ABSTRACT
Objective: To establish and evaluate a nomogram model for predicting the risk of postpartum hemorrhage in second cesarean section. Methods: A total of 440 parturients who underwent the second cesarean section surgery and were registered in our hospital from August 2019 to July 2021 were selected as the study subjects. They were randomly divided into 220 modeling group and 220 validation group based on simple randomization. The two groups were divided into postpartum hemorrhage group and postpartum non bleeding group according to whether postpartum hemorrhage occurred. Results: In the modeling group, the incidence of postpartum hemorrhage in the second cesarean section was 15.00%; the Logistic regression model showed that placenta previa, operation time, prenatal anemia, placenta accreta, uterine inertia were the independent risk factors of postpartum hemorrhage in the second cesarean section (P < 0.05). ROC results showed that AUC of predicting the risk of postpartum hemorrhage in the second cesarean section was 0.824. The slope of calibration curve is close to 1, Hosmer-Lemeshow goodness of fit test showed x2= 7.585, P = 0.250. The external verification results show that the AUC is 0.840, and the predicted probability of the calibration curve is close to the actual probability. Conclusion: Based on the five risk factors of postpartum hemorrhage in the second cesarean section, including placenta previa, operation time, prenatal anemia, placenta accreta and uterine inertia, the nomogram model for predicting the risk of postpartum hemorrhage in the second cesarean section has good accuracy and differentiation.
ABSTRACT
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a newly emerging coronavirus. This virus poses a great threat to human society and has been marked as the third introduction of a highly pathogenic coronavirus into the human population. This is following severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) in the 21st-century. While China has achieved initial success in controlling the spread of COVID-19 and treating those infected with SARS-CoV-2, up to 14% of COVID-19 convalescents can still be detected with virus nucleic acid. Thus, there is an urgent need for more information to understand this new virus. Here we report the detailed clinical characteristics of three cases of COVID-19 convalescents that had repeated positive quantitative reverse transcription-polymerase chain reaction (qRT-PCR) test results for over three months. This may arouse concerns regarding the present quarantine protocol after convalescence and provide a reference for governments to consider when to reopen the community.
