ABSTRACT
UNLABELLED: Kingella kingae is the second most frequent germ involved in arthritis affecting young children. This germ isolation on ordinary environment is difficult, which may explain why it is seldom known. It is now widely accepted that a direct inoculate of articular and osseous samples on liquid substrate improves the culture sensitivity. Other septic localizations have been described such as endocarditis or, less commonly, meningitis. CASE REPORT: We report the observation of a five-year-old child, treated for meningitis, with CSF culture showing evidence of scarce colonies of Kingella kingae. CONCLUSION: By analogy with arthritis, Kingella kingae may regularly be undetected, not being isolated, in some cases of non-documented meningitis with a cerebrospinal fluid (CSF) cytology recalling a bacterial origin. It would be of interest to verify if the seeding of CSF in liquid substrate would increase the sensitiveness of the cultures.
Subject(s)
Kingella kingae , Meningitis, Bacterial/etiology , Neisseriaceae Infections , Ceftriaxone/administration & dosage , Ceftriaxone/therapeutic use , Cephalosporins/administration & dosage , Cephalosporins/therapeutic use , Cerebrospinal Fluid/microbiology , Child, Preschool , Follow-Up Studies , Gentamicins/administration & dosage , Gentamicins/therapeutic use , Humans , Kingella kingae/isolation & purification , Male , Meningitis, Bacterial/cerebrospinal fluid , Meningitis, Bacterial/diagnosis , Meningitis, Bacterial/drug therapy , Netilmicin/administration & dosage , Netilmicin/therapeutic use , Time FactorsABSTRACT
UNLABELLED: Cat-scratch disease is a well-known cause of regional adenopathy in immunocompetent children. Rarely, patients may present with symptoms simulating a neoplastic disease. The case of a 12-year-old boy with fever, swelling of the chest wall and hepatosplenic nodules is reported. Histological analysis of biopsy specimen obtained from the chest wall lesion and the liver revealed granulomatous reaction without malignant cells. Serological investigations were positive for Bartonella species. The symptoms and the lesions disappeared after oral antibiotic therapy (ciprofloxacin) was started. The patient remained symptom-free 12 months later. CONCLUSION: The present case emphasizes the wide spectrum of clinical manifestations associated with cat-scratch disease which should be investigated as differential diagnosis of manifestations suggesting a neoplastic disease in children.