumatology Issues Study (WRIST).

OBJECTIVE: By 2026, there will be a 64% shortfall of rheumatologists in Canada. A doubling of current rheumatology trainees is likely needed to match future needs; however, there are currently no evidence-based recommendations for how this can be achieved. The Workforce in Rheumatology Issues Study (WRIST) was designed to determine factors influencing the choice of rheumatology as a career. METHODS: An online survey was created and invitations to participate were sent to University of Western Ontario (UWO) medical students, UWO internal medicine (IM) residents, Canadian rheumatology fellows, and Canadian rheumatologists. Surveys sent to each group of respondents were identical except for questions related to demographics and past training. Participants rated factors that influenced their choice of residency and scored factors related to the attractiveness of rheumatology and to recruitment strategies. Statistical significance was determined using chi-squared and factor analysis. RESULTS: The survey went out to 1014 individuals, and 491 surveys were completed (48.4%). Responses indicated the importance of exposure through rotations and role models in considering rheumatology. Significant (p < 0.002) differences between groups were evident regarding what makes rheumatology attractive and effective recruitment strategies, most interestingly with rheumatologists and trainees expressing opposite views on the latter. CONCLUSION: Recommendations are made in 2 broad categories: greater exposure and greater information. As medical students and IM residents progress through their training, their interest in rheumatology lessens, thus it is important to begin recruitment initiatives as early as possible in the training process.