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Ann Hepatol ; 6(4): 272-5, 2007.
Article in English | MEDLINE | ID: mdl-18007560

ABSTRACT

Hepatic artery thrombosis (HAT) is the most common vascular complication of orthotopic liver transplantation (OLT) and constitutes a potential emergency during the postoperative period. Surgical revascularization and retransplantation are the treatments of choice for this condition. The aim of this report is to present long-term follow-up on survival and graft function of three patients with paclitaxel-coated hepatic artery stents placed percutaneously after earlyonset HAT. Three patients developed early onset HAT after cadaveric-donor OLT in a tertiary care center in Mexico. These patients were treated percutaneously with balloon angioplasty and paclitaxel-coated stents. After 24 months or more of follow-up, 2 patients present total occlusion of the stent and one patient, intra-stent stenosis; interestingly, all patients have normal graft function and excellent quality of life. In conclusion, although balloon angioplasty and stent placement may be a therapeutic option for suitable patients with early-onset HAT after OLT, longterm patency is unlikely even with the use of paclitaxel- coated materials.


Subject(s)
Drug-Eluting Stents , Hepatic Artery , Liver Transplantation/adverse effects , Paclitaxel/administration & dosage , Postoperative Complications/therapy , Thrombosis/therapy , Tubulin Modulators/pharmacology , Adult , Angioplasty, Balloon , Aspirin/pharmacology , Clopidogrel , Female , Humans , Male , Mexico , Middle Aged , Platelet Aggregation Inhibitors/pharmacology , Postoperative Complications/etiology , Thrombosis/etiology , Ticlopidine/analogs & derivatives , Ticlopidine/pharmacology , Vascular Surgical Procedures
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