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1.
Nutrients ; 13(7)2021 Jul 15.
Article in English | MEDLINE | ID: mdl-34371943

ABSTRACT

AIM: Hospital food provision is subject to multiple constraints (meal production, organization, health safety, environmental respect) which influence the meal tray offered to the patient. Multiple diets can add complexity and contribute to non-consumption of the meal. To avoid undernutrition, it appeared necessary to propose guidelines for foods and diets in hospitals. METHODS: These guidelines were developed using the Delphi method, as recommended by the HAS (French Health Authority), based on a formal consensus of experts and led by a group of practitioners and dieticians from the AFDN (French Association of Nutritionist Dieticians) and SFNCM (French Society of Clinical Nutrition and Metabolism). RESULTS: Twenty-three recommendations were deemed appropriate and validated by a panel of 50 national experts, following three rounds of consultations, modifications and final strong agreement. These recommendations aim to define in adults: 1-harmonized vocabulary related to food and diets in hospitals; 2-quantitative and qualitative food propositions; 3-nutritional prescriptions; 4-diet patterns and patient adaptations; 5-streamlining of restrictions to reduce unnecessary diets and without scientific evidence; 6-emphasizing the place of an enriched and adapted diet for at-risk and malnourished patients. CONCLUSION: These guidelines will enable catering services and health-care teams to rationalize hospital food and therapeutic food prescriptions in order to focus on individual needs and tasty foods. All efforts should be made to create meals that follow these recommendations while promoting the taste quality of the dishes and their presentation such that the patient rediscovers the pleasure of eating in the hospital.


Subject(s)
Diet, Healthy/standards , Food Service, Hospital/standards , Nutrition Policy , Nutrition Therapy/standards , Consensus , Delphi Technique , Feeding Behavior , France , Humans , Inpatients , Meals , Nutritional Status , Nutritive Value , Policy Making , Recommended Dietary Allowances
2.
JPEN J Parenter Enteral Nutr ; 42(1): 255-260, 2018 01.
Article in English | MEDLINE | ID: mdl-29505137

ABSTRACT

BACKGROUND: Malnutrition is a critical predictor of toxicity and outcome in patients with cancer and may be perceived differently by patients, relatives, and physicians. AIMS: To assess the prevalence of malnutrition in oncology departments and to compare it with the perceptions of nutrition status by patients themselves, their closest relatives, and attending physicians. MATERIALS AND METHODS: A 1-day multicentric cross-sectional survey on the prevalence of malnutrition was conducted in different oncology departments using patient-, relative-, and physician-specific questionnaires. Malnutrition was defined by a weight loss ≥5% within 1 month or ≥10% within 6 months, a body mass index ≤18.5 kg/m2 in patients aged <70 years or ≤21 kg/m2 in patients aged ≥70 years, and/or albuminemia <35 g/L. Questionnaires for assessing medical condition, knowledge of nutrition status, and perceptions of the impact of malnutrition on daily life were distributed to consenting patients, attending physicians, and closest relatives. RESULTS: A total of 2197 patients were included, and 2071 and 976 questionnaires were collected from patients and relatives, respectively. Prevalence of malnutrition was 39%. Physicians overestimated malnutrition (44%), whereas patients and relatives underestimated it (22% and 23%, respectively, P < .001). Conversely, malnutrition-associated symptoms were underestimated by physicians compared with patients and relatives. CONCLUSION: We found a prevalence of malnutrition of 39%: it was underestimated by patients and relatives and overestimated by physicians.


Subject(s)
Attitude to Health , Malnutrition/diagnosis , Malnutrition/epidemiology , Neoplasms/epidemiology , Nutritional Status , Adolescent , Adult , Aged , Aged, 80 and over , Comorbidity , Cross-Sectional Studies , Family , Female , Humans , Middle Aged , Physicians , Prevalence , Surveys and Questionnaires , Young Adult
3.
Age (Dordr) ; 34(2): 371-87, 2012 Apr.
Article in English | MEDLINE | ID: mdl-21472380

ABSTRACT

Leucine acts as a signal nutrient in promoting protein synthesis in skeletal muscle and adipose tissue via mTOR pathway activation, and may be of interest in age-related sarcopenia. However, hyper-activation of mTOR/S6K1 has been suggested to inhibit the first steps of insulin signaling and finally promote insulin resistance. The impact of long-term dietary leucine supplementation on insulin signaling and sensitivity was investigated in old rats (18 months old) fed a 15% protein diet supplemented (LEU group) or not (C group) with 4.5% leucine for 6 months. The resulting effects on muscle and fat were examined. mTOR/S6K1 signaling pathway was not significantly altered in muscle from old rats subjected to long-term dietary leucine excess, whereas it was increased in adipose tissue. Overall glucose tolerance was not changed but insulin-stimulated glucose transport was improved in muscles from leucine-supplemented rats related to improvement in Akt expression and phosphorylation in response to food intake. No change in skeletal muscle mass was observed, whereas perirenal adipose tissue mass accumulated (+45%) in leucine-supplemented rats. A prolonged leucine supplementation in old rats differently modulates mTOR/S6K pathways in muscle and adipose tissue. It does not increase muscle mass but seems to promote hypertrophy and hyperplasia of adipose tissue that did not result in insulin resistance.


Subject(s)
Adipose Tissue/metabolism , Aging/physiology , Dietary Supplements , Insulin Resistance/physiology , Insulin/metabolism , Leucine/administration & dosage , Muscle, Skeletal/metabolism , Adipose Tissue/drug effects , Aging/drug effects , Animals , Biological Transport/genetics , Blotting, Western , Disease Models, Animal , Follow-Up Studies , Glucose/metabolism , Glucose Tolerance Test , Male , Muscle, Skeletal/drug effects , RNA/genetics , Rats , Rats, Wistar , Real-Time Polymerase Chain Reaction , Ribosomal Protein S6 Kinases/biosynthesis , Ribosomal Protein S6 Kinases/drug effects , Ribosomal Protein S6 Kinases/genetics , Sarcopenia/diet therapy , Sarcopenia/genetics , Sarcopenia/metabolism , Signal Transduction/drug effects , TOR Serine-Threonine Kinases/biosynthesis , TOR Serine-Threonine Kinases/drug effects , TOR Serine-Threonine Kinases/genetics , Time Factors
4.
Clin Nutr ; 31(1): 69-73, 2012 Feb.
Article in English | MEDLINE | ID: mdl-21872973

ABSTRACT

BACKGROUND & AIMS: Elderly subjects are at risk for undernutrition. Restrictive diets may increase this risk. The aim was to evaluate the impact of restrictive diets on undernutrition and its risk in free-living elderly. METHODS: Ambulatory patients over age 75 and under a restrictive diet (low salt, low cholesterol, diabetic) were included prospectively, along with age- and gender-matched controls. Weight and height were measured, and the short-form of the Mini Nutritional Assessment was scored. Groups were compared to determine variables associated with a low MNA-SF(®). RESULTS: 95 patients in the diet group (62 F, 33 M, 80 ± 4 y) and 95 controls (57 F, 38 M, 82 ± 5 y) were included. Restrictive diets (low salt n = 33, diabetic n = 19, low cholesterol n = 15, combination n = 27) had been followed since 11.0 ± 5.9 years. Using the cut-off of 12 for MNA-SF(®), 44 patients in the diet group were at risk vs. 22 among controls (P < 0.001). In multivariate analysis, a restrictive diet increased the probability of having an MNA-SF(®) < 12 (OR = 3.6, (95%)CI = 1.8-7.2, P < .001). CONCLUSIONS: Restrictive diets in patients over 75 increase the risk of undernutrition. On an individual level, these diets may need reassessment. Society guidelines should promote specific recommendations for the elderly.


Subject(s)
Diet, Diabetic , Diet, Fat-Restricted , Diet, Sodium-Restricted , Elder Nutritional Physiological Phenomena , Malnutrition/epidemiology , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Male , Multivariate Analysis , Nutrition Assessment , Prospective Studies , Risk Factors
5.
Inflamm Bowel Dis ; 14(11): 1562-8, 2008 Nov.
Article in English | MEDLINE | ID: mdl-18478564

ABSTRACT

BACKGROUND: Patients with Crohn's disease (CD) are prone to osteoporosis. A loss of muscle mass, called sarcopenia, is responsible for an increased risk of disability. Many factors associated with osteopenia also decrease muscle mass. The aim of the present study was to measure the prevalence of sarcopenia in CD patients in remission and uncover its relationship with osteopenia. METHODS: In all, 82 CD patients (43 female/39 male; 36 +/- 14 years; body mass index [BMI] 21.1 +/- 3.4) and 50 healthy volunteers (30F/20M; 39 +/- 13 years; BMI 22.2 +/- 2.5) were studied. Body composition was assessed using dual-energy x-ray absorptiometry. Sarcopenia was defined as an appendicular skeletal muscle index (ASMI) below 5.45 kg/m(2) for women and 7.26 for men. Osteopenia was defined as a T-score for bone mineral density (BMD) (g/cm(2)) below -1.0. RESULTS: In all, 60% of CD patients were found to be sarcopenic and 30% osteopenic, compared to 16% and 4% of controls, respectively (P < 0.01). ASMI was significantly lower in patients than in controls (6.0 +/- 1.1 versus 6.5 +/- 1.2; P < 0.05). Sarcopenic patients had significantly (P < 0.01) lower BMI (20.0 +/- 3.5 versus 22.7 +/- 2.8 kg/m(2)), lean mass (41.5 +/- 9.1 versus 48.1 +/- 9.1 kg), and BMD (1.09 +/- 0.12 versus 1.15 +/- 0.08 g/cm(2)) than nonsarcopenic patients; 91% of sarcopenic patients were also osteopenic. ASMI correlated with BMD (r = 0.46; P < 0.01) and BMI (r = 0.38; P < 0.01). CONCLUSIONS: The prevalence of sarcopenia is high in young CD patients and strongly related to osteopenia. These 2 phenomena may share similar mechanisms. Simultaneous screening for sarcopenia and osteopenia may be useful in CD patients.


Subject(s)
Bone Diseases, Metabolic/epidemiology , Crohn Disease/epidemiology , Muscular Atrophy/epidemiology , Osteoporosis/epidemiology , Adult , Age Distribution , Analysis of Variance , Anthropometry , Body Composition , Body Mass Index , Bone Density , Bone Diseases, Metabolic/diagnosis , Case-Control Studies , Cohort Studies , Comorbidity , Crohn Disease/diagnosis , Female , Follow-Up Studies , Humans , Male , Middle Aged , Muscle Strength , Muscular Atrophy/diagnosis , Osteoporosis/diagnosis , Prevalence , Probability , Reference Values , Regression Analysis , Risk Assessment , Severity of Illness Index , Sex Distribution , Young Adult
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