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1.
J Chemother ; 19 Suppl 2: 17-9, 2007 Oct.
Article in English | MEDLINE | ID: mdl-18073173

ABSTRACT

Chorioamnionitis is an inflammation of the placental membranes induced by microorganisms which reach the endometrial cavity from the vagina and uterine cervix. Premature labor frequently depends on infections. In patients with premature rupture of membranes (PROM) antibiotic treatment can prevent intra-amniotic inflammation if it is absent at admission. In spite of antibiotic treatment started immediately after the PROM in 218 patients, the chorioamnionitis did not prevent delivery in 41 patients within 48 hours of PROM. In the presence of a previous chorioamnionitis, antibiotic treatment cannot prevent premature labor, whereas it can prevent infection and lead to a longer duration of pregnancy if PROM does not depend on previous infection.


Subject(s)
Chorioamnionitis , Pregnancy Complications, Infectious , Anti-Bacterial Agents/therapeutic use , Brain Diseases/etiology , Brain Diseases/prevention & control , Chorioamnionitis/drug therapy , Cytokines/metabolism , Female , Humans , Infant, Newborn , Lung Diseases/etiology , Lung Diseases/prevention & control , Obstetric Labor, Premature/etiology , Obstetric Labor, Premature/prevention & control , Pregnancy , Pregnancy Complications, Infectious/drug therapy
2.
Neurology ; 62(2): 301-3, 2004 Jan 27.
Article in English | MEDLINE | ID: mdl-14745075

ABSTRACT

The authors investigated whether testosterone levels and testosterone availability differ between older lean subjects with and without Alzheimer's disease (AD). Sex hormone binding globulin (SHBG) and estradiol levels were higher, whereas the free androgenization index (FAI) was lower, in lean subjects with AD than in lean subjects without AD. Factors involved in the increase of SHBG secretion could have an important role in the lower testosterone availability of subjects with AD.


Subject(s)
Alzheimer Disease/blood , Testosterone/blood , Aged , Body Mass Index , Dehydroepiandrosterone Sulfate/blood , Estradiol/blood , Female , Humans , Hydrocortisone/blood , Male , Sex Hormone-Binding Globulin/analysis , Testosterone/deficiency , Thinness/blood
3.
Minerva Chir ; 49(10): 929-33, 1994 Oct.
Article in Italian | MEDLINE | ID: mdl-7808666

ABSTRACT

An experience of surgical non-thoracic emergencies in patients admitted for chronic lung disease is herein presented. Fifty-four patients out of 10457 admitted in the four Departments of Pneumology of the Binaghi Hospital (Cagliari) between 1-1-1985 and 31-3-1993, were referred to our Department of General Surgery due to non-thoracic surgical emergencies. There was a considerable delay in the referral (only 25% of patients within 12 hours from the onset of symptoms): indeed predominant respiratory symptoms, hypoxia and hypercapnia made these patients no responsive to symptoms of surgical emergency. Surgical emergencies in causal correlation with respiratory disease (intestinal occlusion due to abdominal metastases of lung carcinoma, complicated peptic ulcer) had the worst prognosis (mortality: 52.9%). Those in chance connection, such as acute limb ischemia and preexisting abdominal disease, had a less adverse outcome. Mortality, however, was 37.5%: this datum outlines the role of chronic lung disease in defining operative risk. The authors call attention to three groups of observed patients: 1) three patients were operated on for intestinal occlusion due to unrecognized abdominal neoplasia, that showed itself in the course of hospitalization in the Department of Pneumology for lung metastases; 2) in 3 cases symptoms and signs of acute abdomen were observed without abdominal disease. The cause of acute pseudoabdomen was diaphragmatic pleural or basal pulmonary inflammation; 3) the eight patients with pulmonary embolism were all admitted in the Department of Pneumology with a wrong diagnosis of bronchopneumonia.


Subject(s)
Emergencies , Lung Diseases/complications , Surgical Procedures, Operative , Adult , Aged , Aged, 80 and over , Chronic Disease , Female , Hospitalization , Humans , Lung Diseases/mortality , Male , Middle Aged , Retrospective Studies , Risk Factors , Surgical Procedures, Operative/mortality
4.
J Craniofac Genet Dev Biol ; 13(2): 109-16, 1993.
Article in English | MEDLINE | ID: mdl-8325966

ABSTRACT

A cross-sectional study of tooth maturation was carried out in a group of 382 healthy children (178 boys and 204 girls) from Sardinia. A single orthopantomogram was examined for each patient and the development of permanent mandibular canines, premolars, and molars was evaluated according to Moorrees' method [Moorrees CFA, Fanning EA, Hunt EE: J Dent Res 42:1490-1502, 1963] Dental maturity scores and chronological ages were processed by linear regression analysis. Significant differences were observed in the timing of tooth development between boys and girls. A visual comparison with North American children revealed appreciable differences between the two populations, accounting for a delayed dental maturation in Sardinian children.


Subject(s)
Tooth/growth & development , Cross-Sectional Studies , Female , Humans , Infant , Italy , Male , North America , Regression Analysis
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