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Bull Environ Contam Toxicol ; 96(6): 822-6, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27107585

ABSTRACT

Fungicide azoxystrobin toxicity was monitored by means of a 96-h biotest with Artemia franciscana nauplius stages after exposure to solutions with concentrations of 0.2, 0.4, 0.6 and 0.8 mg L(-1) irradiated with (60)Co gamma radiation with doses of 1, 2.5, 5 and 10 kGy. The effects of ionization radiation on azoxystrobin toxicity were mainly manifested by a statistically significant reduction of lethality after 72- and 96-h exposure. A maximum reduction of lethality of 72 % was achieved using doses of 1-5 kGy for an azoxystrobin initial concentration of 0.4 mg L(-1) and after 72 h of exposure. At a 96-h exposure, a difference of lethal effects reached up to 70 % for a dose of 10 kGy. The observed effect of gamma ionizing radiation on azoxystrobin toxicity suggest that this approach can be applied as an alternative for a reduction of azoxystrobin residua in food.


Subject(s)
Antifungal Agents/toxicity , Artemia/drug effects , Artemia/radiation effects , Gamma Rays , Methacrylates/toxicity , Pyrimidines/toxicity , Animals , Antifungal Agents/chemistry , Dose-Response Relationship, Drug , Dose-Response Relationship, Radiation , Food Analysis , Food Contamination/analysis , Food Microbiology , Lethal Dose 50 , Methacrylates/chemistry , Pyrimidines/chemistry , Radiation, Ionizing , Strobilurins
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