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Article in Russian | MEDLINE | ID: mdl-331769

ABSTRACT

Dilatation of the endoplasmic reticulum cavities, an increase in the number of ribosomes near bacteria, deformation of mitochondria and coarsening of cristae were revealed in phagocytosis of Past. pestis, strain EV, by reticular cells in the tissue culture of the spleen of intact guinea pigs. Lipophanerous "reticular" inclusions were found in the differentiated reticular cells of the infected cultures. In the reticular cell cytoplasma besides the intact bacteria there were revealed Past. pestis at the initial stages of involution.


Subject(s)
Spleen/ultrastructure , Yersinia pestis/ultrastructure , Animals , Cells, Cultured , Endoplasmic Reticulum/ultrastructure , Guinea Pigs , History of Medicine , In Vitro Techniques , Mitochondria/ultrastructure , Phagocytosis , Plague/microbiology , Plague/pathology , Ribosomes/ultrastructure , Yersinia pestis/immunology
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